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991.
Reed AL Keller GG Vogt DW Ellersieck MR Corley EA 《Journal of the American Veterinary Medical Association》2000,217(5):675-680
OBJECTIVE: To determine in dogs what effect using hip conformation scores assigned by the Orthopedic Foundation for Animals (OFA) as a criterion for breeding selections would have on hip conformation scores of the progeny. DESIGN: Longitudinal study. ANIMALS: English Setters, Portuguese Water Dogs, Chinese Shar-peis, and Bernese Mountain Dogs for which OFA hip conformation scores were known. PROCEDURE: Pedigree data were obtained from the national breed clubs and the American Kennel Club and merged with data from the OFA hip conformation score database. An ANOVA was used to evaluate the effects of sex, age at the time of radiographic evaluation, and year of birth on the variation in hip conformation scores among the progeny. Heritability was estimated by use of within-year midparent offspring regression analyses. RESULTS: Significant differences in progeny hip conformation scores between sexes were not detected, but age at the time of radiographic evaluation and year of birth had a significant effect on hip joint conformation of the progeny. Estimated heritability (mean +/- SE) was 0.26 +/- 0.03, and dam and sire hip conformation scores had a significant effect on progeny hip conformation scores. Annual decreases in percentage of dysplastic progeny and increases in percentages of progeny and breeding dogs with phenotypically normal hip joint conformation were detected. CONCLUSIONS AND CLINICAL RELEVANCE: Results indicated that hip conformation scores have moderate heritability in dogs and selection of breeding stock with better hip conformation scores will increase the percentage of progeny with phenotypically normal hip joint conformation. 相似文献
992.
993.
994.
Studies on vitamin E and selenium deficiency in young pigs. III. Effect on kinetics of erythrocyte production and destruction. 下载免费PDF全文
The effect of vitamin E and/or selenium deficiency on the kinetics of erythrocyte production and destruction has been investigated in swine. The plasma iron turnover rate, 59Fe incorporation into newly formed red cells as well as the 51Cr apparent red cell half-life, were not found to be significantly affected by either vitamin E deficiency, selenium deficiency or deficiency of both, as compared to replete animals. The results of this study suggest that vitamin E is not a limiting factor for normal erythropoiesis in young growing pigs. Erythropoiesis appeared, however, to be slightly decreased in selenium deficient pigs and will need to be further investigated. 相似文献
995.
Michael S. Stone Ian B. Johnstone Marjory Brooks Trent K. Bollinger Susan M. Cotter 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1994,8(1):57-61
A circulating anticoagulant was detected in a 2-year-old Chesapeake Bay Retriever with hemolytic anemia, nephrotic syndrome, thrombocytopenia, polyarthropathy, and pulmonary thromboembolism. A persistent prolongation of the activated partial thromboplastin time (aPTT) was detected, and it did not correct with repeated administration of fresh frozen plasma. The aPTT was still prolonged, with a 1:1 mixture of patient's plasma and normal dog plasma in vitro, suggesting the presence of a circulating inhibitor. Results of assays to characterize the inhibitor were compatible with those described for the lupus anticoagulant in human patients with systemic lupus erythematosus. Paradoxically, patients having the lupus anticoagulant are at increased risk for thrombosis. Pulmonary thromboembolism has been described as a frequent complication of immune-mediated hemolytic anemia in the dog, and the presence of a circulating anticoagulant should be considered as a potential mechanism. 相似文献
996.
Bobwhite quails (Colinus virginianus) were inoculated with 10(6) mean tissue-culture infective dose of quail bronchitis virus at 1, 3, 6, or 9 weeks of age by intratracheal, intraperitoneal, or subcutaneous routes. Quails developed necrotizing tracheitis, proliferative and necrotizing bronchitis and pneumonia; multifocal necrotizing hepatitis; necrotizing splenitis, with or without hyperplasia of splenic mononuclear phagocytes; bursal lymphoid necrosis; and bursal atrophy. Lesions were more extensive and severe in quails inoculated at 1 or 3 weeks of age than in older quails. Large intranuclear inclusions, characteristic of adenovirus infection, were identified in trachea, lung, liver, and bursa of Fabricius. This is the first report of the histopathology of experimentally induced quail bronchitis. 相似文献
997.
998.
M A Albassam B J Houston P Greaves N Barsoum 《Journal of the American Veterinary Medical Association》1989,194(11):1595-1597
A 13-month-old Beagle became anorectic and had fever, stiff gait, and tenderness in the inguinal region. Clinical signs of disease were associated with neutrophilia and a decrease in the albumin-to-globulin ratio. The dog became clinically normal for 5 days after 3 days of treatment with penicillin G and dihydrostreptomycin. Clinical signs of disease recurred, and the dog was euthanatized after failing to respond to administration of a trimethoprim-sulfamethoxazole combination for 9 days. Disseminated arteritis was seen in the testes, epididymides, mesentery, coronary arteries, aorta, and thyroid gland. Lesions were seen in large and medium-sized arteries and varied from acute necrotizing arteries to a chronic lesion with organization and recanalization of thrombi. The clinical signs of disease resembled those of Beagle pain syndrome, described in laboratory Beagles. 相似文献
999.
Field studies were conducted at Alupe in western Kenya in 1995 and 1996 to evaluate the efficacy of crop and species mixtures for the management of sorghum anthracnose (caused by Colletotrichum sublineolum) and leaf blight (caused by Exserohilum turcicum). The progress of these diseases developing simultaneously on a susceptible sorghum cultivar planted in inter- or intra-row mixtures of varying proportions with either maize or resistant sorghum was monitored. The effects of host type and mixture patterns on disease progress were compared by parameter estimates derived from fitted Lotka-Volterra competition equations and nonlinear logistic models. Competition coefficients were not significant and their confidence intervals included zero in most cases, suggesting that interactions between C. sublineolum and E. turcicum did not occur. Mixtures of the susceptible sorghum with either the nonhost maize or the resistant sorghum delayed the time when disease is first observed and reduced the rate of disease progress and carrying capacity for both anthracnose and leaf blight, with a more pronounced effect on the latter disease. The lower efficacy of mixtures in reducing anthracnose was attributed to an aggregated spatial pattern, coupled with higher rates of progress for this disease. Intra-row mixtures were more efficient than inter-row mixtures in reducing disease development in all years. The implications of these observations for the management of sorghum diseases under small-scale farming systems are discussed. 相似文献
1000.
Summary Studies of the effects of different forms of N on urease production in soils amended with organic C showed that although microbial activity, as measured by CO2 production, was stimulated by the addition of NH4
+ or NO3
- to C-amended soils (200 mol glucose-C g–1 soil), urease production was repressed by these forms of N. The addition of L-methionine sulfoximine, an inhibitor of inorganic N assimilation by microorganisms, relieved the NH4
+ and NO3
- repression of urease production in C-amended soil. The addition of sodium chlorate, an inhibitor of NO3
- reduction to NH4
+ by microorganisms, relieved the NO3
- repression of urease production, but did not eliminate the repression associated with NH4
+. These observations indicate that microbial production of urease in C-amended soils is not directly repressed by NH4
+ or NO3
-, but by products formed by microbial assimilation of these forms of N. This conclusion is supported by our finding that the biologically active L-isomers of alanine, arginine, asparagine, aspartate, and glutamine, repressed urease production in C-amended soil, whereas the D-isomers of these amino acids had little or no influence on urease production. This work suggests that urease synthesis by soil microorganisms is controlled by the global N regulon. 相似文献