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31.
Investigation of lactic acid bacterial strains for meat fermentation and the product's antioxidant and angiotensin‐I‐converting‐enzyme inhibitory activities 下载免费PDF全文
Shiro Takeda Hisashi Matsufuji Koji Nakade Shin‐ichi Takenoyama Abdulatef Ahhmed Ryoichi Sakata Satoshi Kawahara Michio Muguruma 《Animal Science Journal》2017,88(3):507-516
In the lactic acid bacteria (LAB) strains screened from our LAB collection, Lactobacillus (L.) sakei strain no. 23 and L. curvatus strain no. 28 degraded meat protein and tolerated salt and nitrite in vitro. Fermented sausages inoculated strains no. 23 and no. 28 showed not only favorable increases in viable LAB counts and reduced pH, but also the degradation of meat protein. The sausages fermented with these strains showed significantly higher antioxidant activity than those without LAB or fermented by each LAB type strain. Angiotensin‐I‐converting‐enzyme (ACE) inhibitory activity was also significantly higher in the sausages fermented with strain no. 23 than in those fermented with the type strain. Higher ACE inhibitory activity was also observed in the sausages fermented with strain no. 28, but did not differ significantly from those with the type strain. An analysis of the proteolysis and degradation products formed by each LAB in sausages suggested that those bioactivities yielded fermentation products such as peptides. Therefore, LAB starters that can adequately ferment meat, such as strains no. 23 and no. 28, should contribute to the production of bioactive compounds in meat products. 相似文献
32.
Tatsuya Nakayama Michio Jinnai Ryuji Kawahara Khong Thi Diep Nguyen Nam Thang Tran Thi Hoa Le Kieu Hanh Pham Ngoc Khai Yoshinori Sumimura Yoshimasa Yamamoto 《Tropical animal health and production》2017,49(1):31-37
Reports of livestock infections with extended-spectrum beta-lactamase-producing Escherichia coli (ESBL-E) are increasing. Based on interviews conducted over a 6-month period, we found that veterinarians in the Vietnamese province of Thai Binh prefer to prescribe colistin-based drugs (CBD) in chicken farms. We aimed to clarify whether CBD use selects for strains of colistin-resistant ESBL-E. With the cooperation of seven local households, we detected ESBL-E in chickens’ feces after treating chickens with CBD. Phylogenetic groupings and the presence of CTX-M/AmpC genes were determined, and the multi-antibiotic susceptibility of isolates was analyzed. Our results showed that ESBL-E presented in seven chickens’ feces from two households. Seventy-two percent of ESBL-E isolates harbored CTX-M9 and the phylogenetic group A; the colistin minimum inhibitory concentration (MIC) of all isolated ESBL-E ranged from 0.064 to 1 μg mL?1. Moreover, ESBL-E isolates were used to experimentally select for colistin resistance, and the effect of commercial CBD on ESBL-E was investigated. The results showed that an ESBL-E strain with a colistin MIC of 4 μg mL?1 was able to grow in media with CBD. Although CBD treatment was effective, in vitro experiments demonstrated that ESBL-E can easily acquire colistin resistance. Therefore, restrictions on colistin use are necessary to prevent the emergence of colistin-resistant bacteria. 相似文献
33.
Nitrous oxide evolved from soil covered with plastic mulch film in horticultural field 总被引:1,自引:0,他引:1
Seiichi Nishimura Michio Komada Masako Takebe Seiichiro Yonemura Naoto Kato 《Biology and Fertility of Soils》2012,48(7):787-795
Soil solarization practice, in which soil is covered with plastic mulch film and exposed to high temperature prior to crop cultivation, is expected to be an effective method for reducing weeds and pathogenic microorganisms without using agricultural chemicals. Although the production of nitrous oxide (N2O), a major greenhouse gas, is enhanced in fertilized soil covered with plastic mulch films, its transport route to the atmosphere has not been sufficiently elucidated to date. In this study, we investigated the N2O evolution from plastic-mulch-film-covered agricultural soil. In a horticultural field where ridge soil was covered with a plastic mulch film after fertilization, we observed significant N2O flux from the soil surface of the unfertilized furrow between the ridges, indicating the horizontal diffusion of N2O from the ridge soil covered with the mulch film to the adjacent furrow soil surface. On the other hand, the measurement of the permeance (permeation coefficient) of the plastic mulch film for gaseous N2O by laboratory experiment revealed that N2O gradually permeated the mulch film; the permeance increased exponentially with an increase in ambient temperature, indicating possible N2O emission by permeation through the mulch film under field conditions. In winter, the amount of N2O emission by permeation through the mulch film was estimated to be lower than that emitted from the furrow soil surface, and it was lower than that in summer. On the other hand, it was estimated to be much higher in summer owing to the higher permeance of the film at high temperatures. 相似文献
34.
