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991.
OBJECTIVES: To evaluate the high incidence of tibial tuberosity avulsion fracture diagnosed in skeletally immature Staffordshire bull terriers presenting to a UK animal welfare charity hospital. METHODS: A retrospective review of tibial tuberosity avulsion fractures treated by the hospital between 2002 and 2007. RESULTS: Sixty-five tibial tuberosity avulsion fractures were recorded in 59 dogs. Fifty-one tibial tuberosity avulsion fracture-affected dogs (86 per cent) were Staffordshire bull terriers. Dogs sustaining tibial tuberosity avulsion fractures had median and mean ages of five and 4.9 months, respectively (range three to 10 months). Where recorded, injury was associated with a short fall or jump (typically 3 to 4 feet) in 29 of 50 dogs. Three fracture patterns were recorded: 37 stifles sustained isolated tibial tuberosity avulsion fracture; 15 stifles sustained tibial tuberosity avulsion fracture accompanied by separation of the proximal tibial epiphysis; in 13 stifles epiphyseal separation extended to produce Salter-Harris type II fracture of the caudal tibial metaphysis. On analysis of the hospital database, tibial tuberosity avulsion fracture was a reason for presentation in 51 (3.3 per cent) of 1536 Staffordshire bull terriers, but only five (0.18 per cent) of 2815 other breed dogs, registered under the age of 12 months during the study period (P<0.001). CLINICAL SIGNIFICANCE: Staffordshire bull terriers commonly present with tibial tuberosity avulsion fracture, with or without concurrent separation of the proximal tibial epiphysis, to this urban charity hospital. 相似文献
992.
A factorial experiment (3 x 4 x 2 x 3) was conducted in programmable incubators to investigate interaction between the effects of rainfall amount, rainfall distribution and evaporation rate on development of Haemonchus contortus to L3. Sheep faeces containing H. contortus eggs were incubated on sterilised soil under variable temperatures typical of summer in the Northern Tablelands of NSW, Australia. Simulated rainfall was applied in 1 of 3 amounts (12, 24 or 32 mm) and 4 distributions (a single event on the day after deposition, or the same total amount split in 2, 3 or 4 equal events over 2, 3 or 4 days, respectively). Samples were incubated at either a Low or High rate of evaporation (Low: 2.1-3.4 mm/day and High: 3.8-6.1 mm/day), and faeces and soil were destructively sampled at 4, 7 and 14 days post-deposition. Recovery of L3 from the soil (extra-pellet L3) increased over time (up to 0.52% at day 14) and with each increment of rainfall (12 mm: <0.01%; 24 mm: 0.10%; 32 mm: 0.45%) but was reduced under the High evaporation rate (0.01%) compared with the Low evaporation rate (0.31%). All rainfall amounts yielded significantly different recoveries of L3 under Low evaporation rates but there was no difference between the 12 and 24 mm treatments under the High evaporation rate. The distribution of simulated rainfall did not significantly affect recovery of infective larvae. Faecal moisture content was positively associated with L3 recovery, as was the ratio of cumulative precipitation and cumulative evaporation (P/E), particularly when measured in the first 4 days post-deposition. The results show that evaporation rate plays a significant role in regulating the influence of rainfall amount on the success of L3 transmission. 相似文献
993.
994.
Mavangira V Evans TJ Villamil JA Hahn AW Chigerwe M Tyler JW 《Journal of the American Veterinary Medical Association》2008,233(6):955-959
OBJECTIVE: To determine associations between age, sex, breed, and month and year of admission and the diagnosis of lead toxicosis in cattle. DESIGN: Retrospective case-control study. Sample Population-Records of all cattle evaluated at North American veterinary teaching hospitals during the years 1963 to 2002, which were available through the Veterinary Medical Database. PROCEDURES: Logistic regression was used to evaluate the associations between postulated risk factors and the occurrence of lead toxicosis in cattle and predict the occurrence of the diagnosis of lead toxicosis in cattle. RESULTS: 413 cases of lead intoxication and 202,363 control cattle were identified and met the inclusion criteria. Cattle < 4 years of age were at increased risk for the diagnosis of lead intoxication relative to cattle > or = 4 years of age. Cattle > or = 2 months and < 6 months of age had the greatest risk for lead intoxication (odds ratio, 12.3). Angus cattle were at greater risk for toxicosis (odds ratio, 1.95), compared with other breeds. The risk of lead toxicosis was greater before 1985 (odds ratio, 1.94) than the risk thereafter. The risk of lead toxicosis diagnosis was greatest in the months of May, June, July, and August. CONCLUSIONS AND CLINICAL RELEVANCE: Lead toxicosis in cattle was associated with age < 4 years and the Angus breed. A seasonal pattern existed with peak occurrence in the late spring and summer. The occurrence of lead toxicosis has declined over time. 相似文献
995.
