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11.
Suzuki J Miwa N Kumazaki K Abe M Kamanaka Y Matsubayashi N Gotoh S Matsubayashi K 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2001,63(4):361-366
To clarify the influence of rearing conditions on the growth of various body parts of Japanese macaques (Macaca fuscata), two groups reared under different conditions, i.e., a group born and reared in open enclosures (Enclosure group) and another consisting of macaques born and reared in cages (Caged group), were somatometrically analyzed. Somatometric data on 36 measures of various body parts were collected from 77 males and 92 females. Growth in many body parts was smaller in the Caged group than in the Enclosure group. Body parts that exhibited large incremental increases were more sensitive to differences in rearing space at the infantile growth stage in both sexes. Recovery from delayed growth at the pubertal growth stage was found in many body parts. However, the size of some locomotor elements such as the wrist and hand, and ankle and foot strongly reflected limitations of space and changes due to this were irreversible. Females were more sensitive than males to such differences in rearing conditions. We conclude that open enclosures with ample rearing space are necessary for the innate growth of Japanese macaques to occur. 相似文献
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Endometrial adenocarcinoma in the uterine corpus is a malignant cancer that occurs in menopausal women and aged rodents. Because of the similarities in pathogenesis and morphology of endometrial adenocarcinoma in rodents and humans, prediction of the modes of action (MOA) in uterine carcinogenesis is important for extrapolation of rodent data to humans. Three MOAs have been accepted as major pathways for uterine carcinogenesis in rodents: 1) estrogenic activity, 2) increased serum 17beta-estradiiol (E2) to progesterone (P4) ratio and 3) modulation of estrogen metabolism to produce 4-hydroxyestradiol via P450 induction. Inhibition of estrogen excretion and increased aromatase in situ in the tumor are also a potential pathway. Here, chemicals showing uterine carcinogenicity were chosen from approximately 300 pesticides evaluated in Japan within the past decade, and their mechanisms were predicted using parameters from mechanistic and toxicity studies. Seven pesticides increased uterine tumor formation in rats, and the pathways of 4 pesticides could be predicted based on various mechanistic studies. The MOAs of cyenopyrafen and benthiavalicarb-isopropyl were predicted to be modulation of estrogen metabolism, while those of pyriminobac-methyl and spirodiclofen were predicted to be increased E2 to P4 ratio. The driven pathways of metazosulfuron and isopyrazam could not be predicted using several mechanistic studies. No mechanistic studies have been reported for sedaxane, which has a chemical structure and toxicological profile similar to isopyrazam. Our results indicated that appropriate mechanistic studies are useful for mechanism prediction in risk assessment. From this analysis, a flowchart showing a decision tree for predictive MOAs in uterine carcinogenesis was proposed. 相似文献
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15.
1. The content of chondroitin sulphate (CS), known as a nutraceutical, was estimated in broiler chicken carcasses by analysing sulphated glycosaminoglycan uronic acid in posterior sternum (keel) cartilage and bones from 4 parts (wing, leg, front and hind) of carcasses.
2. The results of the present study suggested that approximately 0.63 g CS uronic acid (or 1.9 g as CS) can be extracted from a 1.66 kg whole broiler chicken carcass. The amount of extractable CS from keel cartilage, which has been reported as a valuable source of CS in broiler chicken carcasses, was surprisingly low (<10% of total CS). 相似文献
16.
To understand the relationships between shell growth and some environmental factors, we examined the relationships between water temperature or chlorophyll abundance and the shell growth of the Japanese pearl oyster, Pinctada fucata martensii, suspended at three different depths at two sites. Growth in height, length and thickness of the shells were limited by water temperature during winter (< 20 °C), whereas growth in thickness correlated with food abundance, measured as chlorophyll, during early summer (> 20 °C). These results suggest that the shell of P. fucata martensii could grow well at locations with greater abundance of food and adequate water temperatures (20–26 °C), resulting in a longer growing season. 相似文献
17.
ABSTRACT: A method of filtering logbook data to obtain estimates of catch per unit effort (CPUE) for sharks has been proposed which simultaneously addresses the issues of under-reporting and the lack of species-specific catch records in historical data. Logbook catch data from vessels with high shark reporting rates are used to represent catch rates for the abundant blue shark Prionace glauca and low reporting vessels' data are used for the main commercially valuable species, the shortfin mako Isurus oxyrinchus . Logbook reporting rate filter (RRF) levels are evaluated through analytical and model-based comparisons to species-specific logbook records available since 1994 and shipboard observer data. At the high reporting rates, the ≥ 80% filter avoids large numbers of false zeros and provides the best fit to observer data for blue shark. At the low reporting rates, the ≤ 40% filter best matches the observer data for makos, but this filter level includes large numbers of false zeros and sharks of other species. The ≤ 20% filter produces a dataset that is better targeted to mako catches but considerably under-estimates CPUE relative to observer records. For these reasons, other means of estimating mako catch rates are suggested for further research. 相似文献
18.
