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排序方式: 共有117条查询结果,搜索用时 15 毫秒
81.
82.
Julie Corriveau Eric van Bochove Martine M. Savard Daniel Cluis Daniel Paradis 《Water, air, and soil pollution》2010,206(1-4):335-347
This study is the first to report nitrite occurrence and variability in surface water across an agricultural watershed in the province of Quebec, Canada. Nitrite (NO2 ?) concentrations were monitored across a 2.4 km2 watershed during 2 years. Water samples were collected at the outlet from April to November and in three contrasted stream branches (six stations) during three hydrological regimes (summer low water levels, fall recharge, and snowmelt). Our study clearly demonstrates that NO2 ? levels observed at the outlet are not representative of NO2 ? variability across the micro-watershed. Surface water collected in cropped areas presents high NO2 ? concentrations during summer low water levels, often exceeding guidelines for aquatic life, with NO2 ? means ranging from 0.022 to 0.107 mg N L?1 and maximum value reaching 0.156 mg N L?1. Furthermore, the two stream branches in cropped area have demonstrated significant differences in NO2 ? concentrations and other water quality parameters. The importance of groundwater discharge to streams in the micro-watershed Bras d’Henri may potentially generate different in-stream sources of NO2 ? and water quality parameters. However, further studies are essential to determine sources and processes related to in-stream NO2 ? peaks. 相似文献
83.
Somatic embryos were obtained from young, isolated cotyledons of Picea abies. A bud-inductive treatment for one week before transfer to a callus induction medium, resulted in a tenfold increase in the percentage of cotyledons in which embryonic tissues could be induced. The degree of expression of somatic embryogeny depends on whether cotyledons are first subjected to a callus-inducing medium or first exposed to a cytokinin treatment followed by a callus-inducing medium. It is hypothesized that two populations of cells exist, both with the inherent potential of becoming embryogenic after treatment with plant growth regulators. 相似文献
84.
Picard C Puel A Bonnet M Ku CL Bustamante J Yang K Soudais C Dupuis S Feinberg J Fieschi C Elbim C Hitchcock R Lammas D Davies G Al-Ghonaium A Al-Rayes H Al-Jumaah S Al-Hajjar S Al-Mohsen IZ Frayha HH Rucker R Hawn TR Aderem A Tufenkeji H Haraguchi S Day NK Good RA Gougerot-Pocidalo MA Ozinsky A Casanova JL 《Science (New York, N.Y.)》2003,299(5615):2076-2079
Members of the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) superfamily share an intracytoplasmic Toll-IL-1 receptor (TIR) domain, which mediates recruitment of the interleukin-1 receptor-associated kinase (IRAK) complex via TIR-containing adapter molecules. We describe three unrelated children with inherited IRAK-4 deficiency. Their blood and fibroblast cells did not activate nuclear factor kappaB and mitogen-activated protein kinase (MAPK) and failed to induce downstream cytokines in response to any of the known ligands of TIR-bearing receptors. The otherwise healthy children developed infections caused by pyogenic bacteria. These findings suggest that, in humans, the TIR-IRAK signaling pathway is crucial for protective immunity against specific bacteria but is redundant against most other microorganisms. 相似文献
85.
86.
E Morris H J Seeherman M W O'Callaghan S H Schelling M R Paradis R S Steckel 《Equine veterinary journal》1991,23(5):347-352
The uptake of the bone-seeking radiopharmaceutical 99mTc-MDP by damaged skeletal muscle in horses is evaluated. Twenty-four hours following strenuous exercise, 109 racehorses with a history of inadequate athletic performance and subtle lameness were imaged using scintigraphic techniques. Ten horses (9.2 per cent) demonstrated abnormal uptake of the radioisotope within skeletal muscles. A muscle biopsy from one of these horses confirmed that the muscles with increased scintigraphic activity had histologic evidence of rhabdomyolysis. This technique allows localisation and relative quantification of muscle damage and is a valuable aid in the evaluation of the athletic horse. 相似文献
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88.
Bodinier M Legoux MA Pineau F Triballeau S Segain JP Brossard C Denery-Papini S 《Journal of agricultural and food chemistry》2007,55(11):4576-4583
Because intestinal absorption of food protein can trigger an allergic reaction, the effect of wheat proteins on intestinal epithelial cell permeability was evaluated and the abilities of these proteins in native or pepsin-hydrolyzed state to cross the epithelial cell monolayer were compared. Enterocytic monolayers were established by culturing Caco-2 cells, a model of enterocytes, on permeable supports that separate the apical and basal compartments. Proteins were added into the apical compartment, and the transepithelial resistance (TER) was measured; proteins that crossed the cell monolayer were detected in the basal medium by ELISA. Wheat proteins did not alter the cell monolayer. TER and Caco-2 cell viability were conserved, and the passage of dextran was prevented. Native and pepsin-hydrolyzed forms of omega5-gliadin and lipid transfer proteins were detected in the basal medium. The results suggest that these two major allergens in food allergy to wheat were able to cross the cell monolayer by the transcellular route. 相似文献
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90.
Use of recombinant human thyroid-stimulating hormone for thyrotropin stimulation test in euthyroid dogs 下载免费PDF全文
Sauvé F Paradis M 《The Canadian veterinary journal. La revue veterinaire canadienne》2000,41(3):215-219
The purpose of this study was to evaluate the effects of the recombinant human thyroid-stimulating hormone (rhTSH) on serum total thyroxine (TT4) concentration in euthyroid dogs. Six healthy beagle dogs were used in each of the 3 phases of this study. Phase I: thyroid-stimulating hormone response tests were performed by using a total dose of 25 micrograms, 50 micrograms, and 100 micrograms of rhTSH, administered intravenously. Phases II and III: thyroid-stimulating hormone response tests were performed by using 50 micrograms of rhTSH administered by intramuscular and subcutaneous routes, respectively. In each phase and following all the administered doses of rhTSH, an increase in the serum TT4 concentration was noted, although it was not always significant. For phase I, there was a significant increase in serum TT4 concentrations. Based on this study, 50 micrograms was judged to be the optimal intravenous dose of rhTSH. For phases II and III, there was no significant increase in serum TT4 after the administration of rhTSH. Results of this study suggest that rhTSH could be a good substitute for bovine TSH, when used by the intravenous route, for the TSH stimulation test in dogs. Further studies are required to confirm its clinical usefulness. 相似文献