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161.
In an effort to identify improved methods for diagnosis of infection in the neonatal foal, clinical records from 38 septicaemic foals of less than one week of age were examined for trends in history, physical examination and clinicopathological findings. The survival rate of septicaemic foals, 26 per cent, was markedly less than the rate for all other foal admissions. Blood cultures were valuable in diagnosis and treatment of septicaemia and identified a preponderance of Gram-negative infection. Zinc sulphate turbidity test results were abnormally low in all septicaemic foals tested. The clinical course was often distinguished by severe complications and multiple organ dysfunction, leading to death. Conditions present in the mare pre-partum resulted in weak or diseased foals; bacterial placentitis, vaginal discharge and premature lactation were most common. There was no single diagnostic criterion of the septicaemic foal. Fever was not a consistent finding. The most useful white blood cell parameters were neutropenia, the presence of band neutrophils (greater than 0.2 X 10(9)/litre) and toxic changes in the neutrophil population. Hypoglycaemia, metabolic acidosis and hypoxaemia were also common findings. 相似文献
162.
The anthelmintic potential of epsiprantel, 2-(cyclohexylcarbonyl)-4-oxo-1,2,3,4,6,7,8,12b-octahydropyrazin [2,1-a] [2]benzapine, was revealed using the tapeworms Dipylidium caninum and Taenia taeniaeformis in the cat, and Taenia pisiformis and T. hydatigena in the dog. Subsequent controlled tests in cats demonstrated oral efficacy of 100% against D. caninum with a single dose of 2.5 mg/kg. Although consistently 100% effective against T. taeniaeformis at 5 mg/kg, a single worm was found in one cat treated at 7.5 mg/kg. In experimental infections of Taenia pisiformis in dogs, 100% activity was achieved from a single oral dose of 1 mg/kg. No adverse reaction or drug-associated toxicity were observed at dose levels used. 相似文献
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Brewer GJ 《Science (New York, N.Y.)》1985,228(4705):1305-1306
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Xu Genyan Zhang Sha Song Jing Brewer Roger Gao Hui 《Journal of Soils and Sediments》2019,19(10):3585-3596
Journal of Soils and Sediments - Soil management strategies for agricultural lands contaminated with potentially toxic trace elements, especially cadmium (Cd), are still inadequate and require a... 相似文献
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Spanu PD Abbott JC Amselem J Burgis TA Soanes DM Stüber K Ver Loren van Themaat E Brown JK Butcher SA Gurr SJ Lebrun MH Ridout CJ Schulze-Lefert P Talbot NJ Ahmadinejad N Ametz C Barton GR Benjdia M Bidzinski P Bindschedler LV Both M Brewer MT Cadle-Davidson L Cadle-Davidson MM Collemare J Cramer R Frenkel O Godfrey D Harriman J Hoede C King BC Klages S Kleemann J Knoll D Koti PS Kreplak J López-Ruiz FJ Lu X Maekawa T Mahanil S Micali C Milgroom MG Montana G Noir S O'Connell RJ Oberhaensli S 《Science (New York, N.Y.)》2010,330(6010):1543-1546
Powdery mildews are phytopathogens whose growth and reproduction are entirely dependent on living plant cells. The molecular basis of this life-style, obligate biotrophy, remains unknown. We present the genome analysis of barley powdery mildew, Blumeria graminis f.sp. hordei (Blumeria), as well as a comparison with the analysis of two powdery mildews pathogenic on dicotyledonous plants. These genomes display massive retrotransposon proliferation, genome-size expansion, and gene losses. The missing genes encode enzymes of primary and secondary metabolism, carbohydrate-active enzymes, and transporters, probably reflecting their redundancy in an exclusively biotrophic life-style. Among the 248 candidate effectors of pathogenesis identified in the Blumeria genome, very few (less than 10) define a core set conserved in all three mildews, suggesting that most effectors represent species-specific adaptations. 相似文献