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排序方式: 共有244条查询结果,搜索用时 15 毫秒
161.
Tomohito ISHIZUKA Jun TAMURA Tsukasa NAGARO Kanako SUDO Takaharu ITAMI Mohammed Ahamed UMAR Kenjirou MIYOSHI Tadashi SANO Kazuto YAMASHITA 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2014,76(12):1577-1582
Effects of intermittent
positive pressure ventilation (IPPV) on cardiopulmonary function were evaluated in horses
anesthetized with total intravenous anesthesia using constant rate infusions of
medetomidine (3.5 µg/kg/hr), lidocaine (3 mg/kg/hr), butorphanol (24
µg/kg/hr) and propofol (0.1 mg/kg/min) (MLBP-TIVA). Five horses were
anesthetized twice using MLBP-TIVA with or without IPPV at 4-week interval (crossover
study). In each occasion, the horses breathed 100% oxygen with spontaneous ventilation
(SB-group, n=5) or with IPPV (CV-group, n=5), and changes in cardiopulmonary parameters
were observed for 120 min. In the SB-group, cardiovascular parameters were maintained
within acceptable ranges (heart rate: 33–35 beats/min, cardiac output: 27–30
l/min, mean arterial blood pressure [MABP]: 114–123 mmHg, mean
pulmonary arterial pressure [MPAP]: 28–29 mmHg and mean right atrial pressure [MRAP]:
19–21 mmHg), but severe hypercapnea and insufficient oxygenation were observed (arterial
CO2 pressure [PaCO2]: 84–103 mmHg and arterial O2
pressure [PaO2]: 155–172 mmHg). In the CV-group, normocapnea (PaCO2:
42–50 mmHg) and good oxygenation (PaO2: 395–419 mmHg) were achieved by the IPPV
without apparent cardiovascular depression (heart rate: 29–31 beats/min, cardiac output:
17–21 l /min, MABP: 111–123 mmHg, MPAP: 27–30 mmHg and MRAP: 15–16 mmHg).
MLBP-TIVA preserved cardiovascular function even in horses artificially ventilated. 相似文献
162.
163.
H Kitagawa Y Sasaki K Ishihara Y Hirano 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1990,52(6):1211-1217
To investigate whether adult heartworms harboring in the pulmonary arteries contribute to pulmonary hypertension, we determined the cardio-pulmonary values immediately before and after removal of heartworms from the pulmonary arteries and before and after insertion of live worms in their place. In 10 heartworm-infected dogs, 8 to 46 worms were removed. The mean pulmonary arterial pressure fell significantly from 24.5 +/- 7.9 mmHg to 16.3 +/- 4.9 mmHg (p less than 0.01) immediately after removal. The right cardiac output decreased in 7 of the 10 cases. The total pulmonary resistance and right ventricular stroke work index also decreased. At 24 hours after removal, live heartworms were put back into the pulmonary arteries of their host dog. The mean pulmonary arterial pressure elevated significantly (p less than 0.01) immediately after insertion. The right cardiac output further decreased in 7 of the 10 dogs, and the total pulmonary resistance and right ventricular stroke work index increased. Separate from this, 12 to 42 heartworms were transplanted into the pulmonary arteries of 5 heartworm-free dogs. Immediately after transplantation, the pulmonary arterial pressure did not show any significant change. However, the stroke volume decreased, and the total pulmonary resistance increased. These facts suggest a contribution of live heartworms to the pulmonary hypertension, although there is a complicated interaction among the presence of heartworms, the pulmonary lesions and the pulmonary hypertension. 相似文献
164.
