全文获取类型
收费全文 | 514篇 |
免费 | 61篇 |
专业分类
林业 | 24篇 |
农学 | 8篇 |
基础科学 | 2篇 |
77篇 | |
综合类 | 92篇 |
农作物 | 13篇 |
水产渔业 | 51篇 |
畜牧兽医 | 288篇 |
园艺 | 2篇 |
植物保护 | 18篇 |
出版年
2023年 | 6篇 |
2021年 | 12篇 |
2020年 | 15篇 |
2019年 | 8篇 |
2018年 | 17篇 |
2017年 | 21篇 |
2016年 | 25篇 |
2015年 | 11篇 |
2014年 | 13篇 |
2013年 | 22篇 |
2012年 | 30篇 |
2011年 | 29篇 |
2010年 | 11篇 |
2009年 | 34篇 |
2008年 | 26篇 |
2007年 | 27篇 |
2006年 | 28篇 |
2005年 | 24篇 |
2004年 | 29篇 |
2003年 | 18篇 |
2002年 | 22篇 |
2001年 | 10篇 |
2000年 | 5篇 |
1999年 | 9篇 |
1998年 | 7篇 |
1997年 | 6篇 |
1996年 | 3篇 |
1995年 | 8篇 |
1994年 | 4篇 |
1993年 | 5篇 |
1991年 | 7篇 |
1990年 | 4篇 |
1989年 | 6篇 |
1988年 | 6篇 |
1987年 | 3篇 |
1986年 | 5篇 |
1985年 | 4篇 |
1984年 | 6篇 |
1982年 | 2篇 |
1981年 | 3篇 |
1979年 | 2篇 |
1970年 | 2篇 |
1969年 | 2篇 |
1947年 | 2篇 |
1916年 | 3篇 |
1915年 | 2篇 |
1911年 | 4篇 |
1909年 | 2篇 |
1908年 | 3篇 |
1904年 | 2篇 |
排序方式: 共有575条查询结果,搜索用时 15 毫秒
41.
42.
Organic compounds extracted from Michigan lakes and streams and added to algal cultures increase the growth rate of the green alga (Chlamydomonas reinhardi) when iron is present. Two-dimensional paper chromatography has shown that the iron is complexed by organic fractions containing an amine group. When isolated from natural waters containing a concentration of over 0.3 part per million alkyl benzene sulfonate, these compounds do not show an iron-binding capacity. Separation of this sulfonate from the amine complexes restores the iron-binding capability. These findings suggest that detergents may influence the mobility of iron by reducing the number of binding sites, and in this way may have an important secondary effect upon the primary production of lakes and streams. 相似文献
43.
44.
Changelian PS Flanagan ME Ball DJ Kent CR Magnuson KS Martin WH Rizzuti BJ Sawyer PS Perry BD Brissette WH McCurdy SP Kudlacz EM Conklyn MJ Elliott EA Koslov ER Fisher MB Strelevitz TJ Yoon K Whipple DA Sun J Munchhof MJ Doty JL Casavant JM Blumenkopf TA Hines M Brown MF Lillie BM Subramanyam C Shang-Poa C Milici AJ Beckius GE Moyer JD Su C Woodworth TG Gaweco AS Beals CR Littman BH Fisher DA Smith JF Zagouras P Magna HA Saltarelli MJ Johnson KS Nelms LF Des Etages SG Hayes LS Kawabata TT 《Science (New York, N.Y.)》2003,302(5646):875-878
Because of its requirement for signaling by multiple cytokines, Janus kinase 3 (JAK3) is an excellent target for clinical immunosuppression. We report the development of a specific, orally active inhibitor of JAK3, CP-690,550, that significantly prolonged survival in a murine model of heart transplantation and in cynomolgus monkeys receiving kidney transplants. CP-690,550 treatment was not associated with hypertension, hyperlipidemia, or lymphoproliferative disease. On the basis of these preclinical results, we believe JAK3 blockade by CP-690,550 has potential for therapeutically desirable immunosuppression in human organ transplantation and in other clinical settings. 相似文献
45.
46.
Kent JF 《Science (New York, N.Y.)》1947,105(2725):316-317
47.
