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41.
Lacroux C Nguyen TH Andreoletti O Prevot F Grisez C Bergeaud JP Gruner L Brunel JC Francois D Dorchies P Jacquiet P 《Veterinary research》2006,37(4):607-622
Selection of resistant animals and host immunization have been proposed as alternative methods for the control of gastrointestinal nematode parasites. However, a better knowledge of the mechanisms involved in protective immunity against these parasites is required for the development of optimal strategies. In this study, 3 month old INRA 401 lambs (n = 81) were allocated into three groups: uninfected control, challenged either once (primary-infected animals) or twice (previously-infected animals) with 10,000 Haemonchus contortus L3. Uninfected control and challenged animals were sequentially sacrificed at 3, 7, 15 and 28 days post challenge. In both challenged groups, a clear Th2-oriented immune response was observed in the abomasal lymph node and mucosa. IL-4 and IL-13 mRNA over-expression, recruitment of eosinophils, mast cells and globule leukocytes and production of specific systemic IgG and mucosal IgA were observed earlier in previously-infected animals than in primary-infected ones. At 28 days post infection, no differences between intensities of these responses were observed between the challenged groups. Worm establishment rates were similar in previously-infected and primary-infected lambs. However, reductions of worm development, female fecundity and fecal egg output were observed in previously-infected sheep. We conclude that H. contortus infection in young INRA 401 lambs induced an unequivocal Th2 immune response resulting in the regulation of worm egg production without affecting their establishment. 相似文献
42.
Guyon F Douet C Colas S Salagoïty MH Medina B 《Journal of agricultural and food chemistry》2006,54(26):9918-9923
Despite the robustness of isotopic methods applied in the field of wine control, isotopic values can be slightly influenced by enological practices. For this reason, must concentration technique effects on wine isotopic parameters were studied. The two studied concentration techniques were reverse osmosis (RO) and high-vacuum evaporation (HVE). Samples (must and extracted water) have been collected in various French vineyards. Musts were microfermented at the laboratory, and isotope parameters were determined on the obtained wine. Deuterium and carbon-13 isotope ratios were studied on distilled ethanol by nuclear magnetic resonance (NMR) and isotope ratio mass spectrometry (IRMS), respectively. The oxygen-18 ratio was determined on extracted and wine water using IRMS apparatus. The study showed that the RO technique has a very low effect on isotopic parameters, indicating that this concentration technique does not create any isotopic fractionation, neither at sugar level nor at water level. The effect is notable for must submitted to HVE concentration: water evaporation leads to a modification of the oxygen-18 ratio of the must and, as a consequence, ethanol deuterium concentration is also modified. 相似文献
43.
Chetboul V Daste T Gouni V Concordet D Trehiou-Sechi E Serres F Pouchelon JL Germain CA Layssol-Lamour C Lefebvre HP 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2012,26(1):101-108
Background
Azotemia occurs frequently in dogs with degenerative mitral valve disease (DMVD). It could indicate changes in renal hemodynamics.Hypothesis/Objectives
To assess the renal resistive index (RI) in dogs with DMVD, and the statistical link between heart failure class, azotemia, echo‐Doppler parameters, several plasma variables, and RI.Animals
Fifty‐five dogs with naturally occurring DVMD were used (ISACHC class 1 [n = 28], 2 [n = 19], and 3 [n = 8]).Methods
Observational, blinded study, performed under standardized conditions. Physical examination, renal ultrasonography, and echo‐Doppler examinations were performed in awake dogs. The RI of the renal, interlobar, and arcuate arteries were measured. Plasma creatinine, urea, and N‐terminal pro‐B‐type natriuretic peptide concentrations (NT‐proBNP) were determined. Statistical links between variables and RI were tested by means of a general linear model.Results
Although the RI of renal and arcuate arteries were unaffected by ISACHC class, the left interlobar RI increased (P < .001) from 0.62 ± 0.05 (mean ± SD) in class 1 to 0.76 ± 0.08 in class 3. It was also higher (P < .001) in azotemic (0.74 ± 0.08) than in non‐azotemic (0.62 ± 0.05) dogs. Similar findings were observed for right interlobar RI. Univariate analysis showed a positive statistical link between NT‐proBNP (P = .002), urea (P < .001), creatinine (P = .002), urea‐to‐creatinine ratio (P < .001), left atrium‐to‐aorta ratio (P < .001), regurgitation fraction (P < .001), systolic pulmonary arterial pressure (P < .001), shortening fraction (P = .035), and RI.Conclusion and Clinical Importance
In dogs with DMVD, interlobar RI increases with heart failure severity and azotemia but a cause and effect relationship remains to be established. 相似文献44.
