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991.
992.
Nagendra Kumar Kaushik Neha Kaushik Sunil Pardeshi Jai Gopal Sharma Seung Hyun Lee Eun Ha Choi 《Marine drugs》2015,13(11):6792-6817
The substance secreted by mussels, also known as nature’s glue, is a type of liquid protein that hardens rapidly into a solid water-resistant adhesive material. While in seawater or saline conditions, mussels can adhere to all types of surfaces, sustaining its bonds via mussel adhesive proteins (MAPs), a group of proteins containing 3,4-dihydroxyphenylalanine (DOPA) and catecholic amino acid. Several aspects of this adhesion process have inspired the development of various types of synthetic materials for biomedical applications. Further, there is an urgent need to utilize biologically inspired strategies to develop new biocompatible materials for medical applications. Consequently, many researchers have recently reported bio-inspired techniques and materials that show results similar to or better than those shown by MAPs for a range of medical applications. However, the susceptibility to oxidation of 3,4-dihydroxyphenylalanine poses major challenges with regard to the practical translation of mussel adhesion. In this review, various strategies are discussed to provide an option for DOPA/metal ion chelation and to compensate for the limitations imposed by facile 3,4-dihydroxyphenylalanine autoxidation. We discuss the anti-proliferative, anti-inflammatory, anti-microbial activity, and adhesive behaviors of mussel bio-products and mussel-inspired materials (MIMs) that make them attractive for synthetic adaptation. The development of biologically inspired adhesive interfaces, bioactive mussel products, MIMs, and arising areas of research leading to biomedical applications are considered in this review. 相似文献
993.
Heeson Chon Byungryul Choi Gajin Jeong Eungyo Lee Seunghui Lee 《Comparative immunology, microbiology and infectious diseases》2010,33(6):e41-e49
The objective of this study was to evaluate the immunomodulatory effects of specific bacterial metabolites of Lactobacillus plantarum 10hk2 to induce anti-inflammatory mediators in cell cultures of the murine macrophage cell line, RAW 264.7. The effects of the extracellular metabolites of this bacterial strain were examined by dividing them into protein and polysaccharide fractions. A specific protein fraction (8.7 kDa) was found to be a strong IL-10 inducer in LPS-stimulated RAW 264.7 cells and suppressed LPS-induced NF-κB induction and inhibited LPS-induced phosphorylation of I-κB and p38 MAPK. To the best of our knowledge, this was the first study that investigated the anti-inflammatory effects of an extracellular peptide derived from lactic acid bacteria. In addition, we characterized the inhibitory mode of this molecule in the induction of proinflammatory cytokines. Based on the findings presented in this study, this molecule holds promise for use as an agent to modulate inflammation related diseases. 相似文献
994.
Tree growth and the increase in inorganic nutrients during a growing season were studied in 3-year-old, container-grown ‘Fuyu’ persimmon trees with different levels of fruit-load. Fruit-load was varied by adjusting the leaf–fruit ratio to 10, 20, 30, and 60 on July 5. Some trees were completely defruited. The whole trees were harvested on November 5 of that year, and increases in dry weight and inorganic elements in different tree parts during the season were measured. A lower leaf–fruit ratio resulted in a higher yield but also decreased fruit weight, soluble solids, and fruit color. Dry weight of the aerial woods and root increased significantly with a greater ratio. However, total dry weight including the fruits was higher in the lower ratio trees than in the higher ratio trees; the weight of a tree that maintained the ratio of 10 was 35% higher than a tree without fruit. Fruits accounted for 62% of total dry weight when the ratio was 10 and 27% when the ratio was 60. The leaf–fruit ratio did not significantly alter the total increase in P, K, Ca, and Mg content. N tended to decrease with an increasing leaf–fruit ratio. Of the total increases of N, P, and K during the season, the fruits accounted for 30%, 50%, and 54% at the ratio of 20, respectively, and the percentages increased to 44, 81, and 74 at the ratio of 10. The inorganic element content in the aerial woods and root tended to increase with greater ratios, especially in the root. When trees were defruited, N and K increases in the root accounted for 44% and 35% of the total increase, respectively. These results indicated that persimmon orchard fertilization programs with different fruit-load levels should accommodate the proportion of nutrients partitioned to fruits that are removed permanently from the tree. 相似文献
995.