J. M. Naylor A. W. A. Saman Abeysekara A. W. A. Wassef U. Isak G. A. Zello 《Journal of animal physiology and animal nutrition》2008,92(2):221-221
D-lactic acidosis occurs as a complication of short-bowel syndrome in humans and in a variety of other gastrointestinal disorders in monogastrics and ruminants. It is associated with signs of impaired central nervous system (CNS) function including ataxia and coma. The objective of this experiment was to determine if either acidification of nervous tissue or D-lactic acid is responsible for decreased neurological function. Eight Holstein calves (32 ± 11 d) were surgically catheterized with indwelling intravenous jugular and atlanto-occipital space cerebrospinal fluid (CSF) catheters and infused for 6 h in random order with iso-molar DL-lactic acid (DL-LA), L-lactic acid (L-LA), hydrochloric acid (HCl) or saline. DL-LA induced ataxia after 4 h of infusion and produced the greatest obtunding of CNS function (at 7 h, score 8.0 ± 0.4), whereas, the other infusions caused neither ataxia nor scores over 1.5 (p < 0.01 from DL-LA). After 6 h, DL-LA induced significantly less acidemia than HCl (pH 7.13 ± 0.06 and 7.00 ± 0.04, base excess −16 ± 1 and −23 ± 3 mmol/l, bicarbonate 11 ± 1 and 8 ± 1 mmol/L respectively, all p < 0.01), but greater than L-LA and saline (p < 0.01). CSF changes followed a similar but less pronounced pattern. Although HCl infusion produced a severe acidemia and CSF acidosis, only minor effects on neurological function were evident suggesting that D-lactate has a direct neurotoxic effect that is independent of acidosis. Conversely, L-LA produced only minor neurological changes. 相似文献
996.
K Kikuchi N Kashiwazaki T Nagai M Nakai T Somfai J Noguchi H Kaneko 《Reproduction in domestic animals》2008,43(S2):401-406
In vitro fertilization (IVF) of in vitro matured (IVM) oocytes in pigs has become the most popular method of studying gametogenesis and embryogenesis in this species. Furthermore, because of recent advances in in vitro culture (IVC) of IVM–IVF embryos, in vitro production (IVP) of embryos now enables us to generate viable embryos as successfully as for in vivo -derived embryos and with less cost and in less time. These technologies contribute not only to developments in reproductive physiology and agriculture but also to the conservation of porcine genetic resources and the production of cloned or genetically modified pigs. However, in IVP, there still remains the problem of abnormal ploidy, which is caused by performing procedures under non-physiological conditions. In recent years, unique technologies such as intracytoplasmic sperm injection (ICSI) or xenografting of gonadal tissue into immunodeficient experimental animals have been developed to help conserve gamete resources. These technologies combined with IVP are expected to be useful for the conservation of gametes from important genetic resources. Here, we discuss the developmental ability and normality of porcine IVP embryos and also the utilization of ICSI and xenografting in advancing biotechnology in pigs. 相似文献
997.
Objective To determine ocular distribution and toxicity of a single injection of intravitreal triamcinolone acetonide (TA) in normal horses.
Animals studied Six adult horses, donated to North Carolina State University.
