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11.
The objective of this study was to quantify the effect of inbreeding on carcass quality, growth rate, live conformation measures, and calving performance in purebred populations of Charolais, Limousin, Simmental, Hereford, and Angus beef cattle using data from Irish commercial and pedigree herds. Variables analyzed are reflective of commercial farming practices. Inbreeding was included in a linear mixed model as either a class variable or a linear continuous variable. Nonlinear effects were nonsignificant across all traits. Inbred animals had decreased carcass weight and less carcass fat. The effects of inbreeding were more pronounced in the British beef breeds. Effects for carcass weight ranged from -0.87 kg (Charolais) to -1.90 kg (Hereford) per 1% increase in inbreeding. Inbred Charolais and Hereford animals were younger at slaughter by 3 and 5 d, respectively, per percentage of increase in inbreeding, whereas the effect of inbreeding on age at slaughter differed significantly with animal sex in the Limousin and Angus breeds. Inbred Limousin and Angus heifers were younger at slaughter by 5 and 7 d, respectively, per percentage of increase in inbreeding. Continental animals were more affected by inbreeding for live muscling and skeletal conformational measurements than the British breeds; inbred animals were smaller and narrower with poorer developed muscle. Calf inbreeding significantly affected perinatal mortality in Charolais, Simmental, and Hereford animals. The effects were dependent upon dam parity and calf sex; however, where significant, the association was always unfavorable. Dam inbreeding significantly affected perinatal mortality in Limousin and Hereford animals. Effects differed by parity in Limousins. Inbred first-parity Angus dams had a greater incidence of dystocia. Although the effects of inbreeding were some-times significant, they were small and are unlikely to make a large financial effect on commercial beef production in Ireland. 相似文献
12.
Neurokinin receptors in recurrent airway obstruction: A comparative study of affected and unaffected horses
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Changaram S. Venugopal Earnestine P. Holmes Sumanth Polikepahad Susan Laborde Michael Kearney Rustin M. Moore 《Canadian journal of veterinary research》2009,73(1):25-33
The purpose of the study was to compare in vitro airway responses to neurokinin A & B (NKA and NKB) and expression of NK-2 receptors in airways of horses affected and unaffected with recurrent airway obstruction (RAO). Neurokinin-A, an inflammatory mediator belonging to the tachykinin family of neuropeptides, causes bronchoconstriction by binding to NK-2 receptors. Neurokinin-B is a lesser-known neuropeptide that acts on NK-3 receptors. Horses were placed into RAO-affected and RAO-unaffected groups based on their history, clinical scoring, and pulmonary function testing. Lung tissue from each lobe was collected for immunohistochemical staining for NK-2 receptors. Cumulative concentration-response relationships were determined on bronchial rings (4-mm wide) collected and prepared from the right diaphragmatic lung lobe to graded concentrations (half log molar concentrations 10−7M to 10−4M) of NKA and NKB. The results showed that NKA caused significantly greater contraction than NKB in both groups. In RAO-affected horses, both agents produced significantly greater bronchial contractions than those in the RAO-unaffected horses. Immunohistochemical staining showed that the overall NK-2 receptor distribution was significantly increased in bronchial epithelium and smooth muscles of bronchi and pulmonary vessels of RAO-affected than RAO-unaffected horses. The findings indicate that NK-2 receptors are up-regulated in RAO, suggesting that NK-2 receptor antagonists may have some therapeutic value in controlling the progression of airway hyperreactivity in horses affected with RAO. 相似文献
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14.
Control of gastrointestinal nematodes (GIN) in small ruminants in regions of the world where anthelmintic resistance is prevalent must rely on more than just chemical deworming strategies. The objective of this experiment was to compare two integrated treatment protocols for control of GIN (primarily Haemonchus contortus in this region) using anthelmintics, copper oxide wire particles (COWP) and FAMACHA(?), compared to traditional anthelmintic use only. Three separate trials were conducted on mature ewes, weaned goats, and weaned lambs in which three deworming management strategies were applied: 1) all animals were dewormed with levamisole at four week intervals (LEV), 2) individual animals were dewormed with moxidectin when scored≥4 (ewes) or ≥3 (kids and lambs) using FAMACHA(?) (FAM/MOX), 3) all animals were dewormed with moxidectin initially and again with COWP (2g) when group mean FEC exceeded 500 (ewes), 3000 (kids), or 1000 (lambs) eggs/g (MOX/COWP). In this final group, during periods between group treatments, individual animals were dewormed with albendazole and levamisole according to FAMACHA(?) score. Fecal egg counts (FEC) and blood packed cell volume (PCV) were determined every 7 days and body weight every 28 days for 30, 20, or 16 weeks in ewes, goats, and lambs, respectively. Efficacy of levamisole was 83.4-86.4%, efficacy of moxidectin was 93.5-100%, and efficacy of COWP was 10.8-98.1% among the three trials. The mean number of deworming treatments per animal that occurred for the LEV, FAM/MOX, and MOX/COWP groups, respectively, was 7.9, 0.6, and 2.5±0.4 (P<0.001) for ewes, 5.2, 1.6, and 3.4±0.3 (P<0.001) for goats, and 4.0, 1.7, and 3.6±0.2 (P<0.001) for lambs. Production (body weight of lambs weaned from ewes or final body weight of kids and lambs) was similar among management strategy groups for ewes and kids, but FAM/MOX lambs were lighter by the end of the trial (P<0.003). While more time and labor was required to use the FAMACHA(?) system, a more conservative use of anthelmintics occurred in the FAM/MOX group. 相似文献
15.
