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101.
102.
Over a 6-year period seven adult horses of different breeds and genders developed multifocal, exudative, oozing dermatitis characterized histologically by epidermal spongiotic vesicles and perivascular eosinophilic, neutrophilic and mixed mononuclear inflammation. Three horses were pruritic. Systemic disease was not noted. Two horses had a history of recurrent urticaria (hives) and one horse had nodules or welt-type lesions that progressed to exudative, oozing lesions. Interepithelial immunoglobulin (Ig)G was detected by avidin-biotin complex-peroxidase staining, but the pattern of staining was more consistent with epithelial oedema than specific IgG deposition associated with pemphigus. The exudative oozing lesions developed under circumstances suggesting that dermal oedema progressed to intracellular and intercellular epidermal oedema, which in turn progressed to the spongiotic vesicular epidermal lesions. 相似文献
103.
Jane Oakey Judy Forbes-Faulkner Christopher Gilpin Bronwyn Murdoch Steven Johnson 《Journal of veterinary diagnostic investigation》2005,17(4):378-382
In 2003, a steer carcass was condemned at a Central Queensland abattoir because of metastatic tumors. In addition, a granulomatous lesion was found in the mediastinal lymph node. Histological examination showed this to be a pyogranuloma, typically associated with Rhodococcus or the Nocardia/Streptomyces group. However, in this case, the only etiological agent was an acid-fast bacillus, which would normally be associated with a more fibrous lesion. A number of nucleic acid-based techniques were used, and the isolate was identified as Mycobacterium asiaticum. This organism is a rarely encountered opportunistic pathogen of humans, associated with subtropical climates. This is the first report of this organism causing infection in cattle. The similarities between this case and cases of human disease are discussed. 相似文献
104.
To compare fluid-attenuated inversion recovery (FLAIR) and T2-weighted magnetic resonance (MR) imaging in small animal patients with suspected brain disease, paired sets of FLAIR and T2-weighted MR images of 116 dogs and cats were reviewed separately without any patient information. Images were rated as normal or abnormal using a five-point scale, and the distribution, signal intensity, and anatomic location of abnormalities were recorded. In 60 animals, both FLAIR and T2-weighted images were normal. In 50 animals, the same abnormalities were identified in both FLAIR and T2-weighted images. Overall, very good agreement was found between FLAIR and T2-weighted MR images (kappa = 0.88). FLAIR images had abnormalities that were not recognized in the corresponding T2-weighted images in six of 116 examinations (5%). In four of these, the abnormalities in FLAIR images were thought to represent pathology, including granulomatous meningoencephalitis in one dog, postictal edema in one dog, and undiagnosed lesions in two dogs. In the remaining two examinations, the abnormalities in FLAIR images were probably artifacts. No examples were found of intracranial abnormalities in T2-weighted images that were not visible in FLAIR images. In this study, acquiring FLAIR images in addition to T2-weighted images resulted in detection of otherwise occult abnormalities in relatively few patients. 相似文献
105.
Giunio Bruto Cherubini Panagiotis Mantis Teresa A. Martinez Christopher R. Lamb Rodolfo Cappello 《Veterinary radiology & ultrasound》2005,46(5):384-387
The aim of this study was to identify magnetic resonance (MR) signs that aid differentiation of neoplastic vs. non-neoplastic brain diseases in dogs and cats. MR images of 36 dogs and 13 cats with histologic diagnosis of intracranial disease were reviewed retrospectively. Diagnoses included 30 primary and three metastatic brain tumors, 11 infectious/inflammatory lesions, three vascular, one degenerative disease, and one developmental malformation. Upon univariate analysis of 21 MR signs, there were seven that had a significant association with neoplasia: single lesion (P = 0.004), shape (P = 0.015), mass effect (P = 0.002), dural contact (P = 0.04), dural tail (P = 0.005), lesions affecting adjacent bone (P = 0.008), and contrast enhancement (P = 0.025). Increasing age was also found to be associated with neoplasia (P = 0.0001). MR signs of non-neoplastic brain diseases in dogs and cats were more variable than those of brain neoplasia. 相似文献
106.
