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Objective To determine the severity and distribution of structural changes in the brains of adult sheep stunned by penetrating captive bolt.
Procedure The unconstrained heads of ten, anaesthetised, unhorned, 2-year-old Merino sheep were impacted at the summit of the head with a penetrating captive bolt pistol. Six sheep were ventilated and four received no respiratory support. Two hours after impact, brains from the six ventilated sheep were perfusion-fixed with 4% paraformaldehyde. Sixteen whole, serial coronal sections from each brain were stained with haematoxylin and eosin and immunohistochemi-cally for amyloid precursor protein, a sensitive marker of axonal and neuronal reaction in the brain after trauma. Pathological changes in these brains were then quantified by morphometric analysis.
Results Structural change in all impacted brains was a mixture of focal injury around the wound track and more widely distributed damage in the cerebral hemispheres, cerebellum and brainstem, but varied considerably in severity between individual sheep. All nonventilated sheep died rapidly following respiratory arrest.
Conclusions After penetrating captive bolt stunning, damage to the central reticular formation, axonal connections, and the cortical mantle is the likely reason for failure of respiratory control and traumatic loss of consciousness. 相似文献
Procedure The unconstrained heads of ten, anaesthetised, unhorned, 2-year-old Merino sheep were impacted at the summit of the head with a penetrating captive bolt pistol. Six sheep were ventilated and four received no respiratory support. Two hours after impact, brains from the six ventilated sheep were perfusion-fixed with 4% paraformaldehyde. Sixteen whole, serial coronal sections from each brain were stained with haematoxylin and eosin and immunohistochemi-cally for amyloid precursor protein, a sensitive marker of axonal and neuronal reaction in the brain after trauma. Pathological changes in these brains were then quantified by morphometric analysis.
Results Structural change in all impacted brains was a mixture of focal injury around the wound track and more widely distributed damage in the cerebral hemispheres, cerebellum and brainstem, but varied considerably in severity between individual sheep. All nonventilated sheep died rapidly following respiratory arrest.
Conclusions After penetrating captive bolt stunning, damage to the central reticular formation, axonal connections, and the cortical mantle is the likely reason for failure of respiratory control and traumatic loss of consciousness. 相似文献
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BA Hampson G Ramsey AMH Macintosh PC Mills MA De Laat CC Pollitt 《Australian veterinary journal》2010,88(4):124-131
Objective The present study investigated the foot health of the Kaimanawa feral horse population and tested the hypotheses that horses would have a large range of foot morphology and that the incidence of foot abnormality would be significantly high. Procedures Abnormality was defined as a variation from what the two veterinarian assessors considered as optimal morphology and which was considered to impact negatively on the structure and/or function of the foot. Fifteen morphometric variables were measured on four calibrated photographic views of all four feet of 20 adult Kaimanawa feral horses. Four morphometric variables were measured from the lateromedial radiographs of the left forefoot of each horse. In addition, the study identified the incidence of gross abnormality observed on the photographs and radiographs of all 80 feet. Results There was a large variation between horses in the morphometric dimensions, indicating an inconsistent foot type. Mean hoof variables were outside the normal range recommended by veterinarians and hoof care providers; 35% of all feet had a long toe conformation and 15% had a mediolateral imbalance. Abnormalities included lateral (85% of horses) and dorsal (90% of horses) wall flares, presence of laminar rings (80% of horses) and bull-nose tip of the distal phalanx (75% of horses). Both hypotheses were therefore accepted. Conclusions The Kaimanawa feral horse population demonstrated a broad range of foot abnormalities and we propose that one reason for the questionable foot health and conformation is lack of abrasive wearing by the environment. In comparison with other feral horse populations in Australia and America there may be less pressure on the natural selection of the foot of the Kaimanawa horses by the forgiving environment of the Kaimanawa Ranges. Contrary to popular belief, the feral horse foot type should not be used as an ideal model for the domestic horse foot. 相似文献
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ML Lepherd PJ Canfield GB Hunt PC Thomson KL Bosward 《Australian veterinary journal》2011,89(7):238-238
65.
JN MILLS 《Australian veterinary journal》1997,75(7):497-499
Objective To describe a teaching experiment in which fifth year veterinary students were given the opportunity, using dramatic scenarios, to consider ways of dealing with emotive issues relevant to veterinary practice, that demand good communication skills.
Design Workshops were devised using dramatised scenarios of several critical incidents in practice, including euthanasia. A clinical psychologist and several veterinary practitioners participated in discussions. Both live performances and video scenarios were presented to fifth year veterinary students and were followed by group discussions. Each workshop was evaluated and modifications were made where necessary.
Results The teaching format involving drama was well received. The combination of drama and discussion was more effective than a formal talk and discussion, provoking animated participation and maintaining audience attention. The majority of students considered that comments and advice from attending veterinarians were the most useful parts of the workshops in preparing them for veterinary practice. The large audience (up to 45 attendees) was considered to be desirable for enhancing discussion. Requests for more similar sessions were made by students.
Conclusion Drama was found to be a satisfactory modality in teaching communication skills in preparing veterinary students for practice. 相似文献
Design Workshops were devised using dramatised scenarios of several critical incidents in practice, including euthanasia. A clinical psychologist and several veterinary practitioners participated in discussions. Both live performances and video scenarios were presented to fifth year veterinary students and were followed by group discussions. Each workshop was evaluated and modifications were made where necessary.
Results The teaching format involving drama was well received. The combination of drama and discussion was more effective than a formal talk and discussion, provoking animated participation and maintaining audience attention. The majority of students considered that comments and advice from attending veterinarians were the most useful parts of the workshops in preparing them for veterinary practice. The large audience (up to 45 attendees) was considered to be desirable for enhancing discussion. Requests for more similar sessions were made by students.
Conclusion Drama was found to be a satisfactory modality in teaching communication skills in preparing veterinary students for practice. 相似文献
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SUMMARY The concentrations of phenylbutazone (PBZ), oxyphenbutazone (OPBZ) and gammahydroxyphenylbutazone (OHPBZ) in plasma and urine from 50 Greyhounds 24 and 48 h after the intravenous administration of a single dose of PBZ (30 mg/kg) were measured. The 24 h plasma concentrations of OPBZ and OHPBZ, the 48 h plasma concentration of OHPBZ and the 24 h urinary concentration of PBZ were normally distributed, while log transformations were required before the 24 h plasma concentration of PBZ and the 24 and 48 h urinary concentrations of OPBZ and OHPBZ became normally distributed. The 95%, 99%, 99.9% and 99.99% upper predicted confidence intervals for both 24 h and 48 h plasma and urinary concentrations demonstrated wide potential variation in the concentration of the analytes should PBZ be administered to Greyhounds. The 24 h plasma and urinary concentrations of PBZ were weakly correlated, but no similar relationship existed for OPBZ or OHPBZ. The urinary concentrations of each analyte were not affected by the trainer or sex of the Greyhound or the urinary pH. We conclude that it would be impossible to predict the timing of the PBZ administration or the plasma concentration of PBZ from the measurement of the concentration of PBZ in a single sample of urine. 相似文献
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