Yong Duck Kim Ji Yun Min Mi Jin Jeong Hyun Jin Song Jung Gyu Hwang Chandrakant S. Karigar Gang Won Cheong Myung Suk Choi 《Journal of Wood Science》2010,56(5):411-417
A rapid and efficient colorimetric method based on the use of Fast Blue B-salt (FBB) was established to select catechin-rich
tea trees (Camellia sinensis L.). The catechin levels measured by the colorimetric method under optimized reaction conditions correlated closely with
estimations by high-performance liquid chromatography (HPLC) analysis. The FBB colorimetric method was successfully used to
classify 160 tea trees on the basis of their catechin contents into rich and poor lines. HPLC analysis of the FBB-selected
tea tree extracts showed them to contain (−)-epigallocatechin 186 mg/g in tea tree line HR-29, (−)-epicatechin 43.7 mg/g in
HR-82, (−)-epigallocatechin gallate 4.32 mg/g in HR-29, and (−)-epicatechin gallate 0.22 mg/g in HR-52. Classification of
tea trees from the Hadong region into catechin-rich and -poor trees was independent of the growing season. Thus the FBB colorimetric
method could find application as a reliable tool in screening and selection of tea trees on the basis of their catechin content. 相似文献
996.
Lee H Kim M Choi M Lee N Chang J Yoon J Choi M 《Journal of Feline Medicine and Surgery》2010,12(12):936-941
Obesity is a common nutritional disorder in cats and it increases the risk factors for various diseases. The aim of this study is to suggest a method for the evaluation of feline obesity using computed tomography. The attenuation range from -156 to -106 was determined as the range of feline abdominal adipose tissue. With this range, total (TAT), visceral (VAT) and subcutaneous (SAT) adipose tissues were measured. The best correlation between the adipose tissue in cross-sectional image and entire abdomen volume was obtained at the L3 and L5 levels. The mean VAT/SAT ratio was 1.18±0.32, which was much higher than in humans. The cats with an overweight body condition had a significantly lower VAT/SAT ratio than cats with an ideal body condition. This technique may contribute to both the clinical diagnosis and the experimental study of feline obesity. 相似文献
997.
998.
The coloration of poly(lactic acid) (PLA) fiber with 18 carbocyclic monoazo disperse dyes bearing a hydrolyzable phthalimide
ring fused to the aromatic ring of their diazo components has been investigated. The phthalimidyl nitrogen atom was substituted
with either a n-butyl, sec-butyl, or isopropyl group, while the adjoining phenyl ring bore a substitution pattern typical of commercial colorants. There
was a broad correlation between percentage dye exhaustion onto PLA and that onto polyester (PET) fiber, although significant
differences in certain instances were apparent with no clear trends regarding dye structure. Attempts to explain the observed
percentage exhaustion values by mapping them to calculated partition coefficient or solubility parameter values were unsuccessful.
Wash fastness was relatively good compared to that of some conventional disperse dyes applied to PLA. As was found to be the
case with PET, the wash fastness of dyes on PLA tended to be highest when their diazo ring was substituted with electron acceptors. 相似文献
999.
1000.
Molecular epidemiology of Newcastle disease in Republic of Korea 总被引:4,自引:0,他引:4
Twenty-three strains of Newcastle disease virus (NDV) isolated between 1988 and 1999 in Republic of Korea were studied by partial nucleotide sequencing of fusion (F) gene and phylogenetic analysis. Most of Korean strains formed a distinctive cluster in genotype VI and they were genetically distant (4.0-8.7%) from other subtypes (a, b, c, d, and e), and termed provisionally VIf. Some Korean strains isolated in 1995 were grouped into genotype VIIa and they were closer to Taiwan strains than western Europe. The results suggest that the genotype VIf strains have been maintained by enzootic infections during the past decade, while genotype VIIa appears to be introduced more recently in Republic of Korea. 相似文献