F.R. McKenzie J.L. Jacobs P. Riffkin G. Kearney 《African Journal of Range and Forage Science》2013,30(1-2):1-6
Abstract Effects of nitrogen (N) (0, 15, 30, 45 and 60 kg N ha?1) applied at five different times during autumn and early winter on the N fixation of Trifolium repens L. (white clover) in Lolium perenne L. (perennial ryegrass) / white clover pastures were examined (Experiment 1). Effects of applying different N fertilisers (e.g. urea and ammonium nitrate) at 45 kg N ha?1 in autumn, with and without phosphorus (P), potassium (K) and sulphur (S) on N fixation were also tested (Experiment 2). In Experiment 1, percentage N derived from the atmosphere (percent Ndfa) by white clover varied between 87% and 91% in the period after (24 to 36 days) N application. Increasing rates of N and time of application did not influence percent Ndfa. The amount of N fixed by white clover ranged from 0.8 to 3.7 kg N ha?1 in the period after N application. Increasing rates of applied N produced a significant (P<0.05) linear increase in the amount of N fixed. In Experiment 2, percent Ndfa and amount of N fixed (1.9 to 4.1 kg N ha?1) were unaffected by different N fertilisers, with and without P, K and S, in the period after (37 days) fertiliser application. For both experiments, fertiliser N increased dry matter yield while having no effect on white clover composition. It is concluded that single applications of N during the autumn and early winter benefit pasture growth without adversely affecting white clover N fixation or clover composition. This finding, however, will require further investigation. 相似文献
16.
George M. Strain MS PhD Michael T. Kearney MS Ivan J. Gignac Donald C. Levesque DVM Holly J. Nelson DVM Bruce L. Tedford MA Laura G. Remsen MS DVM 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1992,6(3):175-182
To screen for congenital deafness, brainstem auditory-evoked potential (BAEP) testing was performed on 1031 Dalmatians from three geographically separated areas. Phenotypic marker assessment was done to determine markers possibly associated with deafness. Markers included sex, hair coat color, pigmentation of different areas of skin (eye rims, nose, and ears), presence of a patch, spot size and marking (density of spotting), sire and dam BAEP status, and presence of iris and retinal tapetal pigmentation. Combined data from all test sites showed 8.1% bilateral deafness (N = 83 dogs) and 21.6% unilateral deafness (N = 223), or an overall 29.7% incidence of hearing disorders. Significant (P less than 0.05) associations with deafness for the data from all test sites combined were seen for patch, sire and dam BAEP, iris pigment, and retinal pigment. However, results differed for several of the significant phenotypic markers when analyses were done on the data from the individual test sites; changes from significant to not significant were found. This suggested the existence of multiple populations of deafness patterns, and reinforced the precautionary conclusion that associations of phenotypic markers with deafness are not necessarily functionally significant. 相似文献
17.
Effects of pH, temperature, and salinity on persistence of avian influenza viruses in water 总被引:5,自引:0,他引:5
The combined effects of water temperature, salinity, and pH on persistence of avian influenza virus (AIV) were evaluated in a model distilled-water system using three isolates from ducks sampled in Cameron Parish, Louisiana. Variables were tested within the ranges normally associated with surface water. Differences were detected between temperature (17 C and 28 C), pH (6.2, 7.2, 8.2), and salinity (0 ppt and 20 ppt), with a strong interactive effect observed between pH and salinity. Estimated persistence of infectivity for 1 x 10(6) mean tissue-culture infective dose of A/mottled duck/LA/38M/87 (H6N2) was longest at 17 C/0 ppt/pH 8.2 (100 days) and shortest at 28 C/20 ppt/pH 8.2 (9 days). Differences in the response to these variables were apparent between viruses. The ability of AIV to persist in surface water was also evaluated using samples collected from varied waterfowl habitats in coastal Louisiana. Observations were consistent with the model system, with duration of infectivity decreasing with increased salinity and pH. This suggests that experimental results may have application to field conditions. 相似文献
18.
During the spring of 1985, 40 calves grazed pastures known to have high numbers of spring inhibition-prone, infective Ostertagia ostertagi larvae. Calves were removed from pasture and placed in outdoor pens with concrete floors from 10 days prior to treatment until necropsy 14 days after treatment. Ten calves were allocated to each of 4 treatment groups, and oxfendazole was administered to each group by intraruminal injection at dosages of 0, 2.25, 4.5, and 6.75 mg/kg of body weight. Efficacies greater than or equal to 94.6% were achieved at dosages of 4.5 and 6.75 mg/kg against adult Ostertagia spp, Trichostrongylus spp, Haemonchus placei, Cooperia punctata, Bunostomum phlebotomum, Oesophagostomum radiatum, and Dictyocaulus viviparus. Efficacy against inhibited larvae of O ostertagi was variable, with the highest efficacy (90.2%) attained at a dosage of 6.75 mg/kg. 相似文献
19.
Cloacal and tracheal swabs were collected from 1389 hunter-killed ducks in Cameron Parish, Louisiana, during the 1986 and 1987 waterfowl seasons. Twenty-eight avian influenza viruses (AIVs) were isolated from 605 blue-winged teal (Anas discors), 75 mottled ducks (A. fulvigula), 375 gadwalls (A. stepera) and 334 green-winged teal (A. crecca). Prevalence estimates of AIV in ducks sampled during September, November, and December through January were 3.1%, 2.0%, and 0.4%, respectively. Differences in prevalence were detected by season (P = 0.044) and age class (P = 0.036). Two isolations from resident mottled ducks document transmission of AIV on these wintering areas. Much subtype diversity was present, with nine of 13 hemagglutinin (HA) and nine of nine neuraminidase (NA) subtypes recovered. Predominant HA and NA subtypes were typical of AIVs commonly associated with waterfowl. Results indicate that AIVs are transmitted in the wintering areas, and, although prevalence is low, these viruses continue to circulate within these duck populations during winter. 相似文献
20.