Jonathan N. King Mike Martin Valrie Chetboul Luca Ferasin Anne T. French Günther Strehlau Wolfgang Seewald Sarah G. W. Smith Simon T. Swift Susan L. Roberts Andrea M. Harvey Christopher J. L. Little Sarah M. A. Caney Kerry E. Simpson Andrew H. Sparkes Eleanor J. Mardell Eric Bomassi Claude Muller John P. Sauvage Armelle Diqulou Matthias A. Schneider Laurence J. Brown David D. Clarke Jean‐Francois Rousselot 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2019,33(6):2559-2571
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49.
Lesnoff M Laval G Bonnet P Chalvet-Monfray K Lancelot R Thiaucourt F 《Preventive veterinary medicine》2004,62(2):101-117
Contagious bovine pleuropneumonia (CBPP) is a respiratory disease of cattle; CBPP is caused by Mycoplasma mycoides subsp. mycoides small colony. CBPP is a major cause for concern for African countries (because of mortality, animal-production losses and cost of control). The clinical form of the disease is the more infectious (contagion occurs essentially through coughing). However, chronic lung lesions with viable mycoplasmas can persist in recovering cattle. Animals presenting these lesions might have a time-delimitated infectious phase. Such carriers are suspected to generate field outbreaks (although this hypothesis remains debated). We investigated the potential quantitative effects of these chronic carriers on the within-herd CBPP spread. Data were collected during a longitudinal field herd survey in a mixed crop-livestock system in the Ethiopian highlands. Two stochastic Markov-chain models' outputs (seroconversion dynamics, basic reproduction ratio R0, cumulative clinical incidence and risk of herd infection) were compared given different hypotheses on the carrier infectiousness. The late seroconversions observed in the field data were fitted correctly only for the highest carrier infectiousness we considered (mean chronic duration of 1 year and carriers 50-times less infectious than clinical cases). Although sensitivities (in terms of disease impact in the herd) were in general negligible when the carrier infectiousness was low (e.g. when carriers were assumed to be 1000-times less infectious than clinical cases), they rapidly became important when the infectiousness increased. 相似文献
50.
Effects of salinity on germination,growth and yield of cowpea 总被引:1,自引:0,他引:1
Summary Adequate information on salt tolerance is lacking for cowpea (Vigna unguiculata (L.) Walp.), a crop grown under both dryland and irrigated conditions. A two-year field plot study was conducted to determine the responses of both the vegetative and dry seed yield of cowpea to a range of soil salinities. Four salinity levels were imposed each year on a Pachappa fine sandy loam (mixed, thermic, Mollic Haploxeralf). Vegetative growth, dry seed yield, and several components of seed yield were measured.Vegetative yield was decreased more by increasing soil salinity than was dry seed yield. Vegetative growth was reduced 9.0% for each unit increase in electrical conductivity of the soil saturation extract beyond a threshold value of 1.6 dS/m. Dry seed yield was reduced 12% for each unit increase beyond 4.9 dS/m. Fewer pods per plant accounted for nearly all of the seed yield reduction associated with increasing salinity levels.Germination was significantly reduced when electrical conductivity in sand cultures exceeded 12.0 dS/m. 相似文献