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201.
Effects of spray-dried animal plasma (SDAP) on intake and apparent digestibility of major dietary components were determined using 22 adult Beagles. Trials 1 and 2 used six and eight dogs, respectively, in a switchback design using 10-d periods. Trial 3 used eight dogs in a replicated 4 x 4 Latin square design with 15-d periods. The final 5 d of each period were used for measurement of intake and fecal collections. In Trial 1, dry extruded dog food kibbles were coated with 5% tallow, 2% commercial flavor, and 0 or 2% SDAP (as-fed basis). In Trial 2, commercially available dry dog food, previously coated with fat and flavor were coated with 0 or 2% SDAP. In Trial 3, SDAP (0, 1, 2, or 3%) was blended with other ingredients and extruded (as-fed basis). Kibbles were subsequently coated with 5% poultry fat and 1% commercial flavor. Intake, fecal consistency, and apparent digestibility of nutrients were determined. Addition of SDAP did not markedly affect chemical composition of diets and did not affect intake. Digestibility of DM was improved (P < 0.04) an average of 3.2% when 2% SDAP was included in the diet for all trials. Organic matter digestibility was improved (P < 0.01) in Trials 2 and 3 by an average of 2.9%. Also, digestibility of crude fiber (Trials 1 and 2) or total dietary fiber (Trial 3) was increased with addition of SDAP to the diet (P < 0.01). Fecal DM excretion was decreased by an average of 15% across all trials with the addition of SDAP. Spray-dried animal plasma was an acceptable ingredient in dry dog food preparations, resulting in improved digestion and decreased fecal output. Changes in digestion that occurred with addition of SDAP suggested alteration in digestive capacity in dogs. 相似文献
202.
Campbell JM Russell LE Crenshaw JD Behnke KC Clark PM 《Journal of animal science》2006,84(9):2501-2508
A series of 4 experiments evaluated effects of mash conditioning temperature from a pellet mill or expander on performance of broilers fed pelleted diets containing spray-dried plasma (SDP). All experiments utilized Ross x Ross 308 male broilers randomly assigned to their respective treatments (6 or 10 broilers/pen and 8 or 10 pens/treatment). Treatments in Exp. 1 consisted of a control (0% SDP), SDP coated postpelleting, or SDP blended into the meal prepelleting. Experiment 2 and 3 included the same 3 treatments as in Exp. 1 but with additional treatments of SDP blended into the meal and conditioned at 90 or 95 degrees C before pelleting. In Exp. 4, treatments consisted of a control (0% SDP) or SDP blended into the meal and pelleted (85 degrees C conditioning temperature) or expanded (149 degrees C final effective temperature) and then pelleted. Corn-soybean meal-based diets were formulated to be equal in lysine and ME in all experiments. Pelleted diets were conditioned for 15 s at 85 degrees C, and expanded diets were conditioned at 95 degrees C, 29.7 MJ/t, 13.95 kg/cm2 cone pressure, exit temperature of 149 degrees C, and then pelleted through a 4 x 32-mm die. In Exp. 1, ADG and feed intake were improved (P < 0.05) for broilers fed SDP from d 1 to 28 of age, with greater BW at d 42. In Exp. 2, both in early (d 1 to 28 of age) phases, and overall (d 1 to 42 of age), broilers fed SDP had improved (P < 0.05) gain and efficiency. In Exp. 3, ADG, feed intake, efficiency of gain, and BW were improved (P < 0.01) for broilers fed SDP from d 1 to 21 of age, regardless of conditioning temperature. In Exp. 4, broilers fed SDP had improved (P < 0.05) gain, BW, and feed intake regardless of processing method. Overall, the results of all of the experiments demonstrated that pellet conditioning temperature from 85 to 95 degrees C and expander temperatures to 149 degrees C did not impair the positive growth effects of SDP in pelleted or expanded broiler feed. 相似文献
203.
204.