Procedures Six horses were injected intravitreally with either 10, 20, or 40 mg ( n = 2 each) of TA. The opposite eye of each horse was injected with balanced salt solution (BSS). Ocular toxicity was assessed by biomicroscopy, tonometry, indirect ophthalmoscopy, and electroretinogram. Aqueous humor (AH), vitreous humor (VH), and plasma samples were collected. Horses were euthanized 7 or 21 days after injection and eyes enucleated for histopathology. TA concentrations in AH, VH, and plasma were measured by HPLC.
Results Three control eyes and one TA eye developed inflammation after injection or collection of AH. Positive bacterial cultures ( Corynebacterium spp., Staphylococcus spp., and Streptococcus spp.) were obtained from three of these eyes. Other than transient corneal edema in TA injected eyes, which resolved by 7 days after injection, no other changes were observed. TA crystals were visible within the vitreous body. No evidence of TA toxic effect was noted on histopathology. TA was detected in all AH and VH samples from treated eyes following injection. Drug was not detected in the plasma.
Conclusions There was no evidence of overt toxicity from intravitreal TA in normal horses and a single intravitreal injection resulted in TA ocular levels for 21 days. However, the risk for bacterial infections with intravitreal injection or anterior chamber aspirations in horses is high. Use of topical and systemic antibiotics after injection is recommended. 相似文献
Animals studied Six adult horses, donated to North Carolina State University.
Procedures Six horses were injected intravitreally with either 10, 20, or 40 mg ( n = 2 each) of TA. The opposite eye of each horse was injected with balanced salt solution (BSS). Ocular toxicity was assessed by biomicroscopy, tonometry, indirect ophthalmoscopy, and electroretinogram. Aqueous humor (AH), vitreous humor (VH), and plasma samples were collected. Horses were euthanized 7 or 21 days after injection and eyes enucleated for histopathology. TA concentrations in AH, VH, and plasma were measured by HPLC.
Results Three control eyes and one TA eye developed inflammation after injection or collection of AH. Positive bacterial cultures ( Corynebacterium spp., Staphylococcus spp., and Streptococcus spp.) were obtained from three of these eyes. Other than transient corneal edema in TA injected eyes, which resolved by 7 days after injection, no other changes were observed. TA crystals were visible within the vitreous body. No evidence of TA toxic effect was noted on histopathology. TA was detected in all AH and VH samples from treated eyes following injection. Drug was not detected in the plasma.
Conclusions There was no evidence of overt toxicity from intravitreal TA in normal horses and a single intravitreal injection resulted in TA ocular levels for 21 days. However, the risk for bacterial infections with intravitreal injection or anterior chamber aspirations in horses is high. Use of topical and systemic antibiotics after injection is recommended. 相似文献
998.
S. Gde J. Bennewitz K. Kirchner H. Looft P.W. Knap G. Thaller E. Kalm 《Livestock Science》2008,114(1):31-41
Data from 32 nucleus and multiplier herds in Germany was used to estimate variance components and breeding values for five maternal behaviour traits in sows. The estimation was performed univariately using an animal threshold model. About 31,000 farrowings recorded from December 2003 until July 2005 were included. The heritability coefficients were 0.07 (0.06) for group behaviour, 0.06 (0.03) for attitude to people, 0.05 (0.01) for maternal ability, 0.03 (0.01) for crushing of piglets and 0.02 (0.02) for savaging of piglets. Additionally, genetic correlations between the behaviour traits and between the behaviour traits and litter size, respectively, were estimated multivariately by REML with a linear model. Low heritability and weak genetic correlation to litter size at birth indicate that it may be difficult to genetically improve the maternal behaviour, and that selection for better mothering ability is not necessarily accompanied by reduced litter size at birth. 相似文献
999.
1000.
An increasing number of Dutch dairy farmers have diversified their activities, often opening their farm up to visitors (tourist accommodation, farm shop, contact with livestock, etc). It is essential to prevent these visitors from having accidents or becoming ill, which could result in financial claims and might harm the reputation of the agricultural sector. This article describes how the hazard analysis critical control points concept and principles (HACCP) can be applied to these activities and integrated with on-farm operational herd health and production management programmes. 相似文献