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91.
SUMMARY Subclinical nutritional myopathy was induced in 5-month-old sheep by feeding them a diet low in vitamin E and selenium. Subsequently clinical myopathy was induced by dosing with protected polyunsaturated fatty acids. Plasma activities of creatine kinase (CK), pyruvate kinase, aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase and aldolase, enzymes of muscle origin, all remained above their reference ranges in clinically affected sheep, but fluctuated widely. Similar fluctuations occurred in subclinically affected animals, resulting in some activities being within the reference ranges and some above, at different times. Plasma malondialdehyde, an indicator of lipid peroxidation, proved of no diagnostic value. Terminal plasma CK activities were significantly correlated with microscopic damage in the vastus lateralis (VL), but not the vastus intermedius (VI) or the tensor fascia lata (TFL) muscles. AST was the most highly correlated with damage in VI and VL. In two clinically affected sheep successfully treated with an oral dose of α-tocopherol actetate all enzymes decreased steadily to within their reference ranges, at rates probably related to their plasma half-lives. These results suggest that measurement of plasma CK activity would be useful in monitoring recovery of treated sheep. 相似文献
92.
Perez, R., Cox, J.F., Arrue, R. Probable post-synaptic ot2 adrenergic mediated effect of xylazine on goat uterine motility. J. vet. Pharmacol. Therap. 17 , 59–63. Xylazine has been characterized as a selective α2-adrenoceptor agonist, which has explained its central nervous system depressant and other pharmacological effects. In order to characterize the effect of xylazine on uterine motility during the oestrus cycle in goats intrauterine pressure changes were recorded in cycling goats using balloon-tipped catheters placed in the uterine horns and connected to pressure transducers and a recorder. The effect of xylazine on myometrial activity was studied by giving increasing doses of the drug (1.0, 10.0, 100.0 or 500.0 m̈g/kg) intravenously (i.v.) to animals either in the follicular or the luteal phase of the cycle. To establish the subtype of a adrenergic receptor mediating the action of xylazine, goats were pretreated with either prazosin (1.0 mg/kg, i.v.) or yohimbine (1.0 m̈g/kg, i.v.). To establish whether the effect of xylazine was pre- or post-synaptic, xylazine (100 mg/kg, i.v.) was administered to goats pretreated with reserpine (0.8 mg/kg, i.p.) to deplete presynaptic catecholamine stores. Xylazine induced a significant and dose-dependent increase on uterine motility in cycling goats, apparently mediated by postsynaptic oc2-adrenoceptors. 相似文献
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DJ Hutchinson EM Jones JM Pay JR Clarke MT Lohr JO Hampton 《Australian veterinary journal》2023,101(8):313-319
There is a growing recognition of the harmful effects of lead exposure on avian and mammalian scavengers. This can lead to both lethal and non-lethal effects which may negatively impact wildlife populations. Our objective was to assess medium-term lead exposure in wild Tasmanian devils (Sarcophilus harrisii). Frozen liver samples (n = 41), opportunistically collected in 2017–2022, were analysed using inductively coupled plasma mass spectrometry (ICP-MS) to determine liver lead concentrations. These results were then used to calculate the proportion of animals with elevated lead levels (>5 mg/kg dry weight) and examine the role of explanatory variables that may have influenced the results. The majority of samples analysed were from the south-east corner of Tasmania, within 50 km of Hobart. No Tasmanian devil samples were found to have elevated lead levels. The median liver lead concentration was 0.17 mg/kg (range 0.05–1.32 mg/kg). Female devils were found to have significantly higher liver lead concentrations than males (P = 0.013), which was likely related to lactation, but other variables (age, location, body mass) were not significant. These results suggest that wild Tasmanian devil populations currently show minimal medium-term evidence of exposure to lead pollution, although samples were concentrated in peri-urban areas. The results provide a baseline level which can be used to assess the impact of any future changes in lead use in Tasmania. Furthermore, these data can be used as a comparison for lead exposure studies in other mammalian scavengers, including other carnivorous marsupial species. 相似文献
95.
The effects of cutting height (20 and 44 mm), frequency (once every 2 weeks April-September inclusive and twice a year) and seed rate (250 and 20 kg ha-1 ) on the water use and herbage yield of perennial ryegrass swards, for 3 years after sowing, were compared.
