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Kunkle GA Nicklin CF Sullivan-Tamboe DL 《Journal of the American Animal Hospital Association》2004,40(1):42-46
The purpose of this study was to determine if the temperatures obtained using a veterinary infrared (IR) thermometer agreed with a digital rectal thermometer in a group of research cats, half of which had transient fevers. The thermometers were weakly correlated (r=0.62). The mean difference was 0.13 degrees F (0.07 degrees C), and the limits of agreement were 2.6 degrees F (1.43 degrees C) and -2.5 degrees F (-1.36 degrees C), which were unacceptable for clinical purposes. The results of this study indicate that, while the IR thermometer was easy to use, it cannot be used interchangeably with the rectal thermometer. 相似文献
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Rosales MS Marsella R Kunkle G Harris BL Nicklin CF Lopez J 《Veterinary dermatology》2005,16(3):171-176
The purpose of this randomized, single blinded clinical trial was to evaluate cytologically and clinically the efficacy of oral cephalexin alone and its combination with terbinafine or ketoconazole for the treatment of Malassezia dermatitis in dogs. Twenty-two client-owned dogs with Malassezia dermatitis completed the 3-week study. All received cephalexin (generic, 250 mg or 500 mg) at 22-30 mg kg(-1) twice daily. Eight dogs received terbinafine at 30 mg kg(-1) once daily and seven dogs received ketoconazole (generic, 200 mg) at 5-10 mg kg(-1) twice daily. The remaining seven dogs received cephalexin alone. At week 0 (visit 1) and week 3 (visit 2), mean yeast counts were determined from three affected areas using tape-strip cytology, a clinical index score (CIS) was assigned to the affected areas, and owners evaluated pruritus using a visual analogue scale. All groups showed reduction in mean yeast counts, CIS and pruritus. There was an 86.8%, 80.2% and 28.8% reduction in mean yeast counts from visit 1 to visit 2 for the terbinafine, ketoconazole and cephalexin-only groups, respectively. However, within treatment group comparisons a significant reduction in mean yeast count was only evident for the terbinafine (P < 0.002) and ketoconazole (P < 0.01) groups. Pruritus reduction was only significant for the terbinafine group. These preliminary results suggest that terbinafine should be further assessed for the treatment of canine Malassezia dermatitis. 相似文献
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Holden C 《Science (New York, N.Y.)》2004,305(5687):1093
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