Future Veterinary Diagnostics

The development of rapid, accurate, and sensitive diagnostic methods for detecting pathogens is the basis for treating, controlling, and eradicating infectious diseases of veterinary importance. Scientific and technological advancements have revolutionized the field of veterinary diagnostics. Genome sequencing has allowed efficient, sensitive, and specific diagnostic assays to be developed based on the detection of nucleic acids. The integration of advances in biochemistry, proteomics, engineering, and medicine offers enormous potential for the rapid and accurate diagnosis of viral, microbial, genetic, and metabolic disease. In the future, polymerase chain reaction assays, microarray testing, genomic analysis, and metabolic profiling will be accomplished in a rapid, portable, sensitive, and cost-efficient manner.     

中文版阔叶材胶合板标准面市

2004年10月25日,美国弗吉尼亚州亚历山大(ALEXANDRIA,Va)消息。国际木制品协会(International Wood Products Association,IWPA)发布公告,其制订的通用工业标准,《IHPA Grade等级进口阔叶材胶合板采购标准》最近翻译出版了中文版(繁体)。     

Triggering a cell shape change by exploiting preexisting actomyosin contractions

Apical constriction changes cell shapes, driving critical morphogenetic events, including gastrulation in diverse organisms and neural tube closure in vertebrates. Apical constriction is thought to be triggered by contraction of apical actomyosin networks. We found that apical actomyosin contractions began before cell shape changes in both Caenorhabitis elegans and Drosophila. In C. elegans, actomyosin networks were initially dynamic, contracting and generating cortical tension without substantial shrinking of apical surfaces. Apical cell-cell contact zones and actomyosin only later moved increasingly in concert, with no detectable change in actomyosin dynamics or cortical tension. Thus, apical constriction appears to be triggered not by a change in cortical tension, but by dynamic linking of apical cell-cell contact zones to an already contractile apical cortex.     

Comparative Histomorphological Review of Rat and Human Hepatocellular Proliferative Lesions

In this comparative review, histomorphological features of common nonneoplastic and neoplastic hepatocyte lesions of rats and humans are examined using H&E-stained slides. The morphological similarities and differences of both neoplastic (hepatocellular carcinoma and hepatocellular adenoma) and presumptive preneoplastic lesions (large and small cell change in humans and foci of cellular alteration in rats) are presented and discussed. There are major similarities in the diagnostic features, growth patterns and behavior of both rat and human hepatocellular proliferative lesions and in the process of hepatocarcinogenesis. Further study of presumptive preneoplastic lesions in humans and rats should help to further define their role in progression to hepatocellular neoplasia in both species.     

Induction of hepatic microsomal enzymes in chickens effected by various persistent foreign materials]

Changes in the levels of microsomal proteins, in the activity of microsomal aniline hydroxylase, and in the effectivity of Thiopental were studied in chickens given the Czechoslovak-produced type of polychlorinated biphenyls - Delor 103. The increased activity of aniline hydroxylase and the decrease of Thiopental sleeping time in chickens exposed to the action of Delor 103 indicate that this preparation is able to induce liver microsomal enzymes in doses as low as 5 mg per kg of feed. The induction of liver microsomal enzymes appears to be an important factor, able to exercise a direct influence on the biotransformation of various biologically important substances in the organism of chickens.