Frequent cutting and a low cutting height reduced water use in the first year only. In later years infrequent cutting led to higher yields and higher water-use efficiencies, but did not affect total water use or the shape of the soil water profile. Seed rate influenced sward composition and the pattern of water use, but not total water use. The swards from the low seed rate had a lower stubble biomass and tiller density, and extracted relatively more water at depths of 75 and 85 cm and less at depths of 15 and 35 cm, than the swards derived from the high seed rate.
The ratio of actual: potential evapotranspiration was reduced as the soil water deficit increased and was lowest in the summer after a dry spring. Cutting height and frequency during summer were shown not to be effective methods of either conserving water or manipulating the effective rooting depth of an established sward. 相似文献
Frequent cutting and a low cutting height reduced water use in the first year only. In later years infrequent cutting led to higher yields and higher water-use efficiencies, but did not affect total water use or the shape of the soil water profile. Seed rate influenced sward composition and the pattern of water use, but not total water use. The swards from the low seed rate had a lower stubble biomass and tiller density, and extracted relatively more water at depths of 75 and 85 cm and less at depths of 15 and 35 cm, than the swards derived from the high seed rate.
The ratio of actual: potential evapotranspiration was reduced as the soil water deficit increased and was lowest in the summer after a dry spring. Cutting height and frequency during summer were shown not to be effective methods of either conserving water or manipulating the effective rooting depth of an established sward. 相似文献
96.
CASE HISTORY: A neonatal Thoroughbred foal was presented with rib fractures and left forelimb lameness secondary to dystocia. CLINICAL FINDINGS: The foal developed a head tilt, seizures and watery diarrhoea during hospitalisation and died at 7 days of age. Histological examination of the brain and spinal cord revealed a suppurative meningoencephalomyelitis with vasculitis, and numerous intralesional, gram-negative bacilli. Similar microscopic lesions were noted in the lungs, renal medullary interstitium, and umbilicus. Bacilli in the brain, spinal cord and umbilicus were identified immunohistochemically as Salmonella group B. Salmonella agona was isolated in pure culture from the brain, lung, liver, kidney, and intestine. CONCLUSION: This is the first report of meningoencephalomyelitis and septicaemia due to Salmonella infection in an equine neonate. 相似文献
97.
Extract Listeria monocytogenes is widely distributed in the environment of farm animals. It is found in soil, faeces and nasal secretions of healthy animals, water troughs and animal feeds. Under certain conditions it becomes pathogenic, causing serious disease in cattle and sheep. Most commonly it causes meningoencephalitis but, on occasion, septicaemic listeriosis results in abortion, and more recently it has been associated with gastroenteritis. 相似文献
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99.
Testosterone serum profile,semen characteristics and testicular biometry of Mangalarga Marchador stallions in a tropical environment
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B Waddington JM Penitente‐Filho JGS Neves RO Pinho AY Chaya PP Maitan CO Silveira MG Neves SEF Guimarães GR de Carvalho JD Guimarães 《Reproduction in domestic animals》2017,52(2):335-343
This study was conducted to characterize the daily profile of testosterone secretion and its mean concentrations in the four seasons as well as to evaluate the semen characteristics and testicular biometry of Mangalarga Marchador stallions throughout the year in a tropical region. Three stallions were submitted to semen collections and evaluation of testicular biometry every 14 days along a year. Blood samples were collected once at the middle of each season, in a 20‐min interval during 24 hr in order to evaluate the testosterone secretion profiles among seasons. Testosterone concentrations along the day were higher at the beginning of the afternoon (from 12:00 to 15:00 hr), but a circadian secretion was not clearly observed. Mean testosterone concentrations did not differ among seasons (p > .05), but a pattern of secretion along the day showed variations with higher concentrations in the afternoon during the winter. Ejaculate volume was higher during summer; however, sperm motility decreased in summer and spring. Total sperm in ejaculate, sperm morphology and testicular biometry kept constant along the year showing no differences among the seasons. The results demonstrated that in a tropical region, reproductive aspects of stallions did not show a clearly defined seasonal variation, and months of autumn and winter were not unsuitable for reproduction of the males. 相似文献
100.
Dinoflagellates are single-celled organisms that reflect the ecological conditions in modern oceans and lakes. Ultrastructural data and molecular phylogeny suggest that they originated in the Neoproterozoic, yet dinoflagellate ancestors are classified only to the Middle Triassic ( approximately 240 million years ago). Examination of dinoflagellate-specific biological markers (dinosteranes and 4alpha-methyl-24-ethylcholestane) in concentrated microfossils with known morphology identified ancient dinoflagellate ancestors from the Early Cambrian ( approximately 520 million years ago). 相似文献