Assessment of the potential toxicity of a poison for rabbits, pindone (2-pivalyl 1, 3 indandione), to domestic animals

The toxicity of pindone, a rabbit poison, to horses, cattle, goats, chickens, dogs and cats was investigated, using extension of prothrombin time (PT) as an index of poisoning. The daily dose of pindone, administered for 5 days, ranged from 0.3 mg/kg for dogs to 2.5 mg/kg for chickens. This range of dose rates was considered to be indicative of the worst possible case that could arise following a campaign of baiting for rabbits. Although significant elevations in PT (more than double baseline values) were noted in all species other than horses, clinical signs of anticoagulant poisoning were not observed in any of the species tested. From the observed PT, cattle and cats appeared to be the most susceptible, and horses the least susceptible, to pindone toxicity. The half-lives of the elevated PT were calculated as 3.1 days for cattle, 2.8 days for goats and chickens, 1.9 days for horses and dogs and less than one day for cats. It is proposed that these half-lives can be used as a guide for determining the duration of treatment of pindone-affected animals.     

Prosthetic Coxofemoral Joint Replacement in the Goose (Anser Sp.): II. Histologic and Mechanical Interface Evaluations

The interfacial tissue-implant healing reactions have been investigated in the goose to evaluate its suitability as an animal model for joint replacement implant studies. After various implantation periods, geese with one coxofemoral replacement hemiarthroplasty were evaluated for their gait performance and then sacrificed. The implantation sites and femora with implants were subjected to histologic studies, and the interfacial shear strength between the bone and implant was measured. The results were compared with findings reported in the literature on dog and man. Direct bone apposition was found in two geese with a firmly fixed implant. A connective tissue capsule surrounded those seven implant stems that were found to sit loosely in the femoral canal. Whereas the histologic findings were comparable to findings in dog and man, the interfacial shear stress was somewhat lower in the goose. Because of the histopathologically comparable findings of interfacial healing, the goose appears to present a suitable model to study bone implant tissue reactions. Further studies are necessary to determine seasonal-, age-, and sex-related bone tissue differences in the goose.     

What you can and cannot learn from reading a vaccine label.

Although most veterinarians look at vaccine labels each day, they rarely see them. When practitioners sense a need to read labels, they find that the labeling answers some of their basic questions but that these labels often fail to address many relevant issues. In addition, veterinarians find that the issues addressed are often presented simplistically and that the labels are sometimes just wrong. This article addresses what practitioners need to do to better understand the products most of them use on a daily basis.     

如何提高仔猪饲料中小麦的利用率

<正>用最具成本效益的方法配制猪饲料是提高养猪场经济利润的一种重要手段。但是,具有最低成本的饲料配制方法往往会就几种主要饲料原料的饲喂价值进行过于简单的假设,同时还假定各饲料原料的养分具有相加性。这种情况会因饲料添加剂的加入而进一步混乱,或受到潜在的损害,因为饲料添加剂旨在使饲料释放更多的能量和/或氨基酸。因此,饲料配方师不得不充分确保某种添加剂将持