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71.
Despite the potential of feline immunodeficiency virus (FIV) as an animal model for human immunodeficiency virus (HIV) studies, the long term effects of naturally-occurring infection have not been determined. HIV infection causes an ongoing deterioration in immune function which directly correlates with disease, in particular acquired immunodefciency syndrome (AIDS). However, it is not known whether FIV-induced immunosuppression is progressive or related to the clinical condition. This study examined changes in lymphocyte subset numbers of serial samples, taken from cohorts of FIV-positive and FIV-negative cats over an 18-month period. FIV-positive cats were clinically staged as asymptomatic carriers (AC) or cats with AIDS-related complex (ARC), and FIV-negative cats matched and staged on the basis of similar diseases. During the course of the study, 4 FIV-positive cats developed AIDS, classed as the terminal stage of infection. There were no significant differences in the mean absolute numbers of any lymphocyte subset between the onset (to) and the completion (t18) of the study. Similarly there were no significant changes in subset numbers during the 18 months preceding the development of AIDS. While the study period was brief and the sample sizes small, it is postulated that FIV infection in Australia may not necessarily cause progressive immunodeficiency and that FIV-induced immunosuppression (as measured by subset analysis) may not be well correlated with the clinical status of the infected cat. 相似文献
72.
Nasopharyngeal cryptococcosis 总被引:1,自引:0,他引:1
R MALIK P MARTIN DI WIGNEY DB CHURCH W BRADLEY CR BELLENGER WA LAMB VR BARRS S FOSTER S HEMSLEY PJ CANFIELD DN LOVE 《Australian veterinary journal》1997,75(7):483-488
Naturally occurring cryptococcosis in five cats, a dog and a koala is described. Involvement of the nasopharynx was documented in all patients, and nasopharyngeal mass lesions accounted for the major presenting complaints in four. Signs referable to nasopharyngeal disease included snoring, stertor, inspiratory dyspnoea and aerophagia. Diagnoses were made by caudal rhinoscopy using a retroverted flexible endoscope, vigorous orthograde flushing with saline, or at necropsy. Concurrent cryptococcal rhinitis was present in all cases, although involvement appeared limited to the caudal nasal cavity in most cases. Typical signs of nasal cavity disease, such as sneezing and nasal discharge, were often absent. Treatment of nasopharyngeal cryptococcosis should include physical dislodgement or debulking of lesion(s) to provide immediate alleviation of upper airway obstruction, followed by systemic antifungal therapy to eliminate residual infection from the nasal cavity. Infections caused by Cryptococcus neoformans var gattii accounted for a disproportionately large number of these cases. 相似文献
73.
PJ CANFIELD L. VOGELNEST ML CUNNINGHAM GS VISVESVARA 《Australian veterinary journal》1997,75(2):97-100
Objective
To describe a case of meningoencephalitis caused by Balamuthia mandrillaris in an orang utan.
Design
A pathological case report.
Animal
A 20 years old male orang utan (Pongo pygmaeus).
Procedure
The disease process was investigated by clinical pathology, necropsy, histopathology and immunofluorescence labelling.
Results
The orang utan developed sudden onset of depression, lethargy, inappetence and apparent head pain. The condition was considered to be related to a 2 year history of upper and lower respiratory disease, and the animal was placed on antibiotics after extensive testing. By the seventh day the animal had become ataxic and disoriented and a brain abscess was suspected. He died on the ninth day of illness. At necropsy, and subsequent sectioning, the brain showed multiple circular, soft, white to grey brown areas of varying size, the largest being in the left temporal (3.5 cm diameter) and right occipital (2.5 cm diameter) regions of the cerebrum. Histological examination of these regions revealed many amoebic trophozoites and occasional cysts associated with areas of haemorrhage and inflammatory necrosis. The trophozoites were packed in perivascular spaces and their nuclei often contained two or more prominent nucleoli. Immunofluorescent labelling of histological sections suggested that the agent was B mandrillaris.
Clinical implications
This report provides further evidence that B mandrillaris , a free living amoeba, can act as a pathogen in animals as well as people, and cause fatal meningoencephalitis. Along with Naegleria and Acanthamoeba spp, B mandrillaris should be considered amongst the causes of acute onset meningoencephalitis in animals. 相似文献
To describe a case of meningoencephalitis caused by Balamuthia mandrillaris in an orang utan.
