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71.
Renal failure and hyperparathyroidism in an Alaskan Malamute pup 总被引:1,自引:0,他引:1
In a 5-month-old male Alaskan Malamute, clinicopathologic and radiographic findings supported a diagnosis of renal failure and hyperparathyroidism. At necropsy, the parathyroid glands were enlarged and the kidneys were shrunken and irregular. The histopathologic findings were consistent with the diagnosis of logic findings were consistent with the diagnosis of terminal renal failure and hyperparathyroidism. Based on the history, a heritable disorder was suspected. 相似文献
72.
R L Burk E F Meierhenry C W Schaubhut 《Journal of the American Veterinary Medical Association》1975,167(8):749-751
An 81/2-year-old female domestic short-haired cat was admitted with signs of chronic cystitis. Radiography revealed marked and irregular thickening of the bladder wall. Biopsy revealed the thickening to be a malignant tumor of muscle origin and treatment with proteolytic enzymes was instituted. After one month, the cat was euthanatized because of uremia associated with progressive tumor growth. At necropsy the bladder was grossly thickened. The histopathologic diagnosis was leiomyosarcoma. 相似文献
73.
74.
Gabrielska J Soczyńska-Kordala M Hładyszowski J Zyłka R Miśkiewicz J Przestalski S 《Journal of agricultural and food chemistry》2006,54(20):7735-7746
Our earlier studies have shown that the compounds diphenyltin dichloride (DPhT) and triphenyltin chloride (TPhT) in the presence of UVC radiation enhanced the degree of phosphatidylcholine liposome membrane oxidation (J. Agric. Food Chem. 2005, 53, 76-83). The prooxidative behavior of the compounds has now been confirmed with the electron paramagnetic resonance method, which proved the possibility that the studied compounds can exist in free radical forms. The present work investigates the possibility of the protective action of quercetin on phosphatidylcholine liposome membranes exposed to the prooxidative action of DPhT and TPhT induced by UV radiation (lambda = 253.7 nm). The concentrations of quercetin and its equimolar mixtures with DPhT and TPhT were determined (and compared with well-known antioxidants as standards-trolox and butylated hydroxytoluene, also in the presence of phenyltins) as those that induce 50% inhibition in oxidation of liposomes radiated with UV. They are 5.1 +/- 0.10, 2.9 +/- 0.12, and 1.9 +/- 0.08 microM (differences between the values are statistically significant), constituting the following sequence of antioxidative activity: quercetin:TPhT > quercetin:DPhT > quercetin. This relation is confirmed by the results on the antiradical ability of quercetin and its mixtures with DPhT and TPhT toward the free radical 1,1-diphenyl-2-pricrylhydrazil. Similar sequences obtained in both studies suggest a possible mechanism of the antiradical action of the mixtures as free radical scavengers. We suggested that (i) quercetin's ability, documented by spectrophotometric, infrared attenuated total reflectance spectroscopy, (1)H NMR, and molecular modeling methods, to form complexes with phenyltins indicates a possible way of protection against the peroxidation caused by the free radical forms of phenyltins and (ii) the differentiation in the action of the quercetin/TPhT and quercetin/DPhT associates (statisticaly significant) may result from a different localization in the liposome membrane, which is indicated by the results of the fluorimetric studies. 相似文献
75.
Defontis M Richartz J Engelmann N Bauer C Schwierk VM Büscher P Moritz A 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2012,41(3):369-374
A 9‐year‐old male Jack Russell Terrier with a history of travel to Thailand was presented with chronic lethargy, weight loss, unilateral anterior uveitis, pancytopenia, hyperglobulinemia, and proteinuria. Numerous trypomastigotes were found on a blood smear, and using molecular methods the parasite was identified as Trypanosoma evansi. After initial response to treatment, the dog experienced a relapse with central neurologic signs 88 days after initial presentation and died. Antibodies to T evansi were detected in both serum and cerebrospinal fluid (CSF) using a card agglutination test (CATT/T evansi), and PCR analysis of CSF for T evansi was positive. Findings at necropsy included marked non‐purulent meningoencephalitis. Chronic infection with T evansi in a dog that returned to Germany following international travel highlights the risk associated with introduction of foreign animal diseases to Europe and the possibility of these infections becoming endemic. Detection of chronic infection and curative therapy of trypanosomiasis are challenging, and infection is usually fatal in the dog. 相似文献
76.
