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71.
Conjugated polymers and indium arsenide-based nanocrystals were used to create near-infrared plastic light-emitting diodes. Emission was tunable from 1 to 1.3 micrometers--a range that effectively covers the short-wavelength telecommunications band--by means of the quantum confinement effects in the nanocrystals. The external efficiency value (photons out divided by electrons in) is approximately 0.5% (that is, >1% internal) and is mainly limited by device architecture. The near-infrared emission did not overlap the charge-induced absorption bands of the polymer. 相似文献
72.
A common onc gene sequence transduced by avian carcinoma virus MH2 and by murine sarcoma virus 3611 总被引:17,自引:0,他引:17
N C Kan C S Flordellis G E Mark P H Duesberg T S Papas 《Science (New York, N.Y.)》1984,223(4638):813-816
A common cellular sequence was independently transduced by avian carcinoma virus MH2 (v-mht) and murine sarcoma virus (MSV) 3611 (v-raf). Comparison of the nucleotide sequences of v-mht and v-raf revealed a region of homology that extends over 969 nucleotides. The homology between the corresponding amino acids was about 95 percent with only 19 of 323 amino acids being different. With this example, 5 of the 19 known different viral onc genes have been observed in viruses of different taxonomic groups. These data indicate that (i) the number of cellular proto-onc genes is limited because, like other viruses of different taxonomic groups, MH2 and MSV 3611 have transduced the same onc gene-specific sequences from different cell species and (ii) that specific deletion and linkage of the same proto-onc sequences to different viral vector elements affect the oncogenic potential of the resulting viruses. The difference in transformation capabilities of MH2 and MSV 3611 serves as an example. 相似文献
73.
Identification of HTLV-III/LAV sor gene product and detection of antibodies in human sera 总被引:24,自引:0,他引:24
N C Kan G Franchini F Wong-Staal G C DuBois W G Robey J A Lautenberger T S Papas 《Science (New York, N.Y.)》1986,231(4745):1553-1555
The nucleotide sequence of the genome of HTLV-III, the infectious agent etiologically associated with the acquired immune deficiency syndrome, predicts a small open reading frame, termed sor, located between the pol and env genes. A DNA segment containing 82 percent of the sor region was inserted into a prokaryotic expression vector, pJL6, to determine whether sor encodes a viral protein and to gain some insight into its possible function. The bacterially synthesized sor protein reacted with sera from individuals infected with HTLV-III, indicating that sor is expressed as a protein product or products that are immunogenic in vivo. Antibodies to the purified, bacterially synthesized sor protein were found to react specifically with the same protein and also with a protein of molecular weight 23,000 (23K) in HTLV-III-infected H9 cell extracts. The 23K protein comigrated with a protein immunoprecipitated by the serum of a hemophiliac patient with antibodies to HTLV-III, suggesting that this protein is probably the sor gene product. 相似文献
74.
Black widow spider venom selectively poisons motor nerve endings. A progressive and irreversible failure of neuromuscular transmission occurs in the cat. Electron microscopy of the poisoned nerve-muscle junction shows a sequence of motor nerve ending damage that culminates in disruption of the prejunctional membrane and loss of all organelles, including synaptic vesicles. The postjunctional membrane was morphologically unaffected. After complete poisoning, the contractile response to exogenous acetylcholine was severely impaired, an indication that the prejunctional site is chiefly involved in the contractile response produced by exogenous acetylcholine and that the pre- and postjunctional effects of acetylcholine were separated. 相似文献
75.
Asagiri M Hirai T Kunigami T Kamano S Gober HJ Okamoto K Nishikawa K Latz E Golenbock DT Aoki K Ohya K Imai Y Morishita Y Miyazono K Kato S Saftig P Takayanagi H 《Science (New York, N.Y.)》2008,319(5863):624-627
Cathepsin K was originally identified as an osteoclast-specific lysosomal protease, the inhibitor of which has been considered might have therapeutic potential. We show that inhibition of cathepsin K could potently suppress autoimmune inflammation of the joints as well as osteoclastic bone resorption in autoimmune arthritis. Furthermore, cathepsin K-/- mice were resistant to experimental autoimmune encephalomyelitis. Pharmacological inhibition or targeted disruption of cathepsin K resulted in defective Toll-like receptor 9 signaling in dendritic cells in response to unmethylated CpG DNA, which in turn led to attenuated induction of T helper 17 cells, without affecting the antigen-presenting ability of dendritic cells. These results suggest that cathepsin K plays an important role in the immune system and may serve as a valid therapeutic target in autoimmune diseases. 相似文献
76.
辜堪生 《河南科技大学学报(农学版)》2001,21(1):45-47,60
分析了经济转型时期国企职工的主人翁地位失落的原因,提出了国有企业保障企业职工主人翁地位的措施:充分保证和利用职代会来实现企业的民主管理,很好地利用工会这一企业职工的群众性组织。 相似文献
77.
化归方法是数学解题中的一个重要方法。本文从思维方法的角度论述了化归方法的基本含义,探讨化归方法在数学解题中的应用。 相似文献
78.
79.
从植物营养的观点出发,转化土壤中不溶性有机磷和无机磷化合物为可溶性磷酸盐的过程具有极重大的意义,结果可以大大地提高土壤的生产力。最近,P.A.曼吉娜(Р.А.Менкина)指出:Bacillus megatherium var .phos-phaticum 与 Serratia var.phosphaticum 能矿化卵磷脂或核酸一类的有机磷化合 相似文献
80.
The study here was conducted on nearly 12,000 apricot seedlings in the Malatya Region in the Eastern part of Turkey. This
region is famous for its horticulture based mainly on apricot production and the Country's highest apricot production originates
from this region. The flower and fruit characteristics of all populations, which include apricot seedlings, in the region
were evaluated. Based on their horticultural performances, 13 genotypes were selected, of which seven were considered as apricots
served in dried form and six as in table consumption form. Among the selected genotypes, the fruit weight ranged between 28.5
and 71.19 g, soluble solids ranged between 12.7 and 26.5%, while the range in total acidity was between 0.35 and 1.80% and
fruit development period was between 87 and 183 days. To determine the selected genotypes performance in a similar environment,
they were grafted on to 4-year-old rootstocks. The results from these combinations showed that there was some decrease, especially
in fruit size and soluble solids, in the genotypes performance when compared to the results of the initial observations. Some
differences were also detected in taste, fruit shape, pit shape, fruit flesh firmness, skin and flesh colors. The dry fruit
yield was determined as 22.50–28.36% for the selected dry apricot genotypes. The dry fruit yield of all seven genotypes considered
for dry consumption were similar to ‘Hacıhaliloğlu’ and higher than ‘Canino’, which were evaluated as control cultivars. 相似文献