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91.
92.
Giovannoni SJ Tripp HJ Givan S Podar M Vergin KL Baptista D Bibbs L Eads J Richardson TH Noordewier M Rappé MS Short JM Carrington JC Mathur EJ 《Science (New York, N.Y.)》2005,309(5738):1242-1245
The SAR11 clade consists of very small, heterotrophic marine alpha-proteobacteria that are found throughout the oceans, where they account for about 25% of all microbial cells. Pelagibacter ubique, the first cultured member of this clade, has the smallest genome and encodes the smallest number of predicted open reading frames known for a free-living microorganism. In contrast to parasitic bacteria and archaea with small genomes, P. ubique has complete biosynthetic pathways for all 20 amino acids and all but a few cofactors. P. ubique has no pseudogenes, introns, transposons, extrachromosomal elements, or inteins; few paralogs; and the shortest intergenic spacers yet observed for any cell. 相似文献
93.
RNA silencing genes control de novo DNA methylation 总被引:1,自引:0,他引:1
Chan SW Zilberman D Xie Z Johansen LK Carrington JC Jacobsen SE 《Science (New York, N.Y.)》2004,303(5662):1336
94.
Murphy WJ Larkin DM Everts-van der Wind A Bourque G Tesler G Auvil L Beever JE Chowdhary BP Galibert F Gatzke L Hitte C Meyers SN Milan D Ostrander EA Pape G Parker HG Raudsepp T Rogatcheva MB Schook LB Skow LC Welge M Womack JE O'brien SJ Pevzner PA Lewin HA 《Science (New York, N.Y.)》2005,309(5734):613-617
The genome organizations of eight phylogenetically distinct species from five mammalian orders were compared in order to address fundamental questions relating to mammalian chromosomal evolution. Rates of chromosome evolution within mammalian orders were found to increase since the Cretaceous-Tertiary boundary. Nearly 20% of chromosome breakpoint regions were reused during mammalian evolution; these reuse sites are also enriched for centromeres. Analysis of gene content in and around evolutionary breakpoint regions revealed increased gene density relative to the genome-wide average. We found that segmental duplications populate the majority of primate-specific breakpoints and often flank inverted chromosome segments, implicating their role in chromosomal rearrangement. 相似文献
95.
Pederson GT Gray ST Woodhouse CA Betancourt JL Fagre DB Littell JS Watson E Luckman BH Graumlich LJ 《Science (New York, N.Y.)》2011,333(6040):332-335
In western North America, snowpack has declined in recent decades, and further losses are projected through the 21st century. Here, we evaluate the uniqueness of recent declines using snowpack reconstructions from 66 tree-ring chronologies in key runoff-generating areas of the Colorado, Columbia, and Missouri River drainages. Over the past millennium, late 20th century snowpack reductions are almost unprecedented in magnitude across the northern Rocky Mountains and in their north-south synchrony across the cordillera. Both the snowpack declines and their synchrony result from unparalleled springtime warming that is due to positive reinforcement of the anthropogenic warming by decadal variability. The increasing role of warming on large-scale snowpack variability and trends foreshadows fundamental impacts on streamflow and water supplies across the western United States. 相似文献
96.
Gelfand MJ Raver JL Nishii L Leslie LM Lun J Lim BC Duan L Almaliach A Ang S Arnadottir J Aycan Z Boehnke K Boski P Cabecinhas R Chan D Chhokar J D'Amato A Ferrer M Fischlmayr IC Fischer R Fülöp M Georgas J Kashima ES Kashima Y Kim K Lempereur A Marquez P Othman R Overlaet B Panagiotopoulou P Peltzer K Perez-Florizno LR Ponomarenko L Realo A Schei V Schmitt M Smith PB Soomro N Szabo E Taveesin N Toyama M Van de Vliert E Vohra N Ward C Yamaguchi S 《Science (New York, N.Y.)》2011,332(6033):1100-1104
With data from 33 nations, we illustrate the differences between cultures that are tight (have many strong norms and a low tolerance of deviant behavior) versus loose (have weak social norms and a high tolerance of deviant behavior). Tightness-looseness is part of a complex, loosely integrated multilevel system that comprises distal ecological and historical threats (e.g., high population density, resource scarcity, a history of territorial conflict, and disease and environmental threats), broad versus narrow socialization in societal institutions (e.g., autocracy, media regulations), the strength of everyday recurring situations, and micro-level psychological affordances (e.g., prevention self-guides, high regulatory strength, need for structure). This research advances knowledge that can foster cross-cultural understanding in a world of increasing global interdependence and has implications for modeling cultural change. 相似文献
97.
