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11.
P R Fox T A Sos B R Bond 《Journal of the American Veterinary Medical Association》1985,187(3):275-276
A fragment of an 18-gauge catheter was inadvertently severed during catheterization of the cephalic vein in a 7-year-old Golden Retriever. Under fluoroscopic guidance, the fragment was retrieved successfully from the right ventricle, using a self-constructed, loop-snare catheter. 相似文献
12.
Georg Lehner Monika Linek Ross Bond David H. Lloyd Ellen Prenger-Berninghoff Nina Thom Iris Straube Kristien Verheyen Anette Loeffler 《Veterinary microbiology》2014
Methicillin-resistant Staphylococcus pseudintermedius (MRSP) has emerged as a highly drug-resistant small animal veterinary pathogen. Although often isolated from outpatients in veterinary clinics, there is concern that MRSP follows a veterinary-hospital-associated epidemiology. This study's objective was to identify risk factors for MRSP infections in dogs and cats in Germany. Clinical isolates of MRSP cases (n = 150) and methicillin-susceptible S. pseudintermedius (MSSP) controls (n = 133) and their corresponding host signalment and medical data covering the six months prior to staphylococcal isolation were analysed by multivariable logistic regression. The identity of all MRSP isolates was confirmed through demonstration of S. intermedius-group specific nuc and mecA. In the final model, cats (compared to dogs, OR 18.5, 95% CI 1.8–188.0, P = 0.01), animals that had been hospitalised (OR 104.4, 95% CI 21.3–511.6, P < 0.001), or visited veterinary clinics more frequently (>10 visits OR 7.3, 95% CI 1.0–52.6, P = 0.049) and those that had received topical ear medication (OR 5.1, 95% CI 1.8–14.9, P = 0.003) or glucocorticoids (OR 22.5, 95% CI 7.0–72.6, P < 0.001) were at higher risk of MRSP infection, whereas S. pseudintermedius isolates from ears were more likely to belong to the MSSP-group (OR 0.09, 95% CI 0.03–0.34, P < 0.001). These results indicate an association of MRSP infection with veterinary clinic/hospital settings and possibly with chronic skin disease. There was an unexpected lack of association between MRSP and antimicrobial therapy; this requires further investigation but may indicate that MRSP is well adapted to canine skin with little need for selective pressure. 相似文献
13.
D. A. Bond G. J. Jellis G. G. Rowland J. Le Guen L. D. Robertson S. A. Khalil L. Li-Juan 《Euphytica》1993,73(1-2):151-166
Progress is being made, mainly by ICARDA but also elsewhere, in breeding for resistance to Botrytis, AScochyta, Uromyces, and Orobanche; and some lines have resistance to more than one pathogen. The strategy is to extend multiple resistance but also to seek new and durable forms of resistance. Internationally coordinated programs are needed to maintain the momentum of this work.Tolerance of abiotic stresses leads to types suited to dry or cold environments rather than broad adaptability, but in this cross-pollinated species, the more hybrid vigor expressed by a cultivar, the more it is likely to tolerate various stresses. 相似文献
14.
Bond CT Sprengel R Bissonnette JM Kaufmann WA Pribnow D Neelands T Storck T Baetscher M Jerecic J Maylie J Knaus HG Seeburg PH Adelman JP 《Science (New York, N.Y.)》2000,289(5486):1942-1946
In excitable cells, small-conductance Ca2+-activated potassium channels (SK channels) are responsible for the slow after-hyperpolarization that often follows an action potential. Three SK channel subunits have been molecularly characterized. The SK3 gene was targeted by homologous recombination for the insertion of a gene switch that permitted experimental regulation of SK3 expression while retaining normal SK3 promoter function. An absence of SK3 did not present overt phenotypic consequences. However, SK3 overexpression induced abnormal respiratory responses to hypoxia and compromised parturition. Both conditions were corrected by silencing the gene. The results implicate SK3 channels as potential therapeutic targets for disorders such as sleep apnea or sudden infant death syndrome and for regulating uterine contractions during labor. 相似文献
15.
Gaudi BS Bennett DP Udalski A Gould A Christie GW Maoz D Dong S McCormick J Szymanski MK Tristram PJ Nikolaev S Paczynski B Kubiak M Pietrzynski G Soszynski I Szewczyk O Ulaczyk K Wyrzykowski L;OGLE Collaboration Depoy DL Han C Kaspi S Lee CU Mallia F Natusch T Pogge RW Park BG;MuFUN Collaboration Abe F Bond IA Botzler CS Fukui A Hearnshaw JB Itow Y Kamiya K Korpela AV Kilmartin PM Lin W Masuda K Matsubara Y Motomura M Muraki Y Nakamura S Okumura T Ohnishi K Rattenbury NJ Sako T Saito T Sato S 《Science (New York, N.Y.)》2008,319(5865):927-930
Searches for extrasolar planets have uncovered an astonishing diversity of planetary systems, yet the frequency of solar system analogs remains unknown. The gravitational microlensing planet search method is potentially sensitive to multiple-planet systems containing analogs of all the solar system planets except Mercury. We report the detection of a multiple-planet system with microlensing. We identify two planets with masses of approximately 0.71 and approximately 0.27 times the mass of Jupiter and orbital separations of approximately 2.3 and approximately 4.6 astronomical units orbiting a primary star of mass approximately 0.50 solar mass at a distance of approximately 1.5 kiloparsecs. This system resembles a scaled version of our solar system in that the mass ratio, separation ratio, and equilibrium temperatures of the planets are similar to those of Jupiter and Saturn. These planets could not have been detected with other techniques; their discovery from only six confirmed microlensing planet detections suggests that solar system analogs may be common. 相似文献
16.
Pseudomonas aeruginosa: growth in distilled water from hospitals 总被引:37,自引:0,他引:37
Pseudomonas aeruginosa can grow relatively fast in distilled water obtained in hospitals and achieve high cell contaminations which remain stable for long periods of time. Cells grown in distilled water react quite differently to chemical and physical stresses than cells grown in standard laboratory culture media. 相似文献
17.
18.
Iceberg discharges into the north atlantic on millennial time scales during the last glaciation 总被引:2,自引:0,他引:2
High-resolution studies of North Atlantic deep sea cores demonstrate that prominent increases in iceberg calving recurred at intervals of 2000 to 3000 years, much more frequently than the 7000-to 10,000-year pacing of massive ice discharges associated with Heinrich events. The calving cycles correlate with warm-cold oscillations, called Dansgaard-Oeschger events, in Greenland ice cores. Each cycle records synchronous discharges of ice from different sources, and the cycles are decoupled from sea-surface temperatures. These findings point to a mechanism operating within the atmosphere that caused rapid oscillations in air temperatures above Greenland and in calving from more than one ice sheet. 相似文献
19.
An optical analog correlation technique was used to detect morphologic abnormalities in rat liver cells. The method employs an optical matched filter for correlating a test pathological specimen with a control specimen. Experimental results show appreciable promise that such an optical correlator can be employed as a tool for rapid mass screening of a variety of pathological specimens. 相似文献
20.