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121.
Colm J. Reid Samantha Donnelly David J. Marlin Jane A. Irwin 《Research in veterinary science》2009,87(1):20-25
Recurrent airway obstruction (RAO) is a chronic inflammatory condition in equine lung, which may share a common immunological basis with human asthma, in which dysregulated Th2 responses occur. Mammals express chitinases and chitinase-like proteins, two of which are active enzymes, chitotriosidase and acidic mammalian chitinase (AMCase). Both enzymes are upregulated in a range of inflammatory conditions, including asthma. We investigated the activity of chitinase in bronchoalveolar lavage fluid from horses with and without RAO in response to organic dust challenges. No significant differences were found in activity, although in one study RAO animals had elevated chitinase activity that fell short of statistical significance. The pH optimum and pH lability of the activity was consistent with the presence of chitotriosidase. RT-PCR amplification of the mRNA encoding chitotriosidase and AMCase in normal equine lung showed that chitotriosidase, but not AMCase, is expressed in trachea, bronchi, and peripheral lung tissue. The gene for chitotriosidase was identified from the Equus caballus (horse) genome 1.1 database and its similarity to the same genes from other species was determined. The results of this study indicate that the involvement of chitotriosidase in RAO is uncertain. 相似文献
122.
Musculoskeletal injuries (MSI) in racehorses have been identified as the most common cause of lost training days and weeks spent resting at pasture. Several training-, track- and horse-related risk factors have been identified. However, there is no clear understanding of the inter-relationship between these factors. The aim of this longitudinal cohort study was to investigate risk factors for MSI in 2-year-old Thoroughbred racehorses. Australian Thoroughbred trainers were convenience sampled and enrolled in a 27-month longitudinal cohort study. The study population consisted of all 2-year-old Thoroughbred racehorses trained by a participating trainer. Horses were followed from the time of enrollment until the completion of the study or until they were lost to follow-up. Trainers were visited at approximately 14-day intervals to collect training and injury data. Training days were categorised as fast days if the maximum speed during training exceeded 800 m/min. For each horse, the first training period that included one or more fast days was analysed. A multiple logistic regression model was used to determine those horse- and training-related variables that were associated with MSI. Data from 274 horses trained by 14 trainers at five racetracks were analysed. Forty percent of the horses sustained a MSI during their first fast preparation. The average distance trained at speeds >or=800 m/min and the percentages of fast days from the first fast day until the end of the preparation were the only variables associated with MSI. After accounting for these variables there were still significant differences between trainers. This suggests that there are other training-related variables such as the rate of increase in distance trained at speeds >or=800 m/min that may be risk factors for MSI. In addition, other factors such as the level of veterinary involvement and the training centre/racetrack may be risk factors for MSI. More analysis using multi-level modelling is required to determine the relationship between trainer- and track-related risk factors. 相似文献
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124.
Taddese Fasil Reid Malcolm Heim-Ballew Heidi Jarvis Matt G. Closs Gerard P. 《Fisheries Science》2021,87(3):271-281
Fisheries Science - Understanding the role different habitats play in the life histories of fishes is important for the development of holistic aquatic ecosystem management plans. We used otolith... 相似文献
125.
Organic spring wheat (Triticum aestivum L.) producers in the northern Great Plains use cultivars which have been bred for conventional management systems or heritage
cultivars released before the widespread use of synthetic fertilizers and pesticides. To investigate the feasibility of organic
wheat breeding and to determine common genetic parameters for each system, we used a random population of 79 F6-derived recombinant inbred sister lines from a cross between the Canadian hard red spring wheat cultivar AC Barrie and the
CIMMYT derived cultivar Attila. The population, including the parents, was grown on conventionally and organically managed
land for 3 years. Heritability estimates differed between systems for 6 of the 14 traits measured, including spikes m−2, plant height, test weight, 1,000 kernel weight, grain protein, and days to anthesis. Direct selection in each management
system (10% selection intensity) resulted in 50% or fewer lines selected in common for nine traits, including grain yield,
grain protein, spikes m−2, and grain fill duration. The results of this study suggest that indirect selection (in conventionally managed trials) of
spring wheat destined for organically managed production would not result in the advance of the best possible lines in a breeding
program. This implies that breeding spring wheat specific to organic agriculture should be conducted on organically managed
land. 相似文献
126.
