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51.
半滑舌鳎的性腺分化和温度对性别决定的影响 总被引:20,自引:2,他引:18
半滑舌鳎(Cynoglossus semilaevisGünther)是近年来新开发的一种理想的增养殖对象,雌性个体生长速度比雄性快2~3倍。由于温度可影响多种鱼类的性腺分化,因而探索温度对该鱼的性别决定和性腺分化的影响,获得性逆转雄性亲本,用于培育全雌后代,具有重要的应用前景和经济效益。通过石蜡组织切片,对半滑舌鳎早期性腺分化进行组织学观察。发现在24℃饲养条件下,孵化后30 d半滑舌鳎性腺开始分化,其中具有裂隙的性腺原基未来发育为卵巢,而不具裂隙的原基未来发育为精巢。在孵化后25~100 d对半滑舌鳎进行不同温度(16℃、20℃、24℃、28℃、32℃)处理,在9月龄时利用石蜡组织切片鉴定表型性别,观察温度对性腺分化的影响,结果表明,28℃和32℃高温能显著提高群体中的雄性比例,使其分别达到69.2%和66.7%;而低温16℃和20℃对性腺分化影响不大,群体中雄性比例分别为56.5%和57.1%;24℃处理群体中雌雄个体比例接近1∶1。半滑舌鳎雌性特异的遗传性别鉴定技术也检测到高温和低温处理组出现了由基因型雌性向表型雄性逆转的雄性个体。这些结果表明温度影响了半滑舌鳎性腺分化方向。 相似文献
52.
建立了6自由度6-3-3并联机构逆运动学模型,基于刚体动力学牛顿-欧拉法推导出了该机构逆动力学方程组,并用矩阵QR分解方法求解了该动力学方程组,给出了逆动力学仿真程序开发思路并通过Matlab软件加以实现,通过空载和有载荷作用条件下的算例仿真和分析比较,验证了该动力学模型的正确性. 相似文献
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Sijin Hang Hui Chen Wenhui Wu Shiyi Wang Yiwen Fang Ruilong Sheng Qidong Tu Ruihua Guo 《Marine drugs》2022,20(6)
Compound 1 (SMTP-7, also FGFC1), an isoindolone alkaloid from marine fungi Starchbotrys longispora FG216 and fungi Stachybotrys microspora IFO 30018, possessed diverse bioactivities such as thrombolysis, anti-inflammatory and anti-oxidative properties, and so on. It may be widely used for the treatment of various diseases, including cerebral infarction, stroke, ischemia/reperfusion damage, acute kidney injury, etc. Especially in cerebral infarction, compound 1 could reduce hemorrhagic transformation along with thrombolytic therapy, as the traditional therapies are accompanied with bleeding risks. In the latest studies, compound 1 selectively inhibited the growth of NSCLC cells with EGFR mutation, thus demonstrating its excellent anti-cancer activity. Herein, we summarized pharmacological activities, preparation of staplabin congeners—especially compound 1—and the mechanism of compound 1, with potential therapeutic applications. 相似文献
57.
Colorectal cancer, a malignant tumor with high mortality, has a poor prognosis due to drug resistance and toxicity in clinical surgery and chemotherapy. Thus, finding safer and more efficient drugs for clinical trials is vital and urgent. Natural marine compounds, with rich resources and original chemical structures, are applied widely in anticancer treatments. We provide a systematic overview of recently reported marine compounds such as alkaloids, peptides, terpenoids, polysaccharides, and carotenoids from in vitro, in vivo, and clinical studies. The in vitro studies summarized the marine origins and pharmacological mechanisms, including anti-proliferation, anti-angiogenesis, anti-migration, anti-invasion, the acceleration of cycle arrest, and the promotion of tumor apoptosis, of various compounds. The in vivo studies outlined the antitumor effects of marine compounds on colorectal cancer model mice and evaluated their efficacy in terms of tumor inhibition, hepatotoxicity, and nephrotoxicity. The clinical studies summarized the major chemical classifications and targets of action of the clinical drugs that have entered clinical approval and completed approval for marine anticancer. In summary, we present the current situation regarding the application of natural anti-colorectal cancer marine compounds and prospects for their clinical application. 相似文献
58.
Yujia Liu Yuli Qi Qi Wang Fawen Yin Honglei Zhan Han Wang Bingnan Liu Yoshimasa Nakamura Jihui Wang 《Marine drugs》2022,20(6)
Chlorella pyrenoidosa is an excellent source of protein, and in this research, we assessed the antioxidant and emulsifying effects of Chlorella protein hydrolysate (CPH) using neutral proteases and alkaline proteases, as well as the properties of CPH-derived krill oil-in-water (O/W) emulsions. The CPHs exhibited the ability to scavenge several kinds of free radicals, including 1,1-diphenyl-2-picrylhydrazyl (DPPH), O2−, hydroxyl, and ABTS. Additionally, the CPHs (5 mg/mL) scavenged approximately 100% of the DPPH and ABTS. The CPHs showed similar emulsifying activities to Tween 20 and excellent foaming activities (max FS 74%), which helped to stabilize the krill oil-in-water emulsion. Less than 10 mg/mL CPHs was able to form fresh krill oil-in-water emulsions; moreover, the CPHs (5 mg/mL) in a krill O/W emulsion were homogenous, opaque, and stable for at least 30 days. Based on their inhibitory effects on the peroxide value (POV) and thiobarbituric acid reactive substances (TRABS), the CPHs were found to be able to inhibit lipid oxidation in both emulsifying systems and krill O/W emulsions. Thus, the CPHs could improve superoxide dismutase (SOD) activities by 5- or 10-fold and decrease the high reactive oxygen species (ROS) level caused by the addition of H2O2 in vitro. In conclusion, health-promoting CPHs could be applied in krill oil-in-water emulsions as both emulsifiers and antioxidants, which could help to improve the oxidative and physical stability of emulsions. 相似文献
59.
GIS在广西龙眼种植优化布局中的应用 总被引:16,自引:1,他引:15
广西具有发展龙眼的适宜气候条件,却由于品种结构和区域布局不合理而没有取得理想的经济效益。为了优化广西龙眼区域布局和品种结构,根据龙眼的生物学特性及产量与气候要素的相关分析,筛选出龙眼生长发育的限制性气候要素,确定了龙眼种植的气候区划指标。利用广西89个站点的气候资料和1∶25万地形数据,建立了区划指标的空间分析模型。在GIS平台上按1 km×1 km细网格对区划指标进行了小网格推算,并利用反距离权重插值法对其残差部分进行空间内插;将推算结果和插值结果进行迭加,实现对区划指标小网格栅格数据的订正,使推算的结果更为精确。采用GIS技术对龙眼种植区进行气候区划,该区划按种植龙眼的气候适宜性,将广西划分为最适宜、适宜、次适宜和不适宜气候区,绘制了龙眼优化布局的细网格区划专题图。在此基础上,进一步对龙眼品种的优化布局问题进行研究探讨,给出了比较合理的早、中、晚熟品种的适宜种植范围,并分区进行评价和提出相应的建议。研究结果为广西龙眼生产提供了科学的依据。 相似文献
60.
Shijuan Yan Qing Liu Thomas Naake Wenjie Huang Mengyu Chen Qian Kong Sheng Zhang Wenyan Li Xuan Li Qinjian Liu Jianyuan Yang Alisdair R.Fernie Bin Liu 《作物学报(英文版)》2021,(4):725-738
Rice with panicle-blast resistance is needed for stable rice production. Although we have previously demonstrated that OsGF14b underlies a quantitative trait lo... 相似文献