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171.
Hypernatremia in Calves 总被引:2,自引:0,他引:2
John K. Pringle DVM DVSc Linda M. M. Berthiaume DVM 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1988,2(2):66-70
Hypernatremia (sodium chloride intoxication) is described in two calves due to presumed mixing errors of oral electrolyte solutions while undergoing therapy for neonatal diarrhea. The experimental induction of hypernatremia in two clinically normal calves is also reported. Physical findings in diarrheic calves included depression, weakness, dehydration, and diarrhea. Serum sodium concentrations were found to be 171.6 mEq/l and 208.0 mEq/l, respectively. Treatment with intravenous fluids was attempted in both cases, but one calf died after 6 hours and the other calf died after 2 days and exhibited periodic convulsions before death. Experimental induction with oral administration of 1 l of electrolyte concentrate, which contained approximately 2750 mEq sodium revealed that the normal calves would willingly consume the solution as mixed with milk and develop clinical signs of hypernatremia within 6 hours of administration. Serum sodium concentrations of 176.0 and 179.8 were found in the experimental calves and coincided with the onset of overt depression and weakness, at which time they were euthanatized. Cerebrospinal fluid electrolyte analysis paralleled the serum electrolyte alterations. 相似文献
172.
Elizabeth J. Laing DVM DVSc Peter J. Fitzpatrick MB BS FRCP FRCR AIlen G. Binnington DVM MSc AIan M. Norris DVM AIlen Mosseri MSc Walter D. Rider MB FRCP FRCP V. E. Valli DVM PhD Angela Baur BVSc 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1989,3(2):102-108
In a Phase I-II study, half-body radiotherapy was used to treat 14 dogs with multicentric lymphoma. Using this technique, a radiation dose of 7 Gray (Gy) was delivered to one half of the body in a single exposure. The other half of the body was treated approximately 28 days later. Of 14 treated dogs, 11 (79%) had a measurable decrease in tumor size. Five dogs achieved a complete or partial remission with a mean duration of 102 and 54 days, respectively. In predicting response to therapy, poor prognostic factors included large tumor burdens, advanced disease stage, and chemotherapy-resistant tumors. Side effects of treatment were divided chronologically into acute (radiation sickness, tumor lysis), subacute (bone marrow suppression), and chronic (radiation pneumonitis, lymphoma-cell leukemia) syndromes. Complications were more severe in tumor-bearing dogs when compared with healthy control animals. Dogs with small tumor burdens and minimal internal disease had fewer complications compared with those with more advanced disease. 相似文献
173.
Kate Hopper BVSc DACVECC Shane Bateman DVM DVSc DACVECC 《Journal of Veterinary Emergency and Critical Care》2005,15(2):83-91
Objective: To review the current understanding of mechanisms involved in normal hemostasis and to describe the changes associated with pro‐inflammatory disease processes such as sepsis. Data sources: Original research articles and scientific reviews. Human data synthesis: Organ damage caused by sepsis is created in part by the interdependent relationship between hemostasis and inflammation. Markers of coagulation have been found to have prognostic value in human patients with sepsis and there are both experimental and clinical investigations of the therapeutic potential of modulating the hemostatic system in sepsis. Improvement of 28‐day all‐cause mortality in severe sepsis by treatment with recombinant human activated Protein C strongly supports the interdependence of hemostasis and inflammation in the pathophysiology of sepsis. Veterinary data synthesis: Publications reporting clinical evaluation of the hemostatic changes occurring in septic dogs or cats are minimal. Experimental animal models of sepsis reveal significant similarity between human and animal sepsis and may provide relevance to clinical veterinary medicine until prospective clinical evaluations are published. Conclusions: It is now apparent that inflammation and the coagulation system are intimately connected. Understanding this relationship provides some insight into the pathogenesis of the hemostatic changes associated with sepsis. This new updated view of hemostasis may lead to the development of novel therapeutic approaches to sepsis and disseminated intravascular coagulation in veterinary medicine. 相似文献
174.
