The structure of the upper atmosphere of mars: In situ accelerometer measurements from mars global surveyor

The Mars Global Surveyor (MGS) z-axis accelerometer has obtained over 200 vertical structures of thermospheric density, temperature, and pressure, ranging from 110 to 170 kilometers, compared to only three previous such vertical structures. In November 1997, a regional dust storm in the Southern Hemisphere triggered an unexpectedly large thermospheric response at mid-northern latitudes, increasing the altitude of thermospheric pressure surfaces there by as much as 8 kilometers and indicating a strong global thermospheric response to a regional dust storm. Throughout the MGS mission, thermospheric density bulges have been detected on opposite sides of the planet near 90 degreesE and 90 degreesW, in the vicinity of maximum terrain heights. This wave 2 pattern may be caused by topographically-forced planetary waves propagating up from the lower atmosphere.     

Comparison of tiletamine-zolazepam-ketamine and tiletamine-zolazepam-ketamine-xylazine anaesthesia in sheep

Summary The anaesthetic effects of intravenous tiletamine-zolazepam 6.6 mg/kg-ketamine 6.6 mg/kg (TK) and tiletamine-zolazepam 6.6 mg/kg-ketamine 6.6 mg/kg-xylazine 0.11 mg/kg (TKX) were evaluated in six wethers. Heart rate, respiration rate, arterial blood pressure, and the electrocardiogram were monitored during anaesthesia. Analgesia was tested by electrical stimulation in the left flank. Atropine (0.03 mg/kg) was given intramuscularly before induction, but after recording of baseline heart rate and respiratory rate. The duration of analgesia was 28.7 ± 6.9 min with TK and 82.8 ± 26.6 min with TKX. Heart rate increased significantly within 5 min after TK or TKX administration. Respiratory rate remained unchanged after TK administration, but increased significantly from 5 to 45 min after TKX administration. Arterial blood pressure decreased significantly at 15 min with TK and 30 min with TKX. Sheep remained recumbent for 201 min with TK and 166 min with TKX. All recovered uneventfully. We conclude that either TK or TKX may be used for anaesthetising sheep.     

Snake envenomation in cats and its detection by rapid immunoassay

Objective To determine the usefulness of a snake venom detection kit (SVDK) in the management of envenomed cats.
Design A clinical study.  

Animals

Twenty-two cats were investigated.
Procedure Cats injected subcutaneously with approximately 0.25 or 1.0 lethal dose (LD) of tiger snake venom or 1 or 4 LD of brown snake venom were observed for clinical symptoms of envenomation at intervals over the ensuring 24 to 48 hours(h). Blood and urine samples were taken at regular intervals and assayed in a quantitative laboratory assay for snake venoms. Selected samples were assayed in parallel in a rapid, semi-quantitative SVDK.
Results The studies showed that it was important to estimate the elapsed time from envenomation to presentation. If this time was less than 8 h, blood was the most appropriate sample and a negative result should exclude serious envenomation. If the elapsed time exceeded 8 h, it was essential that urine be sampled. Venom levels in urine were high at 8 h and approached the level of test sensitivity over 24 to 48 h; however by this time clinical signs were obvious in endangered cats.  

Conclusions

Careful use of the SVDK is a valuable aid in the management of a potentially envenomed cat.     

The immunophenotype of peripheral blood lymphocytes in clinically healthy dogs and dogs with lymphoma in remission