Campbell SJ Marks SL Yoshimoto SK Riel DL Fascetti AJ 《Journal of the American Animal Hospital Association》2006,42(3):197-206
Sixteen dogs and cats with a variety of primary diseases were retrospectively evaluated following endoscopic placement of a one-step low-profile gastrostomy device. Overall, the devices were well tolerated, with most complications being minor in nature. Complications included bloody or purulent peristomal discharge, peristomal swelling, peristomal inflammation, discomfort associated with the device, leaking through the device, chewing at the device, premature removal of the device, peritonitis, and aspiration pneumonia. Dogs survived for up to 2241 days, and cats survived for up to 593 days after initial device placement. The median survival time after device insertion for dogs was 89 days, and for cats it was 87 days. 相似文献
205.
S Naik N Bouladoux C Wilhelm MJ Molloy R Salcedo W Kastenmuller C Deming M Quinones L Koo S Conlan S Spencer JA Hall A Dzutsev H Kong DJ Campbell G Trinchieri JA Segre Y Belkaid 《Science (New York, N.Y.)》2012,337(6098):1115-1119
Intestinal commensal bacteria induce protective and regulatory responses that maintain host-microbial mutualism. However, the contribution of tissue-resident commensals to immunity and inflammation at other barrier sites has not been addressed. We found that in mice, the skin microbiota have an autonomous role in controlling the local inflammatory milieu and tuning resident T lymphocyte function. Protective immunity to a cutaneous pathogen was found to be critically dependent on the skin microbiota but not the gut microbiota. Furthermore, skin commensals tuned the function of local T cells in a manner dependent on signaling downstream of the interleukin-1 receptor. These findings underscore the importance of the microbiota as a distinctive feature of tissue compartmentalization, and provide insight into mechanisms of immune system regulation by resident commensal niches in health and disease. 相似文献
206.
Inamori K Yoshida-Moriguchi T Hara Y Anderson ME Yu L Campbell KP 《Science (New York, N.Y.)》2012,335(6064):93-96
Posttranslational modification of alpha-dystroglycan (α-DG) by the like-acetylglucosaminyltransferase (LARGE) is required for it to function as an extracellular matrix (ECM) receptor. Mutations in the LARGE gene have been identified in congenital muscular dystrophy patients with brain abnormalities. However, the precise function of LARGE remains unclear. Here we found that LARGE could act as a bifunctional glycosyltransferase, with both xylosyltransferase and glucuronyltransferase activities, which produced repeating units of [-3-xylose-α1,3-glucuronic acid-β1-]. This modification allowed α-DG to bind laminin-G domain-containing ECM ligands. 相似文献
207.
Murray D. Jelinski John R. Campbell Leigh B. Rosengren 《The Canadian veterinary journal. La revue veterinaire canadienne》2012,53(6):673-675
A manpower survey of veterinary practices in western Canada found that there were potentially 314 full-time equivalent veterinary vacancies. However, only 8% of the respondents were in urgent need of another veterinarian. The results underscore that hiring intentions are best viewed as a continuum and not as a simple dichotomous variable: “Looking to hire? (Yes/No)”. 相似文献
208.
Koya V Campbell AM McLaughlin PJ Tewari D Wilson RP Cooper TK 《Veterinary pathology》2012,49(3):528-531
Seventy-four 9-week old female C57BL/6J mice housed in a conventional facility were manipulated to induce experimental autoimmune encephalomyelitis, among which 26 developed clinical signs including lethargy, absence of defecation, and abdominal distension. By gross necropsy examination, there was distension of the cecum and colon with fecal impaction. By histologic examination, there was severe ulcerative and proliferative typhlocolitis. Fecal ELISA confirmed the presence of toxins A and B of Clostridium difficile. Alteration in immune status of the immunocompetent mice, due to stress caused by experimental manipulation or autoimmune disease, may have led to intestinal dysbiosis, followed by opportunistic infections resulting in C. difficile-associated disease. This report brings to light the occurrence of the disease in immunocompetent laboratory mice during experimental manipulations associated with alteration in immune status, and it discusses potential hazards associated with conventional housing within a hospital-associated research institute. 相似文献
209.