The use of 25% human serum albumin: outcome and efficacy in raising serum albumin and systemic blood pressure in critically ill dogs and cats 总被引:1,自引:0,他引:1
Karol A. Mathews DVM DVSc DACVECC Maureen Barry DVM DVSc DACVIM 《Journal of Veterinary Emergency and Critical Care》2005,15(2):110-118
Objective: To report on the use of 25% human serum albumin (25% HSA) (Plasbumin®), associated outcome, and efficacy in raising serum albumin and systemic blood pressure (BP) in critically ill dogs and cats. Design: Retrospective clinical study. Animals: Client‐owned cats and dogs. Interventions: Administration of 25% HSA. Measurements and main results: The medical records of 66 animals (64 dogs, 2 cats) at the Ontario Veterinary College, which received 25% HSA (Plasbumin®) from June 1997 to December 2001 were reviewed for age, body weight, clinical problems, albumin and globulin (g/L) levels pre‐ and within 18‐hour post‐transfusion and upon discharge from hospital, total solids (TS), systolic and diastolic BP pre‐ and post‐transfusion total volume administered, adverse reactions, blood products and synthetic colloids used, and outcome. Twenty‐five percent HSA was prescribed for a range of clinical problems, which were grouped into 6 categories for analysis. The age range was 4 months–12 years and body weight range 1.4–65 kg. The maximum volume administered to any dog was 25 mL/kg, mean volume administered was 5 mL/kg, maximum volume given as a slow push or bolus was 4 mL/kg with a mean of 2 mL/kg volume. The range for a constant rate infusion (CRI) was 0.1–1.7 mL/kg/hr over 4–72 hours. Forty‐seven (71%) animals survived to discharge; 11(16%) were euthanized, and 8 (12%) died. Serum albumin and TS increased significantly (P<0.0001) above pre‐transfusion levels as did systolic BP (P<0.01). Conclusions: Twenty‐five percent HSA can be safely administered to critically ill animals, and an increase in albumin levels and systemic BP can be expected. 相似文献
175.
Primary appendicular hemangiosarcoma and telangiectatic osteosarcoma in 70 dogs: A Veterinary Society of Surgical Oncology retrospective study 下载免费PDF全文
Michelle A. Giuffrida VMD MSCE DACVS Debra A. Kamstock DVM PhD DACVP Laura E. Selmic BVetMed MPH DACVS William Pass DVM Anna Szivek DVM DACVIM Michael B. Mison DVM DACVS Sarah E. Boston DVM DVSc DACVS Leslie E. Fox DVM MS DACVIM Cecilia Robat DrMedVet DACVIM Janet A. Grimes DVM MS DACVS Karl C. Maritato DVM DACVS Nicholas J. Bacon MA VetMB DECVS DACVS 《Veterinary surgery : VS》2018,47(6):774-783
176.
Galina M. Hayes PhD Deborah Reynolds BVSc Diplomate ACVS Noel M.M. Moens MS Diplomate ACVS & ECVS Ameet Singh DVM DVSc Diplomate ACVS Michelle Oblak DVM DVSc Diplomate ACVS Thomas W.G. Gibson DVM DVSc Diplomate ACVS Brigitte A. Brisson DVM DVSc Diplomate ACVS Alim Nazarali BSc Cate Dewey PhD 《Veterinary surgery : VS》2014,43(4):400-404
177.
Toby J. Koenig BVSc Andrew J. Dart BVSc PhD Diplomate ACVS & ECVS Neil Horadagoda BVSc PhD Robin J. Bell BVSc MVSc Diplomate ECVS Nigel Perkins BVSc PhD Diplomate ACT Christina Dart Dr. Med. Vet. DVSc MVSc Mark Krockenberger BVSc PhD Leo B. Jeffcott BVetMedPhD DVSc Christopher B. Little BVSc PhD Diplomate ACVS 《Veterinary surgery : VS》2014,43(5):612-622
178.
179.
LEE C. BURSTINER DVM MEREDITH FAIRES DVM MSc J. SCOTT WEESE DVM DVSc Diplomate ACVIM 《Veterinary surgery : VS》2010,39(2):150-157
Objective— To evaluate the prevalence of, and risk factors for, methicillin‐resistant Staphylococcus aureus (MRSA) colonization in veterinary personnel. Study Design— Cross‐sectional study. Sample Population— Conference attendees (n=341) at the 2008 American College of Veterinary Surgeons Symposium in San Diego California. Methods— Nasal swabs were collected and tested using selective culture for MRSA. Isolates were typed and risk factors were evaluated using questionnaire data. Results— 17.3% of subjects (17% veterinarians and 18% technicians) were MRSA positive. Colonized individuals originated from 5 different countries, predominantly the United States and Canada. Contact with small ruminants in the preceding 30 days (odds ratio [OR] 2.2), living with a person diagnosed with MRSA in the preceding year (OR 19.8) and working in a clinic where there is a specific person in charge of the infection control program (OR 2.2) were associated with colonization using multivariable analysis. Conclusion— The high rate of colonization identified here provides more evidence that MRSA exposure is likely an occupational risk for veterinary personnel. The equal rates in small animal and large animal personnel were surprising and contradict earlier studies indicating greater rates among equine personnel. The association of MRSA and small ruminant contact has not been reported previously. Clinical Relevance— MRSA is an important emerging pathogen in veterinary medicine and is a concern for both patients and veterinary personnel. The high colonization rate indicates the need to understand and control the spread of MRSA in veterinary clinics. 相似文献