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排序方式: 共有114条查询结果,搜索用时 15 毫秒
111.
Elisa Peripolli Nedenia Bonvino Stafuzza Sabrina Thaise Amorim Marcos Vinícius Antunes de Lemos Laís Grigoletto Sabrina Kluska José Bento Sterman Ferraz Joanir Pereira Eler Elisângela Chicaroni Mattos Fernando Baldi 《Zeitschrift für Tierzüchtung und Züchtungsbiologie》2020,137(2):155-165
The aim of this study was to assess the distribution of runs of homozygosity (ROH) and autozygosity islands in the composite Montana Tropical® beef cattle to explore hotspot regions which could better characterize the different biological types within the composite breed. Montana animals (n = 1,436) were genotyped with the GGP-LD BeadChip (~30,000 markers). ROH was identified in every individual using the plink v1.90 software. Medium and long ROH prevailed in the genome, which accounted for approximately 74% of all ROH detected. On an average, 2.0% of the genome was within ROH, agreeing with the pedigree-based inbreeding coefficient. The Montana cattle with a higher proportion of productive breed types showed the highest number of autozygosity islands (n = 17), followed by those with a higher proportion of breeds adapted to tropical environments (n = 15). Enriched terms (p < .05) associated with the immune and inflammatory response, homeostasis, reproduction, mineral absorption, and lipid metabolism were described within the autozygosity islands. In this regard, over-represented GO terms and KEGG pathways described in this population may play a key role in providing information to explore the genetic and biological mechanisms together with the genomic regions underlying each biological type that favoured their optimal performance ability in tropical and subtropical regions. 相似文献
112.
M.H.A. Santana Y.T. Utsunomiya H.H.R. Neves R.C. Gomes J.F. Garcia H. Fukumasu S.L. Silva P.R. Leme L.L. Coutinho J.P. Eler J.B.S. Ferraz 《Zeitschrift für Tierzüchtung und Züchtungsbiologie》2014,131(3):210-216
The genome‐wide association study (GWAS) results are presented for average daily gain (ADG) in Nellore cattle. Phenotype of 720 male Bos indicus animals with information of ADG in feedlots and 354 147 single‐nucleotide polymorphisms (SNPs) obtained from a database added by information from Illumina Bovine HD (777 962 SNPs) and Illumina BovineSNP50 (54 609) by imputation were used. After quality control and imputation, 290 620 SNPs remained in the association analysis, using R package Genome‐wide Rapid Association using Mixed Model and Regression method GRAMMAR‐Gamma. A genomic region with six significant SNPs, at Bonferroni‐corrected significance, was found on chromosome 3. The most significant SNP (rs42518459, BTA3: 85849977, p = 9.49 × 10?8) explained 5.62% of the phenotypic variance and had the allele substitution effect of ?0.269 kg/day. Important genes such as PDE4B, LEPR, CYP2J2 and FGGY are located near this region, which is overlapped by 12 quantitative trait locus (QTLs) described for several production traits. Other regions with markers with suggestive effects were identified in BTA6 and BTA10. This study showed regions with major effects on ADG in Bos indicus in feedlots. This information may be useful to increase the efficiency of selecting this trait and to understand the physiological processes involved in its regulation. 相似文献
113.
The objective of the present study was to define an alternative contemporary group structure that would permit an increase in the number of records to be included in genetic evaluations with minimal bias. For this purpose, using different criteria as goodness of fit measured by percentages of squared bias, correlations between predicted and observed records, residual variances, genetic trends, rank correlations, and a practical situation of genetic evaluation, an animal model with standard contemporary group structure was compared with a model with alternative contemporary group structure including weaning management group (WMG) as an additional uncorrelated random effect for postweaning growth traits of composite beef cattle. The present study showed that the inclusion of WMG as a random effect in the statistical model for postweaning growth traits has only a small impact on animal ranking and a small or no impact on the estimation of genetic parameters and genetic trends. On the other hand, this approach leads to an important increase in the number of records available for the prediction of genetic merit with minimal or even no bias. Therefore, the model proposed here can be recommended to overcome problems related to loss of data of model with standard contemporary group structure. 相似文献
114.
Ferraz G Nichols JD Hines JE Stouffer PC Bierregaard RO Lovejoy TE 《Science (New York, N.Y.)》2007,315(5809):238-241
As compared with extensive contiguous areas, small isolated habitat patches lack many species. Some species disappear after isolation; others are rarely found in any small patch, regardless of isolation. We used a 13-year data set of bird captures from a large landscape-manipulation experiment in a Brazilian Amazon forest to model the extinction-colonization dynamics of 55 species and tested basic predictions of island biogeography and metapopulation theory. From our models, we derived two metrics of species vulnerability to changes in isolation and patch area. We found a strong effect of area and a variable effect of isolation on the predicted patch occupancy by birds. 相似文献