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31.
Antibiotic Resistance Genes in the Human-Impacted Environment: A One Health Perspective 总被引:1,自引:0,他引:1
James M. TIEDJE WANG Fang Clia M. MANAIA Marko VIRTA SHENG Hongjie MA Liping ZHANG Tong Edward TOPP 《土壤圈》2019,29(3):273-282
Antibiotic resistance and its environmental component are gaining more attention as part of combating the growing healthcare crisis. The One Health framework, promulgated by many global health agencies, recognizes that antimicrobial resistance is a truly inter-domain problem in which human health, animal agriculture, and the environment are the core and interrelated components. This prospectus presents the status and issues relevant to the environmental component of antibiotic resistance, namely, the needs for advancing surveillance methodology:the environmental reservoirs and sources of resistance, namely, urban wastewater treatment plants, aquaculture production systems, soil receiving manure and biosolid, and the atmosphere which includes longer range dispersal. Recently, much work has been done describing antibiotic resistance genes in various environments; now quantitative, mechanistic, and hypothesis-driven studies are needed to identify practices that reduce real risks and maintain the effectiveness of our current antibiotics as long as possible. Advanced deployable detection methods for antibiotic resistance in diverse environmental samples are needed in order to provide the surveillance information to identify risks and define barriers that can reduce risks. Also needed are practices that reduce antibiotic use and thereby reduce selection for resistance, as well as practices that limit the dispersal of or destroy antibiotic-resistant bacteria or their resistance genes that are feasible for these varied environmental domains. 相似文献
32.
Marko Vinceković Luna Maslov Bandić Slaven Jurić Nenad Jalšenjak Ana Čaić Irena Živičnjak 《Journal of plant nutrition》2019,42(6):543-558
An overview of a research on Vitis vinifera plants treated with a chemical (calcium and magnesium ions) and biological (Trichoderma viride) agents simultaneously loaded in alginate microspheres was presented. Microspheres were applied at two growth stages: before flowering and berries pea-size. Physicochemical characteristics of leaves after the two growth stages and grapes were measured in terms of bioactive components content and antioxidant activity. After the treatments, vine leaves reached a significant increase in almost all measured parameters (polyphenols, antioxidant capacity, β-carotene, and chlorophyll) compared to the control. The highest total chlorophyll content was found after the treatment with microspheres containing Mg2+/Ca2+ cations, and T. viride. The treatments enhanced Vitis vinifera leaves in terms of bioactive potential and can be further used as a functional food. As compared to the control, somewhat elevated values of total polyphenols and antioxidant activity were found on the grape samples. 相似文献
33.
Darja Kocjan Ačko Marko Flajšman 《Acta Agriculturae Scandinavica, Section B - Plant Soil Science》2019,69(4):317-323
In plants, apical dominance prevents the development of lateral shoots. It can be overwhelmed by apical bud defoliation, allowing numerous lateral buds to develop into more lateral branches carrying more fruits and possibly increasing seed yield. This study tested this hypothesis on five hemp (Cannabis sativa L.) cultivars in a 2-year field experiment. In comparison to the intact ones, the defoliated plants developed several lateral shoots. The hemp seed yield was significantly influenced by the year of production, the apical bud removal, and the cultivar. The average two-year seed yield of the defoliated plants (715?±?47?kg/ha) was significantly higher than the yield of the intact plants (568?±?35?kg/ha). Absolutely the greatest effect of apical bud removal on the seed yield was observed for the cultivar ‘Novosadska konoplja’, where increase was 225?kg/ha (25%); a slightly smaller difference occurred for the cultivar ‘Uniko-B’ (183?kg; 30%), followed by ‘Juso-11’ (140?kg/ha; 27%) and ‘Bialobrzeskie’ (128?kg/ha; 29). Cultivar ‘Beniko’ presented the smallest difference with apical bud removal – 58?kg/ha (15%) yield increase We maintain that hemp producers can achieve a larger seed yield not only by selecting an appropriate cultivar and row distance but also by removing apical buds. 相似文献
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Polycystic kidney disease (PKD) is an inherited autosomal kidney disease which is most commonly identified in Persian and Persian related cats. Positive cats have multiple cysts of various sizes that occur in the renal cortex and medulla and occasionally in other abdominal organs. PKD often leads to renal failure which occurs from mid to late in life. Renal cysts can be diagnosed ultrasonographically after 7 weeks of age by an experienced ultrasonographer and a high resolution machine. However, ultrasonography is now being replaced by genetic screening. A total of 340 cats of variable breeds aged from 5 months to 18 years were ultrasonographically examined in the past 7 years at the University Veterinary Small Animal Clinic. Of these, 13.8% were PKD positive with very high prevalence in Persian cats (36%). There was no sex predilection identified. The C>A transversion at position 3284 on exon 29 of PKD1 gene, resulting in a stop mutation has been identified in the heterozygous state in eight affected cats examined (Persian breed). All heterozygous cats were also ultrasonographically positive. 相似文献
36.