77.
Janina Przybylska Zdzisława Zimniak-Przybylska 《Genetic Resources and Crop Evolution》1995,42(1):69-75
Summary Electrophoretic analysis of seed globulins was performed to investigate relationships between the Old-WorldLupinus species. The analysis covered 11 species described earlier and the recently reported taxon,Lupinus anatolicus nom. nud. With only two exceptions, particular species were represented by various accessions. In total, 110 accessions were examined.
SDS-PAGE of reduced globulins was carried out in a discontinuous buffer system.
The results showed a marked difference between the smooth-seeded and the rough-seeded species. In the group of smooth-seeded
lupins pronounced interspecific differences were recorded. The rough-seeded species formed a rather homogenous group, well
distinguishable from the smooth-seeded species. Though no distinct interspecific differences were recorded in the rough-seeded
group, most of the 34 investigatedL. atlanticus accessions could be distinguished due to a characteristic, prominent polypeptide band with approx. Mr 27 kDa. The recently reported smooth-seeded taxon,L. anatolicus, showed a species-specific SDS-PAGE globulin pattern.
Some of the presented results were announced in the form of a poster at the VIIth International Lupin Conference, Evora, Portugal,
April 18–23,1993. 相似文献
78.
Increasing the concentration of inorganic N increases the concentration of α-amino-N compounds in roots of hydroponically-grown sugar beet plants. These concentrations can, however, be reduced by increasing the concentration of sulphate in the nutrient solution. 相似文献
79.
Claudin-5 is an endothelium-specific tight junction protein. The aim of the present study was to detect the expression pattern of this molecule in intact pancreatic tissues and in well-differentiated and poorly differentiated pancreatic acinar cell carcinomas from dogs by the use of cross-reactive humanised anticlaudin-5 antibody. The necropsy samples taken from dogs included 10 nonneoplastic pancreatic tissues, 10 well-differentiated pancreatic acinar cell carcinomas, 10 poorly differentiated pancreatic acinar cell carcinomas, 5 intrahepatic metastases of well-differentiated and 5 intrahepatic metastases of poorly differentiated acinar cell carcinomas. A strong lateral membrane claudin-5 positivity was detected in exocrine cells in all intact pancreas samples. The endocrine cells of the islets of Langerhans and the epithelial cells of the ducts were negative for claudin-5. The endothelial cells of vessels and lymphatic channels in the stroma of the intact pancreas showed strong membrane positivity for this claudin. All well-differentiated exocrine pancreas carcinomas and all poorly-differentiated pancreatic acinar cell carcinoma samples showed a diffuse loss of claudin-5 expression. The claudin-5-positive peritumoural vessels and lymphatic channels facilitated the detection of vascular invasion of the claudin-5-negative cancer cells. In liver metastasis samples, the pancreatic carcinomas were negative for claudin-5. It seems that the loss of expression of claudin-5 may lead to carcinogenesis in canine exocrine pancreatic cells. 相似文献
80.
Agnieszka Kwiatkowska-Stenzel Janina SowińskaDorota Witkowska 《Journal of Equine Veterinary Science》2014
The aim of this study was to determine quantitative and qualitative occurrence of noxious gas compounds in the stable, depending on the time of the day (4:00 AM, 12:00, 8:00 PM), the height (20 cm, 150 cm), and the place (boxes, aisle) from which the samples were collected. Seven compounds were analyzed (NH3, SO2, COS, HCN, CH4, NO2, and CO). For analyzing stable air, a mobile gas analyzer was used. The time of day was a significant differential factor (P < .01) for concentrations of NH3, COS, and CH4. The highest concentrations of CH4, COS, NO2, NH3, and CO appeared at 4:00. For the rest of the studied compounds (SO2, HCN, CO) differences were not statistically significant, but there was a tendency for the highest concentrations at 12:00. The concentrations of gas compounds depending on height did not differ significantly from each other, but there was a tendency for higher concentrations of NH3, SO2, CH4, and CO at 150 cm and for HCN at 20 cm. COS and NO2 remained constant at both heights in boxes. The places where the samples were collected was a significant differential factor (P < .01) for NH3 and SO2. For the rest of the studied compounds the differences were not statistically significant. It can be concluded that many noxious compounds may appear without being noticed, and that is why it is necessary to provide stables with efficient air exchange throughout the day. 相似文献