Effect of plastic-film mulching on leaching of nitrate nitrogen in an upland field converted from paddy 总被引:4,自引:0,他引:4
Tomokazu?HaraguchiEmail author Atsushi?Marui Kozue?Yuge Yoshisuke?Nakano Ken?Mori 《Paddy and Water Environment》2004,2(2):67-72
A lysimeter experiment was conducted to examine the effects of plastic film mulching on the leaching rate of nitrate nitrogen (NO3-N) from chemical fertilizer that was applied to an upland field that had been converted from paddy rice production. Leaching was monitored in two lysimeters filled with sandy loam soil, which contained low soil organic matter content, under different surface mulch conditions. One was mulched only on the ridge (ridge-mulch treatment) and another one was mulched fully, including the furrow, with black plastic film (full-mulch treatment). Chemical fertilizer was mixed into the top 0.2 m of soil in the two lysimeters before installing the mulch. After transplanting broccoli, the amount of subsurface discharge water and the NO3-N concentrations in the discharge water were measured every day. Larger NO3-N discharges occurred in the ridge-mulch treatment for three days after heavy rainfalls in which cumulative precipitation exceeded 10 mm, and the daily NO3-N load was twice as large as the full-mulch treatment. The differences in the amount of subsurface discharge water and NO3-N discharged between treatments were not significant when there was no rainfall. Cumulative NO3-N loads for the ridge- and full-mulch treatment during the last month of the experimental period were 0.246 and 0.195 g m–2, respectively. The effect of mulching on the reduction of NO3-N discharge rate was higher for the full-mulch treatment. This result showed that a plastic-film mulching system would be effective as an appropriate fertilizer management to reduce nitrate-leaching losses. 相似文献
19.
Eric G. Mworia Takashi Yoshikawa Naoki Yokotani Tetsuo Fukuda Katsuhiko Suezawa Koichiro Ushijima Ryohei Nakano Yasutaka Kubo 《Postharvest Biology and Technology》2010,55(2):108-113
Ethylene biosynthesis in kiwifruit, Actinidia chinensis ‘Sanuki Gold’ was characterized using propylene, an ethylene analog, and 1-methylcyclopropene (1-MCP), an inhibitor of ethylene perception. In fruit harvested between a young stage (66 days after pollination) (DAP) and an early commercial harvesting stage (143 DAP), 2 days of exposure to propylene were sufficient to initiate ethylene biosynthesis while in fruit harvested at commercial harvesting stage (154 DAP), 4 days of propylene treatment were required. This observation suggests that response of ethylene biosynthesis to propylene treatment in kiwifruit declined with fruit maturity. Propylene treatment resulted in up-regulated expression of AC-ACO1, AC-ACO2, AC-SAM1 and AC-SAM2, prior to the induction of AC-ACS1 and ethylene production, confirming that AC-ACS1 is the rate limiting step in ethylene biosynthesis in kiwifruit. Treatment of fruit with more than 5 μL L?1 of 1-MCP after the induction of ethylene production subsequently suppressed ethylene production and expression of ethylene biosynthesis genes. Treatment of fruit with 1-MCP at harvest followed with propylene treatment delayed the induction of ethylene production and AC-ACS1 expression for 5 days. These observations suggest that in ripening kiwifruit, ethylene biosynthesis is regulated by positive feedback mechanism and that 1-MCP treatment at harvest effectively delays ethylene production by 5 days. 相似文献
20.
Edamura K Kuriyama K Kato K Nakano R Teshima K Asano K Sato T Tanaka S 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2012,74(7):923-927
We examined the proliferation capacity and neuronal differentiation potency of canine bone marrow stromal cells (BMSCs). In addition, the microstructures of neuron-like cells after neuronal differentiation were observed under a scanning electron microscope. Canine BMSCs grew to confluency at 10.0 ± 2.5 days, and 3.8 ± 2.1 × 10(6) BMSCs were collected in one passage. Approximately 65% of canine BMSCs changed to neuron-like morphology after neuronal differentiation, and nearly all neuron-like cells stained positive against neuron-specific enolase. In addition, microstructures such as the cellular organelles, filaments and growth cones of these cells bore a close resemblance to those of the original mature neurons. These results suggested that canine BMSCs might be capable of differentiating into neurons. 相似文献