The antimicrobial activity of Bryum argenteum ethanol extracts was evaluated by microdilution method against four bacterial (Escherichia coli, Bacillus subtilis, Micrococcus luteus and Staphilococcus aureus) and four fungal species (Aspergillus niger, Penicillium ochrochloron, Candida albicans and Trichophyton mentagrophyes). All the investigated ethanol extracts have been proved to be active against all bacteria and fungi tested. 相似文献
37.
Vesna Poleksić Marko Stanković Zoran Marković Renata Relić Nada Lakić Zorka Dulić Božidar Rašković 《Aquaculture International》2014,22(1):289-298
The study was carried out to examine morphological and physiological effects of different levels of fat in compound extruded feed for carp. A 90 days experiment was performed in tanks with water flow 0.34 L min?1, stocked each with 29 specimens of carp, average weight 15.4 ± 4.2 g. The fish was fed 3 diets containing 38 % protein and 8, 12 or 16 % of fat (feed L8, L12, and L16, respectively). Body weight gain, specific growth rate, food conversion ratio, feed efficiency ratio, condition factor, liver and intestine histology and morphometry and some blood biochemical parameters were analysed. At the end of the experiment, a difference was established between the fish fed L8 feed compared to carp fed L12 and L16 feed for all growth parameters. For several other parameters, nuclear area of hepatocytes, nuclear/cytoplasm ratio, enterocytes height and intestinal folds’ length, a difference between carp fed feed L8 compared to feed L16 was found. The histological analysis revealed that normal structure of the liver and intestine prevailed, but changes were observed regardless of the diet type. In the hepatopancreas, more prominent changes were found around pancreatic tissue—particularly, increased number and size of adipocytes. Although blood biochemical parameters were within normal values, a difference between L8 and L16 diet-fed carp was found for plasma levels of triglycerides and total proteins. According to the results obtained in this study, the best results were achieved using a feed with 8 % fat. 相似文献
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39.
Copper-Catalyzed Oxidation of Alcohols to Aldehydes and Ketones: An Efficient, Aerobic Alternative 总被引:1,自引:0,他引:1
An efficient, copper-based catalyst has been discovered that oxidizes a wide range of alcohols into aldehydes and ketones under mild conditions. This catalytic system utilizes oxygen or air as the ultimate, stoichiometric oxidant, producing water as the only by-product. 相似文献
40.
Growth regulation of human melanocytes: mitogenic factors in extracts of melanoma, astrocytoma, and fibroblast cell lines 总被引:5,自引:0,他引:5
Melanocytes derived from fetal or adult skin do not propagate in vitro unless cultured in the presence of factors such as 12-O-tetradecanoylphorbol 13-acetate (TPA). In a search for physiological factors regulating the growth of melanocytes, extracts of various cultured cell types were tested. Factors produced by melanoma and astrocytoma cell lines support continued proliferation of melanocytes in the absence of TPA. WI-38, a fibroblast cell line derived from human embryonic lung, was the most active source of melanocyte growth factors. No melanocyte growth-promoting activity was found in extracts of cultured neuroblastoma, renal cancer, normal keratinocytes, or renal epithelium. Nerve growth factor, epidermal growth factor, melanocyte-stimulating hormone, transforming growth factor-beta, and platelet-derived growth factor did not have growth-promoting activity for melanocytes. The presence of melanocyte growth factors and TPA together resulted in the strongest mitogenic activity for melanocytes, permitting the recovery (at 20 days) of 4 to 20 times as many cells as in growth factor or TPA alone. 相似文献