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A spontaneous neurological disease in cats characterized by behavioural and motor disturbances was reported in Sweden by Kronevi et al (1974). Generally, the animals showed no gross pathological lesions. Detailed neuro-pathological investigation revealed mononuclear perivascular cuffing and gliosis throughout the brain and spinal cord consistent with a non-suppurative meningoencephalomyelitis. After this first report, the disease has become recognized in different parts of Sweden, preferably Uppland and the area around Lake Mälaren, and is referred to as “staggering disease” of cats. The clinical manifestation of the disease includes hindleg ataxia and paresis (Fig. 1), inability to retract the claws (Fig. 2), mental changes, anorexia, increased salivation, hypersensitivity to sound and light, hyperesthesia, impaired vision and seizures (Kronevi et al 1974, Ström et al 1992). Despite treatment with antimicrobial drugs and corticosteroids most cats deteriorate and die or have to be euthanised after 1-4 weeks of illness. 相似文献
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R P Crawford J D Huber R B Sanders 《Journal of the American Veterinary Medical Association》1986,189(5):547-549
Fifty-six heifers were weaned from dams that were card-test positive for brucellosis. Forty-four dams were positive by rivanol and complement-fixation tests and Brucella abortus field strain was isolated from 14. Numbers of expected pregnancies following natural breeding and numbers of viable calves produced were not reduced in the heifers. Persistent B abortus infection was documented in 2 of 37 parturient heifers from reactor dams. The frequency of infection was 1 of 10 in strain 19-vaccinated heifers, and 1 of 27 in nonvaccinated heifers. The 2 persistently infected heifers had atypical serologic reaction patterns before normal parturitions. 相似文献
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Ludwig A Gatineau S Reynaud MC Cadoré JL Bourdoiseau G 《Veterinary journal (London, England : 1997)》2005,169(3):155-461
This aetiological study of guttural pouch mycosis (GPM) in the horse was based on the retrospective study of 21 horses brought into the National Veterinary School of Lyon (France) between 1998 and 2002. Biopsies were taken from the lesions caused by GPM during endoscopic examination. In 87% of the cases, direct examination gave positive results, whereas 43% of the cultures were found to be negative. The main fungi observed were Aspergillus fumigatus (in three cases), A. versicolor (in two cases, together with other fungi), and A. nidulans and A. niger (one case each). In six cases, the Aspergillus species could not be identified. In two cases, cleistothecia and/or Hulle cells were observed. In three cases, fungi other than Aspergillus were seen, mixed or not with Aspergillus. These results underline the importance of Aspergillus fumigatus in the development of GPM in horses. 相似文献