The relative importance of litter quality and site heterogeneity on population dynamics of decomposer food webs was investigated in a semi-natural mixed deciduous forest in Denmark. Litterbags containing beech or ash leaves were placed in four plots. Plots were located within gaps and under closed canopies at two topographically different sites, above and below a slope, respectively, to cover variable environmental conditions. Litter was collected after 2, 4 and 9 months of decomposition. Extensive decay prevented analysis of ash after 9 months. Density of bacteria (CFU), active fungal mycelium (FDA), protozoa (MPN) and nematodes were 4-15-fold higher in ash leaves than in beech leaves in accordance with the higher resource quality of ash. Similar effects of site on density of decomposers were evident in both litter types: with some exceptions, decomposers were higher at the low site and stimulated in gaps. Taxonomic diversity of nematodes increased during decomposition and functional diversity of nematodes followed a pattern often encountered, i.e. opportunistic bacterial-feeders were gradually replaced by fungal-feeders and slower growing bacterial-feeders while predators and omnivors peaked at the end of the study period. At the first sampling, where bacterial activity prevailed, the relative abundance of the two dominant bacterial-feeders, Rhabditidae (fast growing) and Plectus spp. (slower growing), depended more on site than litter type. At the second sampling where fungal activity became more important, the proportions of bacterial and fungal-feeding nematodes also depended more on site than on litter type. At the third sampling individual nematode taxa responded differently to site. In summary, we conclude that although litter quality had a major influence on the density of organisms in the decomposer food web, site effects were also detected and nematode functional groups responded more to site than to litter quality early on in the decomposition process. 相似文献
98.
Thompson FE Midthune D Subar AF Kahle LL Schatzkin A Kipnis V 《Public health nutrition》2004,7(8):1097-1105
OBJECTIVES: We describe the methods used to develop and score a 17-item 'screener' designed to estimate intake of fruit and vegetables, percentage energy from fat and fibre. The ability of this screener and a food-frequency questionnaire (FFQ) to measure these exposures is evaluated. DESIGN: Using US national food consumption data, stepwise multiple regression was used to identify the foods to be included on the instrument; multiple regression analysis was used to develop scoring algorithms. The performance of the screener was evaluated in three different studies. Estimates of intakes measured by the screener and the FFQ were compared with true usual intake based on a measurement error model. SETTING: US adult population. SUBJECTS: For development of instrument, n=9323 adults. For testing of instrument, adult men and women in three studies completing multiple 24-hour dietary recalls, FFQ and screeners, n=484, 462 and 416, respectively. RESULTS: Median recalled intakes for examined exposures were generally estimated closely by the screener. In the various validation studies, the correlations between screener estimates and estimated true intake were 0.5-0.8. In general, the performances of the screener and the full FFQ were similar; estimates of attenuation were lower for screeners than for full FFQs. CONCLUSIONS: When coupled with appropriate reference data, the screener approach described may yield useful estimates of intake, for both surveillance and epidemiological purposes. 相似文献
99.
Lisa A. Richman Christopher D. Wren Pamela M. STokes 《Water, air, and soil pollution》1988,37(3-4):465-473
Concerns about Hg contamination of fish have changed in emphasis from Hg-contaminated systems to more remote and apparently unpolluted systems. For remote lakes, a negative relationship between lake pH and Hg in fish has been demonstrated, implying an effect on Hg uptake from lake acidification. Though this relationship was discussed, and hypotheses put forward concerning the possible mechanisms 8 yr ago, the factors regulating Hg uptake by aquatic biota are still poorly understood. Several recent studies have prompted workers to observe that frequently cited concepts about processes affecting Hg accumulation and cycling are in fact over-simplifications. This review attempts to synthesize and clarify the present state of knowledge. We critically evaluate evidence for a number of controlling factors in the context of the concentrations, the chemical species and the biological uptake processes for Hg. The factors include: trophic status and organic content of water, food chain transfer and biomagnification of Hg, organism age and size effects, feeding strategies, biological and chemical methylation, concentration of cations including H+ and Ca2+ and the immediate source of Hg. 相似文献
100.
Brit Lisa Skjelkvåle 《Water, air, and soil pollution》1994,77(1-2):151-167
The sources and mechanisms regulating fluoride (F) in Norwegian lake waters are studied using data from regional surveys of precipitation chemistry, lake water chemistry and bedrock geology. Fluoride concentrations in Norwegian lakes range from < 5 to 560 μg L?1. Fluoride content in the bedrock is the most important factor controlling F levels in lake waters, as shown by significant differences in median value of F concentrations between lakes situated in different geological provinces. There are also weak but significant correlations between F in the lakes and components typical for weathering such as non-marine Ca, Mg, Na and K. The regional picture of F concentration in lake water shows elevated F concentrations in the acidified areas in southern and southeastern Norway compared to other regions of the country with comparable geology. There is a weak but significant correlation between F and SO4, a typical indicator of acidification in surface water. Mass balance calculations in three catchments show that F is retained in soils in pristine areas, while F output exceeds precipitation input in acidified areas. This both demonstrates the strong retention capacity for F in soils and indicates that anthropogenic F added through polluted rain is a minor source of F in surface waters. Fluoride is mobilized in acidifies areas, probably due to complexation with Al. 相似文献