Design
A pathological case report.
Animal
A 20 years old male orang utan (Pongo pygmaeus).
Procedure
The disease process was investigated by clinical pathology, necropsy, histopathology and immunofluorescence labelling.
Results
The orang utan developed sudden onset of depression, lethargy, inappetence and apparent head pain. The condition was considered to be related to a 2 year history of upper and lower respiratory disease, and the animal was placed on antibiotics after extensive testing. By the seventh day the animal had become ataxic and disoriented and a brain abscess was suspected. He died on the ninth day of illness. At necropsy, and subsequent sectioning, the brain showed multiple circular, soft, white to grey brown areas of varying size, the largest being in the left temporal (3.5 cm diameter) and right occipital (2.5 cm diameter) regions of the cerebrum. Histological examination of these regions revealed many amoebic trophozoites and occasional cysts associated with areas of haemorrhage and inflammatory necrosis. The trophozoites were packed in perivascular spaces and their nuclei often contained two or more prominent nucleoli. Immunofluorescent labelling of histological sections suggested that the agent was B mandrillaris.
Clinical implications
This report provides further evidence that B mandrillaris , a free living amoeba, can act as a pathogen in animals as well as people, and cause fatal meningoencephalitis. Along with Naegleria and Acanthamoeba spp, B mandrillaris should be considered amongst the causes of acute onset meningoencephalitis in animals. 相似文献
74.
75.
Cattle in two herds developed signs of bloating, increased salivation and lacrimation, depression, respiratory distress, ataxia, and death after ingestion of hay that contained large amounts of poison hemlock (Conium maculatum). Twenty of 30 Angus cows and calves were affected in the first herd (2 died). In the second herd, 5 of 30 Holstein heifers were affected (1 died). The Conium alkaloids, coniine and gamma-coniceine, were quantified in the hay, the plants from the responsible hayfield, and the urine of affected animals. 相似文献
76.
The authors investigate counter-urbanization and population change in Georgia between 1960 and 1980 by examining commuting patterns. "The immediate objective is to construct the entire set of commuting fields of both large metropolitan areas to metropolitan and nonmetropolitan employment centers. We then proceed to the relationship between commuting from nonmetropolitan areas to all levels of Georgia's urban hierarchy and population change in these nonmetropolitan settings. By matching population growth and decline areas with explicit employment ties...the nature of the population changes is much better understood." Data from the 1960, 1970, and 1980 censuses for 581 Census County Divisions (CCDs) in Georgia are analyzed. It is concluded that "most nonmetropolitan growth taking place in Georgia is associated with intensification of metropolitan commuting fields along with growth of nonmetropolitan centers and their influence along the very periphery of metropolitan spheres of employment influence. However, a significant share of Georgia's nonmetropolitan population revitalization is explained by growth independent of direct metropolitan influence. It would appear then that nonmetropolitan growth centers are an important part of the basis for population decentralization in Georgia. Metropolitan spill-over alone cannot account for counterurbanization on this portion of the American economic landscape." 相似文献
77.
78.
79.
P.F. Fisher 《Geoderma》1983,29(2):93-105
The properties of soils associated with the Bronze Age site near the South Lodge of Rushmore Park, Wiltshire, are described. Three primary soil types are identified: rendzinas (Rendolls), argillic brown earths (Hapludalfs) and a brown calcareous earth (Eutrochrept). The mapped distribution of these soil types is related to the archaeological landscape. The argillic brown earths are limited in extent to the deeper soils of the positive (accumulating) lynchets of the field system, whereas rendzinas occupy the negative (eroding) lynchets and the remainder of the fields. The only occurrence of a brown calcareous earth is in a positive lynchet within the enclosure. From the distribution of soil types and analogies with the soils of other prehistoric field systems on the Chalk, it is concluded that the argillic brown earths have formed from a highly calcareous colluvial deposit since abandonment of the field system in the later Bronze Age. Further, the development of this soil type appears to be controlled by lateral throughflow of soil water combined with the re-establishment of a wooded landscape. Formation of the argillic brown earth at this site appears to be more recent than at any other site in southern England for which information has been published. 相似文献
80.