To raise more rice in Japan we have placed much fertilizers in the fields, thus the soils often have been degraded by the leaching of essential elements including Fe to such a extent as rice roots are injured by the H2S produced by the reduction of sulphates. It has been encouraged by law to place non-sulphate fertilizers and iron compounds in these fields. 相似文献
35.
The effect of rice straw on the composition of volatile soil gas and microflora in the tropical paddy field was studied with and without fertilizer application. The volatile soil gas most abundantly found in plots with rice straw was methane followed by other gases, nitrogen, oxygen and carbon dioxide during the early stage of rice growth, while nitrogen predominated in later stages. The loss of soil nitrogen through volatilization increased following phosphorus application as well as rice straw application as compared with that in the control plot. In the former case, the enhancement of decomposition of organic-N was assumed to be due to the increase in population of cellulose decomposer. Rice straw application with or without N-fertilizer increased methane gas formation by 27 to 63 times as compared with the phosphorus plot and the peak of its formation was found 5 to 7 weeks after rice straw application. However methane formation in the control plot was very low and was found only 5 to 9 weeks after flooding. Rice straw application usually increased the number of various groups of microorganisms along with contributing to the transformation of organic-N to N2 gas. But the stimulating effect was chiefly observed in the population of Azotobacter. 相似文献
36.
The effects of five polybrominated diphenol ethers from a Marine Sponge, Phyllospongia dendyi, on the relative plating efficiencies in V79 cells and the cell proliferation and IL-8 production in PMA-stimulated HL-60 cells were examined. Three compounds, possessing two phenol units, were reported to inhibit the assembly of microtubule proteins and showed the inhibition of colony formation of V79 cells and increase in IL-8 production. Interestingly, a monomethoxy compound exhibited the stronger activity than the three active compounds in both bioassays. This compound did not inhibit the assembly of microtubule proteins. A dimethoxy compound was not active in either bioassays. In these experimental conditions, the biological activities were not high, but in future, these compounds will be expected to be made stronger by structural modifications. 相似文献
37.
Taiko Oda Jong-Soo Lee Yuta Sato Yasuaki Kabe Satoshi Sakamoto Hiroshi Handa Remy E. P. Mangindaan Michio Namikoshi 《Marine drugs》2009,7(4):589-599
N,N-Didesmethylgrossularine-1 (DDMG-1), a compound with a rare α-carboline structure, was isolated from an Indonesian ascidian Polycarpa aurata as responsible for the observed inhibitory activity against TNF-α production in lipopolysaccharide-stimulated murine macrophage-like RAW264.7 cells. DDMG-1 inhibited the mRNA level of mTNF-α, IκB-α degradation, and binding of NF-κB to the target DNA site in LPS-stimulated RAW 264.7 cells. Moreover, DDMG-1 had an inhibitory effect on the production of IL-8, which is produced in CD14+-THP-1 cells stimulated by LPS. DDMG-1 is thus a promising drug candidate lead compound for the treatment of chronic inflammatory diseases, such as rheumatoid arthritis. 相似文献
38.
Hara Y Nezu Y Harada Y Hasegawa D Fujita M Orima H Tagawa M 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2002,64(9):863-866
An intradural tumor in the upper cervical region was found in a dog with quadriparesis and chronic respiratory acidosis. Surgical removal of the tumor in the atlas and intraoperative radiotherapy were attempted. The tumor was histologically diagnosed as a neural glioma. A preoperative acid-base disturbance was dramatically improved after surgery. The clinical changes appeared in this case suggest that compression of the spinal cord at this region may cause paralysis of the respiratory muscles and secondarily result in chronic respiratory acidosis following the respiratory insufficiency. 相似文献
39.
Hasegawa D Fujita M Nakamura S Takahashi K Orima H 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2002,64(3):277-279
A Shetland sheepdog with epilepsy refractory to antiepileptic drugs was brought to the division of Veterinary Radiology at Nippon Veterinary and Animal Science University. Scalp electroencephalography and computed tomography was performed, but no abnormality was detected in either examination. To obtain detailed information, electrodes were implanted on the dura mater, and the electrocorticogram (ECoG) was recorded. In the ECoG, sporadic spikes were detected in the left parietal region, suggesting the presence of the epileptic focus in this region. After the dog's death, abnormalities of gyri were found in the region where spikes were detected in the ECoG. On histopathological examination, laminar malacia of the cingulate gyrus was observed. Furthermore, in the hippocampus, neuronal loss of pyramidal cells was observed. 相似文献
40.
Y. Heishima Y. Hori K. Nakamura Y. Yamashita N. Isayama N. Kanno M. Katagi H. Onodera S. Yamano Y. Aramaki 《Journal of Veterinary Cardiology》2018,20(4):234-243