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11.
Julie A. Kiland Hannah M. Terhaar Hannah E. Walleck Nickolas Chen Kyle McDaniel Gillian J. McLellan 《Veterinary ophthalmology》2023,26(5):414-421
Objectives
To determine the accuracy, precision, and clinical applicability of the ICare® TONOVET Plus (TVP) in cats.Animals and Procedures
IOP readings obtained with the TVP were compared to values obtained concurrently with the original TONOVET (TV01) and Tono-Pen Vet™ (TP) in 12 normal cats (24 eyes) and 8 glaucomatous LTBP2-mutant cats (13 eyes) in vivo. Reproducibility of TVP readings was also assessed for three observers in the above cats. The anterior chambers of five different normal cat eyes were cannulated ex vivo. IOP was measured with the TVP, TV01, and TP at manometric IOPs ranging from 5 to 70 mmHg. Data were analyzed by linear regression, ANOVA and Bland–Altman plots. ANOVA was used to assess reproducibility of TVP readings obtained by different observers and an ANCOVA model controlled for variation of individual cats. p < .05 was considered significant.Results
TVP values strongly correlated with TV01 values (y = 1.045x + 1.443, R2 = .9667). The TP significantly underestimated IOP relative to the TVP and TV01, particularly at high IOP. IOP values obtained by 1 observer were significantly higher (~1 mmHg average) compared to the other 2 observers via ANCOVA analysis (p = .0006479 and p = .0203). Relative to manometry, the TVP and TV01 were significantly more accurate (p < .0001) and precise (p < .0070) than the TP in ex vivo eyes.Conclusions
IOP readings obtained with the TVP and TV01 are broadly interchangeable between models and between observers, but subtle differences may be important in a research context. TP readings vastly underestimate high IOP in feline glaucoma. 相似文献12.
1. The present study was undertaken to determine the effects of heat exposure on fertility, semen quality, and semen ion concentrations of broiler breeders classified on sperm quality index (SQI) before heat stress. 2. Cobb males (108) were individually caged in 6 temperature-controlled rooms. Each room contained an equal number of males from each of the 4 SQI population quartiles as follows: best (B), good (G), fair (F), and poor (P). Three rooms were heated to 35 degrees C, and the other three rooms were maintained at a constant 23 degrees C as controls. For each SQI group in each room, 15 Leghorn hens were artificially inseminated (5 x 10(7) sperm/hen) once a week for 8 weeks for fertility observations. 3. Body weight, sperm concentration, SQI, and fertility of P males were lower than in the other three SQI groups. Body temperature of the top three SQI groups was increased by heat exposure, but body temperature was not altered by heat stress in the P group. Fertility, sperm viability, and SQI of the top three SQI groups, but not the P group, was decreased by heat stress. Seminal plasma K+ of P males was lower than that of B males. However, seminal plasma Ca2+ concentration of P males was higher than that of B males. 4. In conclusion, high ambient temperatures had more impact on semen quality and fertility of males in the top 75% of the SQI population than in males in the bottom 25% of the population. In addition, calcium ions (Ca2+) appear to play a major role in heat stress infertility. 相似文献
13.
Landon L. Pierce Dane A. Shuman Daniel A. James Kirk D. Steffensen Ryan Wilson Kyle Winders Adam McDaniel 《Fisheries Management and Ecology》2019,26(3):295-305
The middle Missouri River (MMR; Fort Randall Dam, SD to Gavins Point Dam, NE‐SD) is stocked with hatchery‐reared pallid sturgeon, Scaphirhynchus albus (Forbes and Richardson), from upper Missouri River broodstock to aid recovery of this federally endangered species. Emigration of these fish through Gavins Point Dam restores genetic connectivity that likely existed pre‐impoundment but could lead to outbreeding depression in the future. Recapture data of hatchery‐reared pallid sturgeon stocked in the MMR were evaluated to improve understanding of pallid sturgeon emigration. From 2004 to 2015, 219 emigrants were caught: 4 stocked at age ≥2 years and 215 stocked at age ≤1 year. Emigration of the 2001‐2007 year classes stocked at age 1 was a consistent phenomenon and appeared higher than emigration of year classes stocked at ages 2–3. Little evidence suggested emigration was associated with an unusually high‐water event in 2011. The annual emigration probability of individuals stocked at age 1 estimated from multi‐state mark–recapture models was 0.05 [95% confidence interval = 0.04–0.06] for fish ages ≥1 year. This study suggests that alterations to stocking practices (e.g. stocking age) may affect emigration rates and, therefore, connectivity among pallid sturgeon populations. 相似文献
14.
Giot L Bader JS Brouwer C Chaudhuri A Kuang B Li Y Hao YL Ooi CE Godwin B Vitols E Vijayadamodar G Pochart P Machineni H Welsh M Kong Y Zerhusen B Malcolm R Varrone Z Collis A Minto M Burgess S McDaniel L Stimpson E Spriggs F Williams J Neurath K Ioime N Agee M Voss E Furtak K Renzulli R Aanensen N Carrolla S Bickelhaupt E Lazovatsky Y DaSilva A Zhong J Stanyon CA Finley RL White KP Braverman M Jarvie T Gold S Leach M Knight J Shimkets RA McKenna MP Chant J Rothberg JM 《Science (New York, N.Y.)》2003,302(5651):1727-1736
15.