Fecal samples were collected from 325 adult cattle and 108 pigs in a slaughterhouse in Hokkaido, the northern island of Japan. Five adult cattle were found to be positive for oocysts of Cryptopsoridium (1.5%). The oocysts were morphologically similar to those of Cryptosporidium andersoni. The partial sequence of the 18S rRNA gene of the isolate was 100% identical with that of the C. andersoni Kawatabi strain. SCID mice were infected after oral administration. Based on the morphology of the oocysts, the sequence of the 18S rRNA gene and the infectivity to SCID mice, the isolate was concluded to be of the same type as the C. andersoni Kawatabi strain that has been isolated in Honshu, the main island of Japan. 相似文献
165.
Harada K Asai T Kojima A Oda C Ishihara K Takahashi T 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2005,67(10):999-1003
We examined the 12 antimicrobial susceptibilities of 175 E. coli isolates from sick cattle and pigs by an agar dilution method. Resistance was found in 78.3% of isolates for oxytetracycline, 70.3% of isolates for dihydrostreptomycin, and 49.1% of isolates for ampicillin. When compared with healthy animals reported by Kijima-Tanaka et al., resistance rates for 11 antimicrobial agents were higher in sick cattle than in healthy cattle, and resistance rates for all antimicrobial agents were higher in sick pigs than in healthy pigs. Comparing cattle and pigs, resistance rates to colistin was higher in porcine isolates than in bovine isolates, but was lower in porcine isolates than in bovine isolates for cefazolin. With regard to the association of virulence factors, higher resistance rates to colistin and enrofloxacin were observed in STEC (61 strains) than in non-STEC (57 strains) among porcine isolates, while there were no significant differences in bovine isolates. In conclusion, these results can be considered helpful for adequate selection and prudent use of antimicrobial agents for several types of colibacillosis. 相似文献
166.
167.
168.
Much theoretical work has been devoted to understanding the role of strong electron correlations in high-temperature superconductivity mainly through magnetic interactions, but the possible role of electron correlation in ferroelectricity of metal oxides has not received attention. Diagonalization of a simple many-body, tight-binding Hamiltonian shows that the electron-lattice interaction is dramatically enhanced in some cases by strong electron correlation because of deformation-induced charge transfer. This effect may be closely related to ferroelectricity and superconductivity in transition metal oxides. 相似文献
169.
Bolt DM Ishihara A Weisbrode SE Bertone AL 《American journal of veterinary research》2008,69(7):861-867
OBJECTIVE: To evaluate the effects of triamcinolone acetonide (TA), sodium hyaluronate (HA), amikacin sulfate (AS), and mepivacaine hydrochloride (MC) on articular cartilage morphology and matrix composition in lipopolysaccharide (LPS)-challenged and unchallenged equine articular cartilage explants. Sample POPULATION: 96 articular cartilage explants from 4 femoropatellar joints of 2 adult horses. PROCEDURES: Articular cartilage explants were challenged with LPS (100 ng/mL) or unchallenged for 48 hours, then treated with TA, HA, AS, and MC alone or in combination for 96 hours or left untreated. Cartilage extracts were analyzed for glycosaminoglycan (GAG) content by dimethyl-methylene blue assay (ng/mg of dry wt). Histomorphometric quantification of total lacunae, empty lacunae, and lacunae with pyknotic nuclei was recorded for superficial, middle, and deep cartilage zones. RESULTS: LPS induced a significant increase in pyknotic nuclei and empty lacunae. Treatment with TA or HA significantly decreased empty lacunae (TA and HA), compared with groups without TA or HA, and significantly decreased empty lacunae of LPS-challenged explants, compared with untreated explants. Treatment with AS or MC significantly increased empty lacunae in unchallenged explants, and these effects were attenuated by TA. Treatment with MC significantly increased empty lacunae and pyknotic nuclei and, in combination with LPS, could not be attenuated by TA. Content of GAG did not differ between unchallenged and LPS-challenged explants or among treatments. CONCLUSIONS AND CLINICAL RELEVANCE: Treatment with TA or HA supported chondrocyte morphology in culture and protected chondrocytes from toxic effects exerted by LPS, AS, and MC. 相似文献
170.