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271.
Smith PM Jeffery ND 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2005,19(6):788-793
Spinal shock is the loss of muscle tone and segmental spinal reflexes that develops caudal to a severe spinal cord injury. Although little recognized in the veterinary literature, spinal shock occurs in animals and is important in both accurate lesion localization and case management. In this review, we consider why spinal shock occurs and discuss the subsequent physiologic alterations, including the development of reflex hyperactivity. We also discuss differences in the expression of spinal shock between species and suggest why recovery of reflexes is relatively rapid in animals compared with humans. Finally, the implications for clinicians dealing with animals in the period immediately after severe spinal injury are considered. 相似文献
272.
Jeffery P. Simmons DVM MS James S. Wohl DVM DACVECC DACVIM Dean D. Schwartz PhD Heather G. Edwards James C. Wright DVM PhD 《Journal of Veterinary Emergency and Critical Care》2006,16(2):96-103
Objective: To determine the effect of fenoldopam infusion on urine output, sodium excretion, creatinine clearance, and indirect blood pressure in healthy cats. Design: Prospective study. Setting: Veterinary medical teaching hospital. Animals: Eight purpose‐bred cats, 2–4 years old. Interventions: None. Measurements: Urine output was measured hourly for 12 hours before and after fenoldopam administration. Sodium excretion, modified creatinine clearance, and fractional sodium excretion were measured before and following fenoldopam administration. Urine specific gravity, central venous pressure, and systolic blood pressure were measured every 4 hours during the experiment. Main results: Compared with pre‐infusion values, urine output, sodium excretion, and fractional excretion of sodium increased significantly 6 hours after initiation of fenoldopam infusion. This increase was sustained throughout the observation period. The modified creatinine clearance decreased significantly following 2 hours of fenoldopam infusion, but increased significantly by 6 hours after infusion, the time of peak urine output. Changes in urine specific gravity mirrored changes in fractional sodium excretion, whereas the central venous pressure mirrored changes in modified creatinine clearance. The diuretic effect in cats was prevented when a dopamine receptor blocking agent was administered before fenoldopam infusion. Conclusion: Fenoldopam at a dose of 0.5 μg/kg/min induces diuresis in cats in a delayed manner. This increase appears to be due, in part, to dopamine receptor‐induced natriuresis. Changes in glomerular filtration rate may also occur. 相似文献
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Craig B. Struble Vernon J. Feil Jerome C. Pekas Jeffery W. Gerst 《Pesticide biochemistry and physiology》1983,19(1):85-94
The biliary secretion of 14C was observed in conscious, bile-fistulated rats given single oral doses of [14C]carbaryl (1.5, 30, and 300 mg/kg). Over 94% of the 14C was absorbed after 12 hr. From 15 to 46% of the 14C was secreted in bile, 10–40% in urine, and less than 1% in feces 12 hr after dosing. Three metabolites were isolated from bile and identified by mass and/or NMR spectrometric methods. These metabolites were: 5,6-dihydro-5,6-dihydroxycarbaryl glucuronide (12–18% of the biliary 14C), a conjugate(s) of carbaryl (12% of the biliary 14C), and conjugated isomers of hydroxy-carbaryl (2% of the biliary 14C). The majority of the biliary 14C remains to be identified. 相似文献
275.
N. D. Jeffery 《The Journal of small animal practice》1989,30(12):674-677
A quick surgical approach for internal reduction and fixation of femoral head and neck fractures is described. The results and reasons for preferring this technique to femoral head and neck excision are discussed. 相似文献
276.
Paul B. Thompson Keith M. Moore William M. Rivera Gary P. Green Joel Schor Richard W. Ryan Jeffery W. Bentley Bernard den Ouden William P. Browne 《Agriculture and Human Values》1989,6(4):62-80
Paul Thompson is Associate Professor of Philosophy and Agricultural Economics at Texas A&M University. He is currently conducting research under a grant from the National Science Foundation, Ethics and Value Studies program on the role of ethics and values in the planning of agricultural research activities, and completing a textbook entitledEthics, Public Policy and Agiculture with Eileen Olsen VanRavenswaay and Robert Matthews slated for publication by Macmillan in 1990. 相似文献
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