Genes for resistance to wheat powdery mildew in derivatives of Triticum timopheevi and T. carthlicum

Summary The winter wheat line TP 114 derived from CI 12633, a Triticum timopheevi derivative, has two unlinked dominant genes conditioning resistance to the powdery mildew fungus (Erysiphe graminis f. sp. tritici). One of the genes is identical to gene Pm2 (Ml _u ). The other gene differs from the eleven Pm and/or Ml designated genes; a temporary designation, Ml _f ,is proposed for this gene. Gene Ml _f is closely associated with a gene conditioning resistance to the stem rust fungus (Puccinia graminis f. sp. tritici), probably gene Sr9c.The winter wheat line TP 229 derived from Triticum carthlicum has one dominant mildew resistance gene identical to gene Ml _e in Weihenstephaner M 1.     

Immunity to colon cancer assessed by antigen-induced inhibition of mixed mononuclear cell migration

A purified preparation of mixed human peripheral blood lymphocytes and monocytes was used in an inhibition-of-migration assay for cell-mediated immunity to cancer of the colon. This preparation was reproducibly antigen-responsive and migrated with greater reliability than did a more complex cell mixture. Of 27 patients with this disease, cells from 24 showed inhibited migratio in response to colon carcinoma antigen. Uninhibited migration patterns were found in each of the 52 cancer-free controls, including eight patients with nonmalignant disease initially diagnosed as cancer of the colon, and in nine patients with surgically cured adenocarcinoma of the colon.