Variation in cellular biochemical functions controlled by cytoplasmic genes was studied in relation to phenotypic differences between progeny of reciprocal hybrid female mice. Least squares procedures were used to test for differences in mitochondrial respiratory metabolism and in capacity for ATP synthesis, and differences in growth of progeny of hybrid dams. Under identical nuclear influences, mitochondria of A/J and C57BL/6J cytoplasms differed (P less than .10 to P less than .01) from those of BALB/cJ cytoplasm in energy conservation. No differences were detected in mitochondrial efficiency between BALB/cJ cytoplasm evaluated in different nuclear environments. Three-way cross progeny of C57BL/6J x BALB/cJ reciprocal hybrid females mated to DBA/2J males differed (P less than .05) in litter weight at weaning and 1 wk and 2 wk postweaning. The F2 progeny of reciprocal C57BL/6J x BALB/cJ dams and F2 and three-way cross progeny of reciprocal A/J x BALB/cJ dams did not differ in weight at any age measured. Across all genotypes of dam, rank correlations of mitochondrial traits with F2 litter weights were nonsignificant. Observed variation in mitochondrial functions partially controlled by cytoplasmic genes did not limit mouse growth under these experimental conditions. 相似文献
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18.
Pusterla N Kass PH Mapes S Johnson C Barnett DC Vaala W Gutierrez C McDaniel R Whitehead B Manning J 《The Veterinary record》2011,169(1):12
The prevalence and epidemiology of important viral (equine influenza virus [EIV], equine herpesvirus type 1 [EHV-1] and EHV-4) and bacterial (Streptococcus equi subspecies equi) respiratory pathogens shed by horses presented to equine veterinarians with upper respiratory tract signs and/or acute febrile neurological disease were studied. Veterinarians from throughout the USA were enrolled in a surveillance programme and were asked to collect blood and nasal secretions from equine cases with acute infectious upper respiratory tract disease and/or acute onset of neurological disease. A questionnaire was used to collect information pertaining to each case and its clinical signs. Samples were tested by real-time PCR for the presence of EHV-1, EHV-4, EIV and S equi subspecies equi. A total of 761 horses, mules and donkeys were enrolled in the surveillance programme over a 24-month study period. In total, 201 (26.4 per cent) index cases tested PCR-positive for one or more of the four pathogens. The highest detection rate was for EHV-4 (82 cases), followed by EIV (60 cases), S equi subspecies equi (49 cases) and EHV-1 (23 cases). There were 15 horses with double infections and one horse with a triple infection. The detection rate by PCR for the different pathogens varied with season and with the age, breed, sex and use of the animal. 相似文献
19.
S A Fleming E L Hunt C Brownie A Rakes B McDaniel 《American journal of veterinary research》1992,53(2):222-224
Samples of serum and urine were obtained simultaneously from 56 healthy lactating cows to determine ranges of fractional excretion (FE) of calcium (Ca), phosphate (PO4), magnesium (Mg), sodium (Na), potassium (K), and chloride (Cl). Samples were obtained at 3 stages of lactation: period 1 = 1 to 7 days, 2 = 83 to 112 days, and 3 = 175 to 197 days. The FE of electrolytes were significantly different among periods 1, 2, and 3 for Ca (P less than 0.001), PO4 (P less than 0.025) and Mg (P less than 0.025), but were not significantly different for Na, K, and Cl. Least squares mean FE of Ca was lowest in period 1 and not significantly different for periods 2 and 3, whereas mean FE values for PO4 and Mg were highest in period 2 and not significantly different for periods 1 and 3. The mean FE values of Na, K, and Cl did not change with stage of lactation. Age and category of milk production (high, medium, and low) did not influence the FE values of the electrolytes. 相似文献
20.
Peebles ED Kidd MT McDaniel CD Tanksley JP Parker HM Corzo A Woodworth JC 《British poultry science》2007,48(3):299-307
1. Ross 308 broiler breeder hens were given diets containing 0 or 25 mg L-carnitine/kg (8 replications per treatment) from 21 weeks of age. 2. Hens were inseminated with semen from Ross broiler breeder males. In a common facility, subsequent progeny hatchability and embryonic mortality at 25, 30, 32, and 38 weeks of breeder age were evaluated. 3. Subsequent egg component weights, incubational egg water loss, progeny embryo growth, and embryo, yolk sac and liver composition through 18 d of incubation at 27, 32, and 38 weeks of breeder age were evaluated. 4. Calculated additions of L-carnitine were in agreement with analysed contents of 3.5 and 31.1 mg free L-carnitine/kg of diet, respectively, and total L-carnitine concentrations increased by 48.6, 21.7, and 10.0% in 0-d yolk, 18-d yolk sac, and 18-d liver samples, respectively, due to the addition of dietary L-carnitine. 5. Supplemental L-carnitine resulted in increased (0.6%) relative 0-d egg yolk weight across weeks 27, 32, and 38, and reduced (0.38%) 18-d yolk sac palmitoleic acid concentration at week 27 without altering embryogenesis. 6. In conclusion, dietary L-carnitine (25 mg/kg of the diet) was deposited in the yolks of broiler breeder hens and was subsequently transferred to the embryonic liver via yolk sac absorption through 18 d of incubation. Furthermore, dietary L-carnitine supplementation increased ovarian follicle yolk deposition in 27-, 32-, and 38-week-old breeder hens, and influenced yolk sac fatty acid beta-oxidation in embryos from 27-week-old breeder hens causing yolk sac palmitoleic acid concentrations to be reduced by 18 d of incubation. 相似文献