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We present a case of aggressive metastatic carcinoma in a horse that was initially presented for shoulder lameness. Although radiography and scintigraphy were useful for localising a lesion in the proximal humerus, subsequent development of non-specific signs of systemic disease prompted further evaluation. Haematology and blood biochemistry, urinalysis and ultrasonography were all instrumental in identifying renal involvement. A diagnosis of a peri-renal mass causing secondary renal failure prompted euthanasia of the horse because of the poor prognosis. Antemortem findings were supported by necropsy, with secondary lesions also identified in the spleen, liver, 8th left rib and proximal humerus. Histological examination yielded a diagnosis of undifferentiated metastatic carcinoma. 相似文献
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Pregnancy Rates to Fixed Embryo Transfer of Vitrified IVP Bos indicus,Bos taurus or Bos indicus × Bos taurus Embryos 下载免费PDF全文
LSR Marinho BV Sanches CO Rosa JH Tannura AG Rigo AC Basso JHF Pontes MM Seneda 《Reproduction in domestic animals》2015,50(5):807-811
The pregnancy rates obtained after the transfer of cryopreserved in vitro‐produced (IVP) embryos are usually low and/or inconsistent. The objective of this study was to evaluate the pregnancy rates of Holstein, Gyr and Holstein × Gyr cattle after the transfer of vitrified IVP embryos produced with X‐sorted sperm. Seventy‐two Gyr and 703 Holstein females were subjected to ovum pickup (OPU) sessions, followed by in vitro embryo production using semen from sires of the same breeds. Embryos (1636 Holstein, 241 Gyr and 1515 Holstein × Gyr) were exposed to forskolin for 48 h prior to vitrification. The pregnancy rate achieved with Gyr dam and sire was 46.1%, which was similar (p = 0.11) to that of Holstein dam and Gyr sire (40.3%). Crossing Gyr dams with Holstein sires resulted in a pregnancy rate of 38.9% and did not differ (p = 0.58) from the pregnancy rate obtained with the cross between Holstein dams and Gyr sires. The rate obtained with Holstein dam and sire was 32.5%. The average pregnancy rate was 36.6%, and no difference was found in the proportion of female foetuses (88.8%, in average) among breeds (p > 0.05). In conclusion, transfer of cryopreserved X‐sorted embryos represents an interesting choice for dairy cattle. Despite the small differences between pregnancy rates, we highlight the efficiency of this strategy for all of the racial groups studied. 相似文献
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Estimating the development of the fennel aphid,Hyadaphis foeniculi (Passerini) (Hemiptera: Aphiididae), using non‐linear models 下载免费PDF全文
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C Yamada WB Feitosa R Simões AC Nicacio CM Mendes MEOA Assumpção JA Visintin 《Reproduction in domestic animals》2011,46(1):173-176
The current study examined the protective effects of l ‐glutamine and cytochalasin B during vitrification of immature bovine oocytes. Oocyte vitrification solution (PBS supplemented with 10% FCS, 25% EG, 25% DMSO and 0.5 m trehalose) was the vitrification control. Treatments were the addition of 7 μg/ml cytochalasin B, 80 mm glutamine or both cytochalasin and glutaminine for 30 s. After warming, oocytes were matured in vitro for 24 h, fixed and stained with Hoechst (33342) for nuclear maturation evaluation. l ‐glutamine improved the vitrified/warmed immature bovine oocytes viability (32.8%), increasing the nuclear maturation rates compared to other treatments and the no treatment vitrified control (17.4%). There was, however, no effect of cytochalasin B on in vitro maturation (14.4%). 相似文献
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Organisms allocate resources to male and female offspring in a process called sex allocation. In a Perspective, Stuart West and colleagues discuss what sex allocation tells us about evolution by natural selection and how sex allocation can be applied to understanding the mating structure of parasitic protozoans. 相似文献
48.
AC Fabian 《Science (New York, N.Y.)》1997,275(5296):48-49
The soft x-ray spectra of the Virgo and Coma clusters cannot be modeled by emission from the well-known hot intracluster medium attenuated by photoelectric absorption along the line of sight in our galaxy. If the excess soft emission is due to thermal emission in the clusters from gas at about 1 million kelvin, then the gas should be rapidly cooling. The high rate of cooling poses problems for the origin of the gas and its sink. A model in which the component is due to turbulent mixing layers around clouds scattered throughout the intracluster medium may explain the excess emission. The gas in the mixing layer is reheated after cooling, so that the total mass remains relatively small. 相似文献
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Abstract Extract Among the puzzling aspects of the recently described autosomal recessive polycystic kidney disease (ARPKD) of sheep (Johnstone et al 2005) is the multiplicity of organ systems affected and the phenotypic variations that occur between the various animal species. It has been shown in studies of other inherited polycystic kidney disease syndromes that the normal gene products of a mutant are likely to be involved in ciliary structure and function. The studies that have led to this recognition can be expected to eventually provide the basis for a better understanding of the functioning of this organelle, and the pathogenesis of lesions in the related diseases. It is well known that cilia are important in the perception of light, olfactory stimuli and sound and that motile cilia provide cell motility (e.g. sperm) and transport of mucus and other fluids. Recent research has indicated that the involvement of the primary cili-um/basal body complex is of central importance in the detection and cellular response to extracellular movement of fluid, critical phases of embryonic development, cell cycle regulation and maintenance of cell polarity. Confocal microscopic studies of renal cyst epithelium in ovine ARPKD have shown that only 30% of cells have a cilium and that these are often truncated (McGlashan et al 2005). The observation, although preliminary, strongly supports the argument that the mutant gene in this disease of sheep normally encodes for a protein essential for primary ciliary function. 相似文献
50.
Abstract Extract New Zealand is remarkable for the few species of tick that occur in the country and an apparent absence of tick-borne diseases. There is, however, only a lack of reports of locally-acquired infections which indicates tick-borne spotted fever group (SFG) rickettsias, ehrlichias, anaplasmas and bartonellas do not occur in the country (Roberts et al 2001). To provide more definitive information, we conducted a PCR survey on ticks from New Zealand. 相似文献