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101.
K A Gossett D D French B Cleghorn G E Church 《American journal of veterinary research》1990,51(9):1370-1374
Hypertonic NaHCO3 infusion caused blood volume expansion, increased blood bicarbonate concentration, and delayed the onset of hypophosphatemia in ponies with endotoxemia. However, NaHCO3 infusion did not normalize blood pH, and it increased blood L-lactate concentration, and caused hypokalemia, hypernatremia, and hyperosmolality. The deleterious effects of NaHCO3 infusion in endotoxemia ponies outweighed the beneficial effects. The role of hypertonic NaHCO3 given IV for treatment of endotoxemia in equids must be reevaluated. 相似文献
102.
A E Peaston D B Church G S Allen S Haigh 《Journal of the American Veterinary Medical Association》1990,197(10):1354-1356
A dog was examined because of anorexia and development of submandibular, sternal, and forelimb edema. Physical examination revealed engorged jugular veins and engorged blood vessels of the conjunctivae and nictitating membranes. Thoracic radiography revealed pleural and pericardial effusions, later identified as chyle. Contrast angiography revealed an intravascular mass, later identified as thymoma, in the cranial vena cava. 相似文献
103.
Hematologic, biochemical, blood-gas, and acid-base values in greyhounds before and after exercise 总被引:1,自引:0,他引:1
After racing 722 m, 16 Greyhounds were evaluated to determine changes in hematologic, biochemical, blood-gas, and acid-base values following exercise. Values were determined before racing (T0), immediately after racing (T1), and 3 hours after racing (T2). Significant changes detected immediately after racing included increased heart rate, respiratory rate, and rectal temperature. Significant changes in hematologic values included increases in PCV, total plasma protein, hemoglobin, RBC, WBC, neutrophils, and lymphocytes. Change was not detected in values for monocytes, eosinophils, and neutrophil/lymphocyte ratio. Other increases included those for plasma concentrations of sodium, chloride, calcium, lactic acid, aspartate transaminase, alanine transaminase, alkaline phosphatase, creatine kinase, lactate dehydrogenase, and glucose. Concentrations of potassium and urea did not change. Measurement of blood-gas and acid-base status revealed significant increases in PaO2 and base deficit, whereas PaCO2, pH, and bicarbonate decreased. Three hours after exercise, all vital signs and blood-gas and acid-base values, except for PaCO2, which was still slightly low, had returned to baseline (T0) values. Most biochemical values had also returned to baseline, although sodium, chloride, aspartate transaminase, and creatine kinase were still high, and urea was low. Many hematologic values were still different from baseline values, with high values for WBC, neutrophils and neutrophil/lymphocyte ratio, and low values for PCV, total plasma protein, hemoglobin, RBC, and lymphocytes. 相似文献
104.
Blood L lactate concentration and anion gap were measured in 32 horses suspected of having metabolic acidosis. There was good linear correlation between these variables (r = 0.90791, P less than 0.0001) and both were good prognostic indicators. Anion gap was a good indicator of the presence but not the severity of L lactic acidosis and was a slightly better prognostic indicator. The ability to predict survival was not improved by the measurement of L lactate in addition to anion gap. 相似文献
105.
SUMMARY A combination of tiletamine hydrochloride and zolazepam hydrochloride in a 1:1 ratio by weight was used successfully to sedate mountain brushtail possums, Trichosurus caninus, in the field. A standard total dose of 50 to 60 mg provided adequate sedation for the completion of a range of handling procedures. We describe the induction time, dose rate and side-effects associated with the use of tiletamine and zolazepam in T caninus. 相似文献
106.
SUMMARY Responses (473) were collated from a questionnaire sent to 5054 veterinarians in Australia enquiring about drug preferences for treating cardiac disease in dogs and cats. When treating a small breed dog with endocardiosis and mild left congestive heart failure, 74% of 472 respondents used a diuretic, 67% a theophylline derivative, 27% a vasodilator and 20% a positive inotrope. Frusemide was the preferred diuretic and digoxin the preferred inotrope, but vasodilator use varied. Low sodium diets were “often recommended” by 71% of respondents. Propranolol was preferred to diltiazem for treating feline hypertrophic cardiomyopathy. Digoxin was clearly preferred for treating supraventricular dysrhythmias, while lignocaine and digoxin were preferred equally for ventricular dysrhythmias. Respondents appeared more willing than US veterinarians to use theophylline derivatives and prasozin, and less inclined to employ nitrates, hydralazine, inotropes other than digoxin, and low sodium diets. 相似文献
107.
108.
Shendure J Porreca GJ Reppas NB Lin X McCutcheon JP Rosenbaum AM Wang MD Zhang K Mitra RD Church GM 《Science (New York, N.Y.)》2005,309(5741):1728-1732
We describe a DNA sequencing technology in which a commonly available, inexpensive epifluorescence microscope is converted to rapid nonelectrophoretic DNA sequencing automation. We apply this technology to resequence an evolved strain of Escherichia coli at less than one error per million consensus bases. A cell-free, mate-paired library provided single DNA molecules that were amplified in parallel to 1-micrometer beads by emulsion polymerase chain reaction. Millions of beads were immobilized in a polyacrylamide gel and subjected to automated cycles of sequencing by ligation and four-color imaging. Cost per base was roughly one-ninth as much as that of conventional sequencing. Our protocols were implemented with off-the-shelf instrumentation and reagents. 相似文献
109.
A 14-year-old neutered female cat was presented for the investigation of aggression and male-type behaviour. Bilateral adrenal enlargement together with elevated plasma concentrations of oestradiol and testosterone were identified, with no evidence of hypercortisolaemia. These findings are similar to the syndrome of hyperadrenocorticism recognised most commonly in ferrets. The cat was treated for six months with the enzyme inhibitor drug, trilostane, and showed a moderate improvement in clinical signs. 相似文献
110.