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201.
In conscious pigs the influence of intravenous infusion of live E. coli (7×108/kg), of the equivalent amount of endotoxin (20 g/kg) or of a high dose of endotoxin (2.5 mg/kg) on the hemodynamic, clinical and pathological parameters and on survival rate was studied. E. coli and endotoxin infusion resulted in pulmonary hypertension, systemic arterial hypotension, a decrease in cardiac output and an increase in heart rate. Clinical signs were characterized by respiratory and nervous disturbances, whereas necropsy revealed hemorrhages and edema in several organs. Although these findings were similar in the three groups, a marked difference in lethality was observed. Infusion of E. coli or of the high dose of endotoxin resulted in a significant mortality, whereas all pigs survived the infusion of the low dose of endotoxin. This suggests that the lethal pathophysiological mechanisms may only become activated when a sufficient amount of endotoxin is released into the circulation. 相似文献
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Norman C 《Science (New York, N.Y.)》1988,242(4884):1372-1374
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The objective of this study was to investigate the development of maternal-filial social attachments between ewes and alien lambs using the technique of "restraint fostering." Forty-eight to 72 h after parturition, 22 Targhee -type ewes were separated from their natural lambs, placed in restraining devices ( stanchions ) and each exposed to a single alien lamb. After a period of 1 or 4 d of restraint, the ewes were subjected to five 10-min lamb acceptance tests over a 48-h period. The observer recorded butts and butt attempts by the ewe and successful and unsuccessful suckle attempts by the lamb. The ewe-lamb pairs were then housed in pens with other groups of ewes and lambs and observed intermittently for acceptance behaviors. Six of the 14 ewes restrained for 4 d and none of the eight ewes restrained for 24 h met the criterion for successful adoption within 48 h. After being housed in group pens, adoptions were achieved by three ewes in the 1-d group and an additional four ewes in the group restrained for 4 d. Ewes restrained for 24 h were significantly more aggressive toward fostered young than ewes restrained for 4 d. In addition, the proportion of successful suckling attempts was significantly lower for lambs fostered on ewes in the 1-d group. Both groups showed a decline in butts and butt attempts over successive acceptance tests, but while the proportion of successful suckling attempts declined for lambs housed with 1-d ewes, they increased over time for lambs fostered on ewes restrained for 4 d.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
209.
Thurley DC 《New Zealand veterinary journal》1984,32(3):25-29
The teeth and various supporting and ancillary tissues were examined post mortem from two flocks of sheep, one of which had previously shown high deciduous incisor wear. Sheep were killed in groups selected on clinical signs at equivalent ages from birth to 116 weeks of age. At the end of this time the lengths of clinical crowns of the remaining deciduous incisor teeth in the high wear flock were not measurable, whereas the other flock had up to 5.5 mm in visible crown. Using the cingulum as a marker, measurements were made from extracted teeth of the attrition of the crown and size of the root. The tooth root did not grow substantially longer after the 13th week of the sheep;s life. Wear facets were just visible in some sheep at six weeks. More rapid wear occurred three times in the high wear flock. The first of these was relatively small and occurred between the 13th and 27th week of age in I1 and I2. The second was larger and occurred between the 38th and 57th week of age in the winter/spring period. A third period of wear, which was not measured from the cingulum, because this structure had by then been worn away, was seen in the remaining deciduous teeth between the ages of 91 and 110 weeks of age, i.e., during the second winter and spring. In the low wear flock the first of these periods of wear did not occur, the second was of shorter duration and smaller size, and the third equivocal. Eruption of the teeth after the 6th week was principally passive. There was no difference in the degree of wear of the molar teeth from the two flocks. Histological examination showed that the wear was compensated for by the deposition of reparative dentine in the pulp cavity. This usually gave the appearance of an ordered process. However, when wear was excessively rapid, a different, less orderly form of reparative dentine was laid down. In a few cases the reparative process was not fast enough, and a connection developed between the mouth and the pulp causing pulpitis. There was no histological evidence that the supportive tissues of the teeth, or the upper dental pad, contributed to the excessive wear. 相似文献
210.
A method for the control of ovine footrot is described which utilises the most appropriate measures to suit the circumstances for individual properties. This approach was used to eradicate the disease from three Central Otago fine-wool properties wintering in excess of 35,000 sheep on widely differing classes of land. This programme incorporates the use of proven.techniques and suitable planning together with input from the rural veterinarian, who plays an important role in demonstration and advising on control measures. 相似文献