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Ghorbanpoor M Razi Jalali MH Hoghooghi Rad N Nabavi L Esmail Zadeh S Rafiei A Haji Hajikolaei MR 《Veterinary parasitology》2006,142(1-2):91-94
Immunodiagnostic confirmation of cystic human hydatidosis is frequently required before surgical intervention or of chemotherapy. However, it remains inadequate to detect specific antibodies or antigens in some confirmed cases of echinococcosis. This study was carried out to investigate the accuracy of three different immunodiagnostic tests for detection of specific circulating antigens or antibodies in the serum and urine of 13 experimentally infected sheep. For this purpose, Echinococcus granulosus were collected from small intestine of experimentally infected dogs, and 2000 taenid eggs were orally administered to each of the 13 sheep. There were six other sheep, which were kept as the control group. Biweekly serum and urine samples were collected from all the sheep for 4 months after infection. The sera were subjected to indirect hemagglutination test and the concentrated urine samples were subjected to coagglutination and counter immunoelectrophoresis tests. The results revealed that the sensitivity of these tests in detecting the hydatid antigens in the urine or antihydatid antibodies in the serum of the infected sheep reached their maximum in 12th and 13th week after infection; then it decreased in the following weeks. Examination of the non-infected sheep samples throughout the experiment showed that the aforesaid findings were specific only to the infected sheep. It seems that the appearance of specific hydatid antigen in urine and its antibodies in the serum were simultaneous. Although these tests are highly specific, false negative outcomes were encountered in their detection of cystic echinococcosis. In general, it seems rational to establish some series of diagnostic procedures in order to reveal antibodies and antigen of metacestode in serum and urine of the patients. 相似文献
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CASE HISTORY: A mature male tuatara was presented with a history of recurrent cloacal prolapse. CLINICAL AND PATHOLOGICAL FINDINGS: The prolapsed tissue included a 12 mm diameter mass, which histologically showed cords and nodules of neoplastic epithelial cells. DIAGNOSIS: The mass was diagnosed as a squamous cell carcinoma with ulceration of the overlying stratified squamous epithelium and diffuse inflammation of the surrounding dermis. CLINICAL RELEVANCE: This case presented a rare opportunity to investigate squamous cell carcinoma in a long-lived lower vertebrate species. Future recurrence or metastasis of the mass may add useful information to the current base of knowledge of the behaviour of malignant neoplasms in reptiles. 相似文献
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CASE HISTORY: From 26 days of age, an Antipodes Island parakeet (Cyanoramphus unicolor) was noted to have a severe beak deformity and reduced bodyweight gain compared to its nest mate. The bird was euthanised at 43 days of age. CLINICAL AND PATHOLOGICAL FINDINGS: The beak abnormality consisted of distortion of the right nares and severe shortening resulting in deviation of the upper maxilla to the right and cranially. On sectioning the head, copious mucoid material was found in the infraorbital sinus and the bony sinus architecture was disrupted. Histopathological examination of the infraorbital sinuses revealed a large focus of chronic but active inflammation, bony lysis on the right side and pockets of a mixed population of bacteria. DIAGNOSIS: Severe beak deformity, likely secondary to bacterial sinusitis. CLINICAL RELEVANCE: The case illustrates the need to look for underlying aetiologies to beak malformation, particularly in young parrots. 相似文献
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Extract An adult male Jackson's chameleon died with a history of intermittent periorbital swelling, anorexia and abnormal posture. On post mortem examination, there were multiple granulomas in the tongue, liver and soft palate. Histopathology revealed chronic granulomatous inflammation with yeast-like organisms and non-septate branching hyphae. Fungal cultures resulted in the growth of a Penicillium spp that could not be speciated further. The peri-orbital tissues contained a mix of necrotic bone and muscle. Sections of the brain showed three large adjacent focal areas of infarction. The kidneys showed acute nephritis and sclerotic glomeruli. The cytoplasm of some renal tubular epithelial cells contained highly eosinophilic granules. This ‘sexual segment granulation’ is normal in sexually active males of some lizard species. 相似文献
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Abstract Extract The paper by Goodwin et al (2004) which appeared in the August 2004 issue of the New Zealand Veterinary Journal highlighted the prevalence and costs to the sheep industry of pneumonia in lambs. The costs are considerable, and the article begs the question, “what can sheep farmers do to reduce the effects of pneumonia in lambs?” 相似文献
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