Christopher J Bonar Albert H Lewandowski Baha Arafah Charles C Capen 《Journal of zoo and wildlife medicine》2005,36(4):719-723
A 43 yr-old female African elephant (Loxodonta africana) collapsed acutely and died. Necropsy revealed an enlarged right adrenal medulla. Histologic appearance was typical of pheochromocytoma. Special stains and electron microscopy demonstrated chromaffin granules, suggesting that the tumor was derived from catecholamine secreting cells of the adrenal medulla, and may have been functionally secretory. Serum levels of both norepinephrine and epinephrine were elevated at time of death, supporting the functional nature of the tumor. Histologic findings of arteriolar sclerosis and smooth muscle hyperplasia suggested that the animal may have suffered from chronic systemic hypertension. Pheochromocytoma should be considered as a differential diagnosis in cases of suspected hypertension and acute death in elephants. 相似文献
107.
Christopher S Hanley Heather A Simmons Roberta S Wallace Victoria L Clyde 《Journal of zoo and wildlife medicine》2005,36(3):515-519
A 10.5-yr-old male spotted hyena (Crocuta crocuta) developed acute, severe erythematous and ulcerative dermatitis of the hindquarters, feet, face, and ears 19 days after receiving a recombinant canary pox vectored canine distemper vaccine. Biopsies of the lesions supported a diagnosis of erythema multiforme (EM), which is an immune-mediated disorder that can occur days to months after exposure to antigenic stimuli. During the lengthy recovery, esophageal regurgitation and ulceration developed either as complications of the disease or secondary to therapy. The esophageal disease was managed with metoclopramide, sulcrafate, omeprazole, and frequent feedings. The distemper vaccine is postulated to have been the inciting cause of EM in this animal. 相似文献
108.
Luis R Padilla Christopher J Dutton Joan Bauman Mary Duncan 《Journal of zoo and wildlife medicine》2005,36(3):498-503
A 2-yr-old Arabian oryx (Oryx leucoryx) was presented for evaluation of abnormal genitalia and infantile behavior. The oryx had a penis and a scrotum, but testes were not palpable within the scrotum or inguinal canal. The total serum testosterone for the individual was lower than in age-matched males of the same species. Surgical exploration showed markedly hypoplastic intra-abdominal gonads, which demonstrated both testicular and uterine tissue on histologic examination. After karyotype analysis, the individual was classified as an XY male pseudohermaphrodite. This condition resembles two human intersex syndromes: embryonic testicular regression syndrome and partial gonadal dysgenesis syndrome, which occur in familial lines. 相似文献
109.
Petr Masner Christopher C. Steel Rolf Furter Hans Peter Isenring Gottfried Oesterhelt Hugo Ziegler Peter Zobrist 《Pest management science》1992,35(4):339-347
The activity of five experimental fungicides combining structural elements responsible for sterol C-14 demethylase inhibition and sterol nuclear double-bond transformations has been investigated by examining sterol accumulation in Ustilago maydis (DC.) Corda, inhibition of sterol-biosynthesis enzymes in Saccharomyces cerevisiae Meyer using a cell-free system and protective activity in cereals against Erysiphe graminis DC. and Puccinia coronata Corda. Combining the fenpropidin/fenpropimorph basic structure with a pyridine moiety offered no advantage in fungicidal activity. However, the combination of the pyrifenox structure with a morpholine moiety yielded a compound which was a good inhibitor of C-14 demethylase and Δ8 → Δ7 isomerase in vitro and gave good cereal protection. 相似文献
110.
Suzanne J. Clark Nicola P. Coward Glenn W. Dawson Ian F. Henderson Andrew P. Martin 《Pest management science》1995,44(4):381-388
Two related iron chelates, one toxic to slugs by ingestion, the other not, were introduced into the foregut of D. reticulatum. The subsequent movement and redistribution of the metal within the slug tissues was studied by labelling the chelates with the radioactive isotope 55Fe. In slugs which survived treatment approximately half of the 55Fe was voided in faeces. The iron retained became unevenly distributed, the highest concentration occurring in the digestive gland, irrespective of the chelate used. At high doses, slugs treated with tris(1-oxo-1,2-diazabutan-2-oxido)Fe(III) were fatally poisoned while those treated with the homologue, tris(1-oxo-1,2-diazaoctan-2-oxido)Fe(III) were not. Slugs killed by the toxic chelate consistently contained proportionally less iron in the digestive gland and proportionally more in the body wall and reproductive system. Dosing slugs already killed by carbon dioxide asphyxiation gave a similar pattern, suggesting that the greater mobility of the iron from the toxic chelate was not a function of the slugs' metabolism. 相似文献