Background
Intake of colostrum after birth is essential to stimulate intestinal growth and function, and to provide systemic immunological protection via absorption of Immunoglobulin G (IgG). The birth order and weight of 745 piglets (from 75 litters) were recorded during a one-week period of farrowing. Only pigs weighing greater than 0.68 kg birth weight were chosen for the trial. Sow colostrum was collected during parturition, and piglets were bled between 48 and 72 hours post-birth. Piglet serum IgG and colostral IgG concentrations were determined by radial immunodiffusion.Results
Sow parity had a significant (P < 0.001) effect on sow colostral IgG concentration, being 5% higher in multiparous females. Sow colostral IgG concentration explained 6% and piglet birth order accounted for another 4% of the variation observed in piglet serum IgG concentration (P < 0.05); however, birth weight had no detectable effect. Piglet serum IgG concentration had both a linear (P < 0.05) and quadratic effect (P < 0.05) on % survival. Piglets with 1,000 mg/dl serum IgG or less (n=24) had a 67% survival; whereas, piglets with IgG concentrations between 2250 to 2500 mg/dl (n=247) had a 91% survival. Birth order had no detectable effect on survival, but birth weight had a positive linear effect (P < 0.05). Piglets weighing 0.9 kg (n = 107) at birth had a 68% survival rate, and those weighing 1.6 kg (n = 158) had an 89% survival.Conclusion
We found that the combination of sow colostrum IgG concentration and birth order can account for 10% of the variation of piglet serum IgG concentration and that piglets with less than 1,000 mg/dl IgG serum concentration and weight of 0.9 kg at birth had low survival rate when compared to their larger siblings. The effective management of colostrum uptake in neonatal piglets in the first 24 hrs post-birth may potentially improve survival from birth to weaning. 相似文献210.
Eloisa Ortega-Vargas Silvia López-Ortiz Juan Andrés Burgueño-Ferreira W. Bruce Campbell Jesús Jarillo-Rodríguez 《Agroforestry Systems》2013,87(4):917-927
Guazuma ulmifolia was experimentally pruned to determine when pruning should begin during the rainy season in order to extend the production of green tree-forage during the dry season. Three prunings (P-1, P-2, and P-3) were performed (5 weeks apart) during the rainy season (August, September, and October) and four forage harvests (C-a, C-b, C-c, and C-d) (3 weeks apart) took place during the dry season (February, March, and April). Over 2 years, forage biomass production was evaluated as total biomass (g dry matter tree?1), biomass of the morphological components (leaves, stems, and dead matter), and nutritional quality (crude protein, fiber, lignin, and digestibility). Date of pruning affected the production of total biomass (P = 0.001) with the earliest pruning (P-1) yielding the greatest forage quantity, while stems (P = 0.022) and dead matter (P = 0.032) varied due to a year by pruning interaction. Total biomass, leaves, stems, and dead matter varied by the interaction between forage harvest and year for all four variables (P < 0.037). In both years, the largest forage harvest occurred in C-b (P < 0.05), leaf production was highest in C-a and C-b (P < 0.001), stem production was greatest in C-b (P = 0.013) and dead matter was highest in C-b and C-d (P = 0.002). Leaf crude protein ranged between 10 and 19 %, and the interaction of pruning by forage harvest by year was significant (P = 0.035). Digestibility, neutral and acid detergent fiber and lignin differed significantly because of the interaction between forage harvest and year (P < 0.005), with February showing the lowest values for fiber and the highest digestibility. The best time to prune G. ulmifolia is in August so that the young trees will produce more total biomass with a higher crude protein content. The most suitable moment for forage harvest is in February when the trees have more leaves with greater digestibility and less fiber. 相似文献