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M. Ryan Smith DVM DACVECC Virginie A. Wurlod MS Dr vet med DACVECC DECVECC Chin-Chi Liu MS MApStat PhD 《Journal of Veterinary Emergency and Critical Care》2023,33(6):648-655
Objective
To describe hemostatic derangements associated with canine anaphylaxis and to assess for association with syndrome severity.Design
Prospective observational study.Setting
University teaching hospital.Animals
Twenty-seven client-owned dogs, recruited from November 2018 to January 2022, diagnosed with anaphylaxis of varying severity were included. Study inclusion required presentation <6 hours after initiation of clinical signs, no medications or history of illness within the prior 2 weeks, lack of comorbidities expected to affect hemostasis, and lack of a disease state that could alternatively explain the clinical presentation.Interventions
Blood samples were collected within the first hour of presentation for CBC, serum biochemistry, prothrombin time (PT), activated partial thromboplastin time (aPTT), and viscoelastic coagulation testing for use with a cartridge-based point-of-care device.Measurements and main results
Clotting time and clot formation time were prolonged, alpha angle and maximum clot firmness were decreased, PT and aPTT were prolonged, and platelet counts were lower in severe cases compared to mild and moderate cases. There were no differences for any parameter between mild and moderate cases. The presence or absence of abdominal effusion was not associated with hemostatic status.Conclusions
Global hemostatic derangements consistent with hypocoagulability are a prominent feature of severe anaphylaxis in dogs and should be considered for routine evaluation. 相似文献105.
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Finnegan Laura Viejou Rebecca MacNearney Doug Pigeon Karine E. Stenhouse Gordon B. 《Landscape Ecology》2021,36(9):2619-2635
Landscape Ecology - Anthropogenic disturbance alters animal movements. Large mammals require vast areas to meet their needs, and they encounter anthropogenic disturbances frequently during daily... 相似文献
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C. F. E. Topp G. Hughes I. M. Nevison A. Butler S. J. P. Oxley N. D. Havis 《Plant pathology》2019,68(6):1179-1187
A programme of field trials for the study of the winter barley–Rhynchosporium commune pathosystem is reported. The associated seedborne disease rhynchosporium leaf scald is regarded as having an important impact on barley yields. The analysis in this study relates to the impact of the seed source (commercial or farm-saved seed) on disease incidence and to the spatial pattern of rhynchosporium leaf scald disease incidence. Disease incidence data were calculated from field data recorded as disease severity. Mean disease incidence was higher in the crops grown from farm-saved seed than in those grown from commercial seed, although great agronomic significance cannot be attached to this result. The spatial pattern of rhynchosporium leaf scald disease incidence was characterized in terms of the binary power law (BPL) and was indicative of an aggregated pattern. Programme-wide BPL results were described using a novel phytopathological application of a random coefficients model. These results have application in field sampling for rhynchosporium leaf scald disease. 相似文献