Gregory H. Reid 《Agriculture and Human Values》2009,26(4):391-397
In response to a drying climate, an integrated property planning tool was developed over three years to help landowners make
better use of available rainfall. A sequence was identified which indicated how parts of each property are affected by soil
moisture limitations. The sequence was combined with soil properties to indicate targeted strategies for each location aimed
to improve soil moisture availability, biomass utilisation, and long-term viability of the farm or ranching enterprise. As
a result of training of land owners and operators in use of this tool, 97% of participants indicated that they have begun
or intend to make changes in land management; 78% are intending to make three or more substantial changes; and 91% felt better
prepared for the impacts of climate change. The key to the success of this technique is that it identifies critical sustainable
production drivers in a simple plan format and offers tailored management options which can address more variable climate
conditions. The integrated planning tool has application as a driver of climate change adaptation in agricultural regions
where farm units contain substantial landscape variation and seasonal rainfall is frequently limiting to production. 相似文献
127.
Use of Yunnan Baiyao and epsilon aminocaproic acid in dogs with right atrial masses and pericardial effusion
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129.
Objective To investigate the effect of a topical anaesthetic formulation on pain alleviation, wound healing and systemic levels of local anaesthetic actives in lambs undergoing castration and tail docking. Design Three placebo-controlled and/or randomised experiments were conducted using three groups of Merino lambs (n = 62, 68 and 19) undergoing routine castration and tail docking. Procedure Surgical castration, with either surgical or hot-iron tail docking, was performed with and without the application of topical anaesthetic (Tri-Solfen®) or placebo. The effects of this procedure were compared with those of rubber ring castration and tail docking, and of the handled but unmarked controls. Wound pain was assessed using calibrated Von-Frey monofilaments over a 4-h period, pain-related behaviour was assessed over 5 h, wound healing was assessed at 14 and 28 days, and the plasma levels of lignocaine and bupivacaine were determined. Results Rapid and up to 4 h primary hyperalgesia developed following surgical castration and tail docking in the untreated and placebo-treated lambs. It was absent in the castration wounds, and significantly reduced in the tail-docking wounds, of the treated lambs. Hot-iron docking was associated with mild and transient secondary hyperalgesia, which was abolished by the topical anaesthesia. There was a significant reduction in pain-related behaviours in treated lambs, which were not significantly different in their behaviour to the sham-operation handled controls. Plasma lignocaine and bupivacaine levels were below the toxic thresholds in all tested lambs. Conclusion Topical anaesthesia alleviates wound pain and significantly reduces pain-related behaviours in lambs undergoing surgical castration plus surgical or hot-iron tail docking, without a negative effect on wound healing or a risk of systemic toxicity. 相似文献
130.
Todd R. Hamilton VMD Christopher W. Thacher DVM DACVS Kara M. Forsee DVM Reid K. Nakamura DVM DACVECC 《Journal of Veterinary Emergency and Critical Care》2010,20(6):595-600
Objective – To describe the successful management of acute mesenteric ischemia (AMI) in a dog. Case Summary – An 11‐year‐old, 21.4 kg, male castrated Rough‐Coated Collie was referred for evaluation of an acute abdomen following sustaining injuries in a vehicular accident. On presentation to the hospital, clinicopathologic assessments were within normal limits and distended intestinal loops were evident on abdominal palpation. Plain and contrast radiography demonstrated diffusely distended gas‐filled intestinal loops with a delayed barium transit time. Emergency surgical exploration was performed. The cecum and the proximal two‐thirds of the colon were dark purple to black in color and there were no palpable pulses in the mesenteric arteries associated with the cecum and colon. The cecum and proximal two‐thirds of the colon were resected and an ileocolic anastomosis was performed. The dog recovered well from surgery and was discharged 2 days later. Histopathologic examination was consistent with AMI. New or Unique Information Provided – AMI is uncommonly reported in human medicine and is a rare complication from even minor blunt abdominal trauma. This is the first reported case of trauma‐associated AMI in a dog. 相似文献