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Lauren Bookbinder Carrie J. Finno Anna M. Firshman Scott A. Katzman Erin Burns Janel Peterson Anna Dahlgren Brittni Ming‐Whitfield Shelby Glessner Amanda Borer‐Matsui Stephanie J. Valberg 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2019,33(6):2770-2779
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Carrie Wohleb 《American Journal of Potato Research》2018,95(3):208-229
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Amber L. Labelle Ralph E. Hamor Anne M. Barger Carol W. Maddox† Carrie B. Breaux 《Veterinary ophthalmology》2009,12(1):48-52
An 8-year-old male castrated Domestic Short-haired cat was examined for a 1-week history of blepharospasm and mucoid ocular discharge OS. Examination revealed ulcerative keratitis with stromal loss, stromal infiltrate, corneal edema, perilimbal vascularization and miosis. Cytology of the cornea revealed multiple dichotomously branching, septate fungal hyphae and severe, predominantly neutrophilic inflammation. PCR of the cytology samples confirmed the presence of Aspergillus flavus while fungal and bacterial cultures were negative. Treatment with topical 1% voriconazole solution was successful in resolving the keratomycosis. 相似文献
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Carrie A. Davis Reza Seddighi Sherry K. Cox Xiaocun Sun Christine M. Egger Thomas J. Doherty 《Veterinary anaesthesia and analgesia》2017,44(4):727-737
Objective
To determine the effect of fentanyl on the induction dose of propofol and minimum infusion rate required to prevent movement in response to noxious stimulation (MIRNM) in dogs.Study design
Crossover experimental design.Animals
Six healthy, adult intact male Beagle dogs, mean ± standard deviation 12.6 ± 0.4 kg.Methods
Dogs were administered 0.9% saline (treatment P), fentanyl (5 μg kg?1) (treatment PLDF) or fentanyl (10 μg kg?1) (treatment PHDF) intravenously over 5 minutes. Five minutes later, anesthesia was induced with propofol (2 mg kg?1, followed by 1 mg kg?1 every 15 seconds to achieve intubation) and maintained for 90 minutes by constant rate infusions (CRIs) of propofol alone or with fentanyl: P, propofol (0.5 mg kg?1 minute?1); PLDF, propofol (0.35 mg kg?1 minute?1) and fentanyl (0.1 μg kg?1 minute?1); PHDF, propofol (0.3 mg kg?1 minute?1) and fentanyl (0.2 μg kg?1 minute?1). Propofol CRI was increased or decreased based on the response to stimulation (50 V, 50 Hz, 10 mA), with 20 minutes between adjustments. Data were analyzed using a mixed-model anova and presented as mean ± standard error.Results
ropofol induction doses were 6.16 ± 0.31, 3.67 ± 0.21 and 3.33 ± 0.42 mg kg?1 for P, PLDF and PHDF, respectively. Doses for PLDF and PHDF were significantly decreased from P (p < 0.05) but not different between treatments. Propofol MIRNM was 0.60 ± 0.04, 0.29 ± 0.02 and 0.22 ± 0.02 mg kg?1 minute?1 for P, PLDF and PHDF, respectively. MIRNM in PLDF and PHDF was significantly decreased from P. MIRNM in PLDF and PHDF were not different, but their respective percent decreases of 51 ± 3 and 63 ± 2% differed (p = 0.035).Conclusions and clinical relevance
Fentanyl, at the doses studied, caused statistically significant and clinically important decreases in the propofol induction dose and MIRNM. 相似文献40.