Lymphoma is a common cancer of dogs that frequently is treated with chemotherapy or radiation therapy. Response to therapy is variable and currently available diagnostic tests do not reliably predict response to therapy. Treatment for lymphoma often results in lymphopenia, but it is unknown whether the changes in circulating lymphocytes result from generalized or specific reduction of lymphocytes. In this study, blood lymphocytes from 12 clinically healthy dogs, 10 dogs in remission because of treatment for B-cell lymphoma, and 8 dogs in remission from T-cell lymphoma were analyzed by flow cytometry by using a panel of 20 antibodies reactive with canine leukocyte antigens. Results identified similar lymphocyte parameters in treated dogs regardless of the type of lymphoma. Treated dogs had >50% reduction in blood lymphocyte concentration, and an absolute decrease in most subsets of lymphocytes. Both groups of treated dogs had relative increases in the proportion of CD3+, T-cell receptor (TCR)αβ+, and CD90+ lymphocytes, and a decreased proportion of CD45RA+ cells. In addition, dogs with T-cell lymphoma in remission had a significant increase in the proportion of CD49d+ lymphocytes. These findings were interpreted as representing likely suppression of lymphocyte regeneration by chemotherapy, with a relative increase in the proportion of memory over naïve lymphocytes. Lack of correlation with the T- or B-cell origin of the initial lymphoma suggested that, by using flow cytometric methods, residual circulating neoplastic cells could not be detected. However, the changes in the lymphocyte profile of dogs treated with chemotherapy may have relevance to their immunocompetence.     

Plasma hormones and metabolites in cattle in relation to breed (Belgian Blue vs Holstein) and conformation (double-muscled vs dual-purpose type)

Four Belgian Blue double-muscled type (BBDM) bulls, four Belgian Blue dual-purpose type (BBDP) bulls and four Holstein bulls were used in a fattening trial in order to relate differences in the extent of muscle development and adiposity to differences in digestibility, endocrine status, protein and lipid metabolism. The larger muscle development in BBDM animals was associated with a trend to higher nitrogen retention, higher food conversion efficiency (p<0.05) and lower apparent digestibility (p<0.05). No difference was found between the groups for plasma glucose concentration. Higher creatinine, lower -amino nitrogen, lower triglycerides and higher non-esterified fatty acid plasma levels were observed in BBDM as compared to Holstein bulls (p<0.05), the BBDP group being intermediate. A trend to a higher cholesterol plasma level was found in BBDM animals. There was no difference between the three groups in plasma fatty acid composition, except for the C_14:0 content. Some of the differences in plasma metabolites were related to carcass composition and endocrine regulation, a decrease in muscle development and an increase in adiposity being associated with lower growth hormone production (p<0.05) and higher insulin (p<0.05) and IGF₁ secretions. The insulin/growth hormone ratio at the end of the fattening period was 0.0011, 0.0018 and 0.0069 in BBDM, BBDP and Holstein bulls, respectively, and was directly associated with fat deposition.Abbreviations BBDM Belgian Blue breed double-muscled type - BBDP Belgian Blue breed dual-purpose type - IGF₁ insulin-like growth factor 1 - NEFA non-esterified fatty acids - T₃ triiodothyronin - T₄ tetraiodothyronin     

Accounting for spatial autocorrelation improves the estimation of climate,physical environment and vegetation’s effects on boreal forest’s burn rates

Context

Wildfires play a crucial role in maintaining ecological and societal functions of North American boreal forests. Because of their contagious way of spreading, using statistical methods dealing with spatial autocorrelation has become a major challenge in fire studies analyzing how environmental factors affect their spatial variability.

Objectives

We aimed to demonstrate the performance of a spatially explicit method accounting for spatial autocorrelation in burn rates modelling, and to use this method to determine the relative contribution of climate, physical environment and vegetation to the spatial variability of burn rates between 1972 and 2015.

Methods

Using a 482,000 km² territory located in the coniferous boreal forest of eastern Canada, we built and compared burn rates models with and without accounting for spatial autocorrelation. The relative contribution of climate, physical environment and vegetation to the burn rates variability was identified with variance partitioning.

Results

Accounting for spatial autocorrelation improved the models’ performance by a factor of 1.5. Our method allowed the unadulterated extraction of the contribution of climate, physical environment and vegetation to the spatial variability of burn rates. This contribution was similar for the three groups of factors. The spatial autocorrelation extent was linked to the fire size distribution.

Conclusions

Accounting for spatial autocorrelation can highly improve models and avoids biased results and misinterpretation. Considering climate, physical environment and vegetation altogether is essential, especially when attempting to predict future area burned. In addition to the direct effect of climate, changes in vegetation could have important impacts on future burn rates.