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11.
Goldman MI 《Science (New York, N.Y.)》1967,155(3759):148-150
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Models predict that food-web structure is regulated by both consumers and resources, and the strength of this control is dependent on trophic position and food-web length. To test these hypotheses, a meta-analysis was conducted of 11 fish (consumer)-by-nutrient (resource) factorial plankton community experiments. As predicted, zooplankton biomass was under strong consumer control but was weakly stimulated by nutrient additions; phytoplankton biomass was under strong resource control with moderate control by fish. However, the phytoplankton and zooplankton responses to nutrient additions did not follow theoretical predictions based on the number of trophic levels in the food web. 相似文献
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Goldman KA 《Science (New York, N.Y.)》2000,290(5491):457-459
The safety and labeling of genetically engineered foods are two areas that have elicited considerable public concern and debate. This Policy Forum provides a legal analysis of these issues in the context of two bills that have been recently proposed in The U.S. Congress, the Genetically Engineered Food Safety Act and the Genetically Engineered Food Right to Know Act. Most transgenic components of foods currently on the market are plant-incorporated protectants or their inert ingredients. Therefore, they have been evaluated for safety by the Environmental Protection Agency (as well as the Food and Drug Administration), and their disclosure in labeling should not be required. If plant-incorporated protectants are considered safer than chemical pesticides, and chemical pesticides do not have to be disclosed in labels, then bioengineered foods should not be subject to stricter regulation, nor should they be required to be labeled. The two bills are inconsistent, in many respects, with well-established principles of food regulation. 相似文献
14.
During meiosis in Saccharomyces cerevisiae, DNA replication occurs 1. 5 to 2 hours before recombination initiates by DNA double-strand break formation. We show that replication and recombination initiation are directly linked. Blocking meiotic replication prevented double-strand break formation in a replication-checkpoint-independent manner, and delaying replication of a chromosome segment specifically delayed break formation in that segment. Consequently, the time between replication and break formation was held constant in all regions. We suggest that double-strand break formation occurs as part of a process initiated by DNA replication, which thus determines when meiotic recombination initiates on a regional rather than a cell-wide basis. 相似文献
15.
Abe Goldman 《Agriculture and Human Values》1991,8(1-2):99-113
The hazard of postharvest pest losses is ubiquitous in peasant farming systems; as a result, farmers invariably have some response to the threat of these losses. Responses to postharvest pests may be more extensive than to field pests, even when, by statistical measures, the usual levels of losses are comparable. In studies of pest management practices in three contrasting areas in Kenya, it was found that farmers virtually always rely on an array of techniques and strategies, usually including both older and more modern practices. There is considerable variation among regions in the techniques used, due not only to climatic and socioeconomic factors, but also to variations in cultural history and preferences. The ways in which management practices have changed over time also vary by region. The major changes have been related to overall system change. Four main sources of change have been paramount: (1) population growth and the intensification of land use; (2) the introduction of new cash crops; (3) the introduction of new marketing infrastructure; and (4) the perception of increased environmental risk. Their effect on the replacement of older practices by newer ones is often interrelated. Traditional techniques are often based on materials derived from bushland, but increasing population density makes these difficult to continue as bushland and its common property resources disappear. Simultaneously, tolerance for losses is reduced as land availability is constrained. With the introduction of a cash crop infrastructure, new methods of pest management, especially pesticide use, become more readily available and may spread rapidly. Areas with good market infrastructure but varying population density may still differ considerably because with abundant land it is possible to compensate for expected losses by additional planting. A study of an FAO project to improve postharvest management through earlier harvesting and a redesigned storage crib indicate some reasons for its lack of widespread acceptance. Little or no attempt was made to adapt techniques to varying circumstances; instead, a single “solution” was meant to be applied across areas of vastly different conditions. In many cases, this project represented a radical response to a problem farmers considered they were coping with acceptably using existing methods. Although it probably represents an improvement over traditional storage methods in purely technical terms, the new technique also often involved major costs, readjustments, and cultural disruptions that may not have been anticipated by its designers. More likely to succeed would be a strategy that begins with some of farmers' existing practices and whose objective is to develop and offer a range of possible improvements from which farmers could select individual components appropriate to their conditions and needs. 相似文献
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Goldman M 《Science (New York, N.Y.)》1996,273(5275):562b-564b
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20.
Differential inhibition of human platelet aggregation by selected Allium thiosulfinates 总被引:6,自引:0,他引:6
Briggs WH Xiao H Parkin KL Shen C Goldman IL 《Journal of agricultural and food chemistry》2000,48(11):5731-5735
Thiosulfinates (TSs) have been implicated as a principle source of the antiplatelet property of raw onion and garlic juice. The in vitro responses of human platelets to dosages of four TSs were measured using whole blood aggregometry and compared by regression analysis. Of the compounds evaluated, methyl methane-TS (MMTS), propyl propane-TS (PPTS), and 2-propenyl 2-propene-TS (allicin) are present in freshly cut Allium vegetables, whereas ethyl ethane-TS (EETS) has not been detected. All TSs were synthesized using a model reaction system. PPTS and allicin had the strongest antiplatelet activity at 0.4 mM, inhibiting aggregation by 90 and 89%, respectively. At the same concentration, EETS and MMTS were significantly weaker, inhibiting 74 and 26%, respectively. Combinations of TSs were not additive in their inhibition of aggregation, indicating that the antiplatelet potential of Allium extracts cannot be easily predicted by quantifying organosulfur components. EETS, PPTS, and allicin were significantly more potent platelet inhibitors than aspirin at nearly equivalent concentrations. 相似文献