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61.
62.
Garzione CN Hoke GD Libarkin JC Withers S MacFadden B Eiler J Ghosh P Mulch A 《Science (New York, N.Y.)》2008,320(5881):1304-1307
The surface uplift of mountain belts is generally assumed to reflect progressive shortening and crustal thickening, leading to their gradual rise. Recent studies of the Andes indicate that their elevation remained relatively stable for long periods (tens of millions of years), separated by rapid (1 to 4 million years) changes of 1.5 kilometers or more. Periodic punctuated surface uplift of mountain belts probably reflects the rapid removal of unstable, dense lower lithosphere after long-term thickening of the crust and lithospheric mantle. 相似文献
63.
Meehl GA Washington WM Collins WD Arblaster JM Hu A Buja LE Strand WG Teng H 《Science (New York, N.Y.)》2005,307(5716):1769-1772
Two global coupled climate models show that even if the concentrations of greenhouse gases in the atmosphere had been stabilized in the year 2000, we are already committed to further global warming of about another half degree and an additional 320% sea level rise caused by thermal expansion by the end of the 21st century. Projected weakening of the meridional overturning circulation in the North Atlantic Ocean does not lead to a net cooling in Europe. At any given point in time, even if concentrations are stabilized, there is a commitment to future climate changes that will be greater than those we have already observed. 相似文献
64.
To rigorously test the in vivo cell fate specificity of bone marrow (BM) hematopoietic stem cells (HSCs), we generated chimeric animals by transplantation of a single green fluorescent protein (GFP)-marked HSC into lethally irradiated nontransgenic recipients. Single HSCs robustly reconstituted peripheral blood leukocytes in these animals, but did not contribute appreciably to nonhematopoietic tissues, including brain, kidney, gut, liver, and muscle. Similarly, in GFP+:GFP- parabiotic mice, we found substantial chimerism of hematopoietic but not nonhematopoietic cells. These data indicate that "transdifferentiation" of circulating HSCs and/or their progeny is an extremely rare event, if it occurs at all. 相似文献
65.
Bartke A Wright JC Mattison JA Ingram DK Miller RA Roth GS 《Science (New York, N.Y.)》2002,296(5576):2141-2; author reply 2141-2
66.
Treusch S Hamamichi S Goodman JL Matlack KE Chung CY Baru V Shulman JM Parrado A Bevis BJ Valastyan JS Han H Lindhagen-Persson M Reiman EM Evans DA Bennett DA Olofsson A DeJager PL Tanzi RE Caldwell KA Caldwell GA Lindquist S 《Science (New York, N.Y.)》2011,334(6060):1241-1245
Aβ (beta-amyloid peptide) is an important contributor to Alzheimer's disease (AD). We modeled Aβ toxicity in yeast by directing the peptide to the secretory pathway. A genome-wide screen for toxicity modifiers identified the yeast homolog of phosphatidylinositol binding clathrin assembly protein (PICALM) and other endocytic factors connected to AD whose relationship to Aβ was previously unknown. The factors identified in yeast modified Aβ toxicity in glutamatergic neurons of Caenorhabditis elegans and in primary rat cortical neurons. In yeast, Aβ impaired the endocytic trafficking of a plasma membrane receptor, which was ameliorated by endocytic pathway factors identified in the yeast screen. Thus, links between Aβ, endocytosis, and human AD risk factors can be ascertained with yeast as a model system. 相似文献
67.
Natalia Kirichenko Julie Flament Yuri Baranchikov Jean-Claude Grégoire 《European Journal of Forest Research》2011,130(6):1067-1074
The Siberian moth, Dendrolimus sibiricus, Tschtv. is the most harmful defoliator of coniferous forests in North Asia. The pest has already spread over the Urals and
continues moving westwards. Recently, it has been recommended for quarantine in member countries by European and Mediterranean
Plant Protection Organization (EPPO). The performances of the pest on coniferous species planted in Europe were assessed on
a range of potted trees corresponding to the spectrum of economically important conifers in the EU: European larch Larix decidua, Norway spruce Picea abies, Scots pine Pinus sylvestris, European black pine Pinus nigra, and the North American species: Douglas fir Pseudotsuga menziesii and grand fir Abies grandis. Larvae showed a potential to survive and complete the development on all these host tree species. Favorable hosts were grand
fir, European larch, and Douglas fir that allowed higher survival, better larval development, and as a result, yielded heavier
pupae and adult moths with higher longevity. Black pine was a poor host but, however, could still support larval and pupal
development. Norway spruce and Scots pine had an intermediate behavior. If accidentally introduced to Europe, the Siberian
moth may become especially damaging in forest stands predominated by European larch and by the North American firs. Norway
spruce and especially the two-needle pines will be less prone to intensive defoliation by this species. The fact that the
pest may damage the range of economically important coniferous species should be taken into account in the pest risk assessment
for Europe and also for North America where the Siberian moth occurrence is considered likely. 相似文献
68.
69.
Human development of freshwater ecosystems has lead to drastic changes in freshwater fish faunas, including the loss of many native species and the gain of non-natives. Typically conservation ecologists view these two opposing forces as contributing to biological homogenization, and consider homogenization as one of the principle negative consequences of urbanization. However, homogenization is only one outcome out of many that can result from the loss and gain of species. In particular, it is possible for invasions and extinctions to lead to differentiation; a process whereby two (or more) regions become less similar to one another through time. Using the freshwater fishes of California, we show that urbanization is highly positively correlated to both the endangerment of native fish and the invasion of non-native fish within watersheds. Despite this, the fish faunas of California’s watersheds have differentiated from one another through time. Furthermore, the degree of differentiation is positively correlated with measures of urbanization, which is contrary to expectation. We suggest that this result reflects: (1) the haphazard manner in which non-native fishes have been introduced into California watersheds, (2) the difficulty that both native and non-native fishes have in expanding their geographical ranges, and (3) the continued presence of vestiges of formerly distinct regional faunas. This pattern of differentiation among watersheds is likely a matter of scale, as previous work on freshwater fishes has demonstrated homogenization at both larger and smaller spatial scales. In addition the observed pattern is probably a short-term (temporal) phenomena and will disappear with continued invasion and extinction. We suggest that similar patterns may occur for other taxa that have limited natural dispersal abilities and that are idiosyncratically released as non-natives via human activities (e.g. herptiles). 相似文献
70.
Many threatened primates now exist in fragmented forest habitats. The survival of these populations may depend on their ability to utilise agricultural or other matrix habitats between forest fragments, but this is poorly known. Here, we systematically investigate an arboreal primate’s use of a heterogeneous matrix in a fragmented forest landscape: the Angola black-and-white colobus (Colobus angolensis palliatus) in southern Kenya. We used a novel technique, based on semi-structured interviews with local informants, to address the difficulty of sampling relatively rare but important events, such as dispersal between fragments. We found that colobus frequently travelled and foraged in indigenous matrix vegetation (such as mangrove, wooded shrubland and shrubland) up to 4 km from the nearest forest fragments. Agricultural habitats, such as perennial plantation (coconut, mango and cashew nut) were also used by colobus for travelling and foraging (in remnant indigenous trees). The probability of sighting colobus in the matrix increased with the proportion of both tall (>6 m) vegetation cover and food tree cover, but declined with distance from forest habitat. Our findings suggest that certain matrix habitats are important for C. a. palliatus, and that future primate conservation initiatives might benefit from adopting a ‘landscape-level’ approach to habitat management, particularly in fragmented forest systems. 相似文献