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41.
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Lesions of the lateral trochlear ridge (LTR) of the distal femur were investigated in four pony or pony cross horses. The animals were all geldings and were six to 15 months of age. Lesions were bilateral in three ponies and unilateral in one. Femoropatellar joint effusion and lameness were present in two ponies; clinical signs were absent in the others. The proximal LTR was affected in all four animals. The radiographic appearance of the lesions was a subchondral defect containing mineralised bodies. Arthroscopic and postmortem examination findings included an osteochondral flap, a fissured or irregular articular surface and a smooth surface overlying focally thickened cartilage that extended into subchondral bone. Thickened articular cartilage was a histological feature of all the lesions. Among the other histological features, the most common were chondronecrosis, chondrocyte clusters, phenotypically abnormal chondrocytes, horizontal fissures at the osteochondral junction and retained blood vessels. The signalment of the four ponies, their clinical signs and the pathological features of their lesions were consistent with osteochondrosis of the LTR in horses. The use of multiple criteria was considered to be important in making a specific diagnosis. 相似文献
43.
de Stefani A de Risio L Platt SR Matiasek L Lujan-Feliu-Pascual A Garosi LS 《Veterinary surgery : VS》2011,40(2):183-191
Objective: To report frequency and type of complications, and outcome in dogs with severe neurologic signs secondary to internal, suspected obstructive hydrocephalus treated by ventriculoperitoneal (VP) shunting. Study Design: Case series. Animals: Dogs (n=14). Methods: Medical records (2001–2006) was reviewed for dogs that had VP shunting. Inclusion criteria were complete medical record, progressive forebrain signs unresponsive to medical treatment, normal metabolic profile, negative antibody titers and/or cerebrospinal PCR for Toxoplasma gondii, Neospora caninum, and canine distemper virus, magnetic resonance images of the brain, confirmed diagnosis of VP shunting, and follow‐up information. Results: Hydrocephalus was idiopathic in 5 dogs and acquired (interventricular tumors, intraventricular hemorrhage, inflammatory disease) in 9 dogs. Four dogs developed complications 1 week to 18 months postoperatively, including ventricular catheter migration, infection, shunt under‐drainage, kinking of the peritoneal catheter, valve fracture, and abdominal skin necrosis. Three of these dogs had 1 or more successful revision surgeries and 1 dog was successfully treated with antibiotics. All, but 1 dog, were discharged within 1 week of surgery, and had substantial neurologic improvement. Median survival time for all dogs was 320 days (1–2340 days), for dogs with idiopathic hydrocephalus, 274 (60–420) days and for dogs with secondary hydrocephalus, 365 (1–2340) days. Conclusions: VP shunting was successful in relieving neurologic signs in most dogs and postoperative complications occurred in 29%, but were resolved medically or surgically. 相似文献
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Steven R. James Lori Wing Ronald Knight Barbara Harrity Devid H. Lambert Bud Platt Al Reeves Bill Bohl Lind Sanford Alexander D. Pavlista Ed Plissey Richard Sawyer Joe Guenthner Willem Schrage Edward B. Radcilffe Nora Olsen Jeff Miller Rikki Sterrett Gale W. Harding Marcin Topoleweki 《American Journal of Potato Research》2000,77(6):369-390
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The vertical flux of nitrate across the thermocline in the upper ocean imposes a rigorous constraint on the rate of export of organic carbon from the surface layer of the sea. This export is the primary means by which the oceans can serve as a sink for atmospheric carbon dioxide. For the oligotrophic open ocean regions, which make up more than 75% of the world's ocean, the rate of export is currently uncertain by an order of magnitude. For most of the year, the vertical flux of nitrate is that due to vertical turbulent transport of deep water rich in nitrate into the relatively impoverished surface layer. Direct measurements of rates of turbulent kinetic energy dissipation, coupled with highly resolved vertical profiles of nitrate and density in the oligotrophic eastern Atlantic showed that the rate of transport, averaged over 2 weeks, was 0.14 (0.002 to 0.89, 95% confidence interval) millimole of nitrate per square meter per day and was statistically no different from the integrated rate of nitrate uptake as measured by incorporation of (15)N-labeled nitrate. The stoichiometrically equivalent loss of carbon from the upper ocean, which is the relevant quantity for the carbon dioxide and climate question, is then fixed at 0.90 (0.01 to 5.70) millimole of carbon per square meter per day. These rates are much lower than recent estimates based on in situ changes in oxygen over annual scales; they are consistent with a biologically unproductive oligotrophic ocean. 相似文献
48.
Carley J. Abramson Laurent Garosi Simon R. Platt Ruth Dennis J. Fraser McConnell 《Veterinary radiology & ultrasound》2005,46(3):225-229
Ischemia and infarction of the spinal cord is a known cause of acute spinal injury in dogs. Currently, the diagnosis of spinal cord infarction in small animals is based on history, clinical signs, and the exclusion of other differentials with radiography and myelography. It is a diagnosis only confirmed through necropsy examination of the spinal cord. The aim of this paper is to describe the Magnetic resonance imaging (MRI) findings of the spinal cord of dogs with suspected spinal cord infarcts to utilize this technology for antemortem support of this diagnosis. This retrospective study evaluated the spinal MR examinations of 11 dogs with acute onset of asymmetric nonpainful myelopathies. All patients except one (imaged at 2 months) were imaged within 1 week of clinical signs and managed conservatively with minimal medical and no surgical intervention. They were followed clinically for a minimum of 4 months after discharge. MR findings in all dogs were characterized by focal, intramedullary, hyperintense lesions on T2-weighted images with variable contrast enhancement similar to what is reported in humans. Though it could not be used to diagnose spinal cord infarction definitively, MRI was useful in excluding extramedullary spinal lesions and supporting intramedullary infarction as a cause of the acute neurologic signs. Together with the history and clinical examination findings, MRI is supportive of a diagnosis of spinal cord infarction. 相似文献
49.
A Placebo‐Controlled,Prospective, Randomized Clinical Trial of Polyethylene Glycol and Methylprednisolone Sodium Succinate in Dogs with Intervertebral Disk Herniation 下载免费PDF全文
50.
Julie Kornder Simon R. Platt Joe Eagleson Marc Kent Shannon P. Holmes 《Veterinary radiology & ultrasound》2016,57(4):E42-E45
A 9‐year‐old spayed female Scottish terrier presented with an 8‐day history of progressive paraparesis. Neurological examination suggested a painful T3‐L3 myelopathy. Multifocal uniform contrast‐enhancing masses involving the vertebral bodies, pedicles, laminae, and spinous processes of two vertebrae and compressing the spinal cord were present on MRI. Fluoroscopic‐guided fine needle aspiration of one of the vertebral lesions revealed a predominantly lymphoblastic population of cells compatible with a diagnosis of lymphoma. To the authors’ knowledge, this represents the first published case of canine lymphoma with vertebral involvement, characterized with MRI. 相似文献