Treusch S Hamamichi S Goodman JL Matlack KE Chung CY Baru V Shulman JM Parrado A Bevis BJ Valastyan JS Han H Lindhagen-Persson M Reiman EM Evans DA Bennett DA Olofsson A DeJager PL Tanzi RE Caldwell KA Caldwell GA Lindquist S 《Science (New York, N.Y.)》2011,334(6060):1241-1245
Aβ (beta-amyloid peptide) is an important contributor to Alzheimer's disease (AD). We modeled Aβ toxicity in yeast by directing the peptide to the secretory pathway. A genome-wide screen for toxicity modifiers identified the yeast homolog of phosphatidylinositol binding clathrin assembly protein (PICALM) and other endocytic factors connected to AD whose relationship to Aβ was previously unknown. The factors identified in yeast modified Aβ toxicity in glutamatergic neurons of Caenorhabditis elegans and in primary rat cortical neurons. In yeast, Aβ impaired the endocytic trafficking of a plasma membrane receptor, which was ameliorated by endocytic pathway factors identified in the yeast screen. Thus, links between Aβ, endocytosis, and human AD risk factors can be ascertained with yeast as a model system. 相似文献
48.
Harrison TM Stanley BJ Sikarskie JG Bohart G Ames NK Tomlian J Marquardt M Marcum A Kiupel M Sledge D Agnew D 《Journal of zoo and wildlife medicine》2011,42(2):317-321
A 14-yr-old female eastern black rhinoceros (Diceros bicornis michaeli) presented with progressive suppurative osteomyelitis in her left hind lateral toe. beta-Hemolytic Streptococcus sp. was isolated. The animal was treated with multiple systemic antibiotics, and topical wound cleansing. Repeated debridements and nail trimmings were performed for 5 mo prior to electing amputation. The toe was surgically amputated under general anesthesia between the first and second phalanges. Analgesia was diffused into the wound topically via a catheter and elastomeric pump. The open amputation site was covered with adherent drapes and a negative-pressure wound therapy device provided vacuum-assisted closure (V.A.C.) for 72 hr. Three months later this animal developed a deep dermal ulcer on the lateral aspect of the right hind limb, at the level of the stifle. Methicillin-resistant Staphylococcus aureus was isolated. The wound was managed by initial daily lavage, followed by 1 mo of V.A.C. therapy, with 72 hr between dressing changes. Clinically, this therapy expedited the formation of healthy granulation tissue and overall healing was accelerated. The animal tolerated the machine and bandage changes well via operant conditioning. The use of negative-pressure wound therapy appeared to shorten time to resolution of slow-healing wounds in black rhinoceros. 相似文献
49.
T E Knight M Kent J E Junk 《Journal of the American Veterinary Medical Association》2001,218(12):1946-8, 1936
Two cats from a single household were examined because of neurologic abnormalities suggestive of central vestibular disease. The owner had been renovating her 150-year-old house for the preceding 3 months, and renovations included chipping and sanding of old paint from windowsills and stair railings. Lead toxicosis was diagnosed on the basis of history and concentrations of lead in blood and urine. Both cats were treated with succimer. Treatment was not associated with any adverse effects, and both cats recovered completely. Ingestion of old paint from house renovations is the most common source of lead exposure in cats. Owners of cats with gastrointestinal tract or neurologic abnormalities should be questioned specifically about house renovations. 相似文献
50.
Gail I. Anderson BVSc MSc PhD Diplomate ACVS Kent Orlando BSc DDS James P. Waddell MD FRCS 《Veterinary surgery : VS》2001,30(4):311-318
OBJECTIVE: To establish whether hydroxyapatite (HA) coatings applied to metal total-hip-replacement components increased synovitis in the coxofemoral joint of dogs. Study Design-An in vivo research trial and histologic study. ANIMALS: Twenty-three large, mixed-breed dogs. METHODS: Arthroplasty components were implanted with HA on neither stem nor cup, or with HA applied to either the femoral component or with both stem and cup having HA applied in 23 dogs. Synovial inflammation was scored 3, 6, and 12 months after surgery. Synovial membrane thickness; polyethylene particulate load; fibrin exudate; membrane edema; mitotic index; giant-cell, mononuclear histiocyte, lymphocyte, and polymorph number; and collagen degeneration were scored and statistical analyses performed. RESULTS: Operated-side synovial thickness was greatly increased relative to control. Fibrin deposition, intramembranous edema, and collagen degeneration were similar within each time interval among the various component groups. The majority of inflammatory scores among the groups were unchanged. In this 12-month study, the presence of HA coatings appear not to have a marked impact on the development of synovial inflammation. CONCLUSIONS: HA-coated components do appear to contribute somewhat to the inflammatory load within the periprosthetic environment, but this effect is not marked. CLINICAL RELEVANCE: The major advantage of HA addition to arthroplasty components is enhanced osteoconductivity around metallic surfaces. The slight increase in particulate load seen in the presence of HA coatings may contribute to the development of aseptic loosening of arthroplasty components, but is unlikely to be the major causative factor. 相似文献