Resistance to prophylactic treatment with macrocyclic lactone anthelmintics in Teladorsagia circumcincta

Sixty-four Romney ewe lambs were allocated to 12 groups on the basis of liveweight. Four groups (n=5) were administered oral ivermectin (IVM), 4 (n=6) oral moxidectin (MOX) and the remaining 4 (n=5) controlled-release capsules containing IVM (IVM-CRCs). Nine and 10 days later, the groups within each treatment type were challenged with infective-stage larvae (L3) of 1 of 4 different isolates of Teladorsagia circumcincta (two doses each of 5000 L3). The first of these (S) was known to be anthelmintic-susceptible; the second (OR) was a multiple anthelmintic-resistant strain recovered from the field following therapeutic failure of both ivermectin and moxidectin and subsequently maintained in the laboratory without further anthelmintic selection; the third (R) was derived from OR but had been passaged for five generations indoors with each generation being screened with all three broad-spectrum anthelmintic classes; and the fourth (RxS) was an F1 cross between the R and S isolates. As anticipated, because of its limited residual activity, IVM had no significant effect on the establishment, 9 and 10 days post-treatment, of any of the parasite isolates. In contrast MOX, which has greater residual activity, was highly effective at preventing the establishment of the S isolate but showed no significant effect against the OR, R or RxS isolates. The IVM-CRC was also highly effective at preventing the establishment of the S isolate and furthermore it significantly reduced establishment of both the OR and RxS isolates, although it had no significant effect against the R isolate. The results suggest that with respect to the establishment of T. circumcincta L3s following anthelmintic treatment, macrocyclic lactone (ML) resistance is effectively a dominant trait in the presence of MOX, while it behaves as a partially dominant/recessive trait under treatment with IVM-CRCs. The potential implications of this finding in relation to selection for ML resistance in T. circumcincta are discussed.     

额济纳胡杨林土壤含水量时空变化的研究

使用管状土壤水分仪,对额济纳胡杨林、沙枣林、柽柳林以及其它不同样地的土壤含水量时空变化进行了调查研究。结果表明,大部分样地有大约20CM的干沙层,使表层土壤含水量最低;土壤剖面的30~150CM土层内,随土壤深度的增加,土壤含水量逐渐增大;沙枣林和柽柳林的土壤含水量明显高于胡杨林土壤含水量;土壤质地的变化和三种林型耗水量的差异是土壤含水量高低变化的原因;2004年5月份的土壤含水量明显高于2003年7月份的土壤含水量。     

陕北毛乌素沙地仁用杏丰产栽培技术体系

针对陕北毛乌素沙地地势较为平埋，光热资源丰富，水资源相对充足，但干旱少雨，降水集中，蒸发量大，风沙危害频繁，土质疏松、漏肥、漏水现象严重等特殊的自然条件，提出了适宜该地区采用的仁用杏丰产栽培技术体系。     

基于风云3B微波亮温数据的内蒙古草原牧区雪深反演研究

基于内蒙古草原牧区2011~2013年两个积雪季的国产卫星FY-3B双极化亮温数据,通过使用2012年MODIS的MCD12Q1土地覆盖类型产品数据提取内蒙古牧区草地植被类型,同时使用与FY-3B数据同期的MOD10A1日积雪覆盖产品剔除研究区内无积雪覆盖的像元,进而得到内蒙古草原牧区有积雪覆盖区域的FY-3B影像各像元的亮温数据。将亮温数据与研究区内相应的野外固定实验站观测数据及呼伦贝尔市的7个气象站点雪深观测数据建立回归拟合关系,初步建立了基于FY-3B亮温数据的适合于内蒙古草原牧区的雪深反演模型,模型参数拟合决定系数R2为0.59。使用2012年研究区雪深观测值检验模型,均方根误差为3.12cm,平均相对误差为18%,表明所建立的雪深反演模型能够较好地估算和识别内蒙古草原牧区雪深的空间分布特征。     

Cefquinome Concentrations in Endometrium after Intrauterine Treatment of Cobactan 4.5%® in Mares and Inflammatory Response of the Endometrium to this Treatment

This study was conducted to measure the concentration of cefquinome in the endometrium of mares after intrauterine treatment and to evaluate associated inflammation. Mares (n = 14) were randomly assigned to one of the following groups: (i) control (n = 4) were either not treated (n = 2) or received (n = 2) lactated Ringer's intrauterine for 1 or 3 days; (ii) treated mares (n = 10) received intrauterine cefquinome for 1 or 3 days. After at least 10 days had passed following the last treatment and ovulation, mares were given Prostaglandin F2α (PGF2α) and were randomly assigned to an alternate treatment. Endometrial biopsy samples were taken at 2, 8, 24 and 48 h, or at 4, 12 and 36 h, after the last treatment. Biopsy samples were taken at the same time points from control mares (n = 2) and lactated Ringer-treated mares (n = 2). Cefquinome concentrations were quantified using a high-performance liquid chromatography (HPLC) assay and inflammation was assessed using haematoxylin and eosin (H&E)-stained sections. Concentrations of cefquinome [559 (1 day) and 595 μg/g (3 days) at 2 h, and 403 (1 day) and 370 μg/g (3 days) at 4 h] were similar between treatment groups at 2 and 4 h after treatment (p > 0.05). At 8 h, as well as at 24 and 48 h, concentrations were greater in the 3-day group (17 vs 301 μg/g, 3 vs 80 μg/g and 0.1 vs 0.2 μg/g, respectively) (p < 0.05). No significant differences (p > 0.05) in the inflammatory response at 2–48 h after treatment were found between groups.     

氨气对肉鸡健康的影响及应对措施

氨气是鸡舍内危害最大的气体,长期氨气应激不利于肉鸡的健康生长。加强对肉鸡舍氨气浓度的监测,研究氨气对肉鸡健康的影响以及减排措施对指导鸡舍氨气浓度的合理调控和健康养殖的发展具有重要意义。本文主要通过综述舍内氨气的来源,氨气对肉鸡生长性能、屠宰性能和肉品质、免疫功能、呼吸道、繁殖性能、福利等方面的影响以及舍内氨气的监测和减排措施,为深入研究氨气对肉鸡健康影响的作用机制以及合理调控肉鸡舍内氨气浓度提供参考。