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101.
Auer PL 《Science (New York, N.Y.)》1974,184(4134):295-301
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Abstract CASE HISTORY: In 2008, a 3-year-old female Labrador Retriever was presented for routine breeding soundness evaluation. CLINICAL FINDINGS: Vaginal endoscopy revealed an 8-cm long and 1-cm thick vaginal septum. Surgical resection of the septum was performed under general anaesthesia using a bipolar high-frequency resectoscope. Three months later the bitch was naturally mated and subsequently delivered five male and two female puppies without complications. Both female puppies were examined at the age of 12 and 15 months and showed a vaginal septum with a diameter of 0.3 and 0.5 cm, respectively. DIAGNOSIS: Vaginal septa in three related bitches. CLINICAL RELEVANCE: This is the first report describing the use of a bipolar high-frequency resectoscope for vaginal surgery in dogs. The septum could be resected quickly, with preservation of surrounding structures. Furthermore, it is the first report collecting information about familial presentation of vaginal septa in female dogs. Based on this case, we suggest that consideration should be given to the possible risk of inheritance of vaginal septa before considering surgical resection and breeding of female dogs. 相似文献
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OBJECTIVE: To evaluate postoperative complications and long-term outcome of simple mandibular fractures involving the molar teeth in cattle. ANIMAL POPULATION: Seventeen cattle with mandibular fractures involving the molar teeth with disruption of the occlusal surface. METHODS: Treatment consisted of application of AO/ASIF-Pinless External Fixators (Synthes, Paoli, PA) in 14 cows, interdental wire stabilization in 1 cow, and conservative treatment in 2 cows. Long-term outcome was determined by telephone contact with the owners, and whenever possible, cows were reevaluated by physical, intraoral, and radiographic examination of the fracture site. RESULTS: Loosening of the fixation device (4 cattle) and bone sequestration (11 cattle) were the most commonly encountered complications. Oral incontinence during rumination was a minor complication in 1 cow. The mean (+/- SD) time the cattle were in production was 26 (+/- 14) months, with 10 cows still alive at follow-up examination; 9 cows were reevaluated. On intraoral examination there was a step in the occlusal surface at the level of the healed fracture site in 3 cows, wave and shear mouth formation in 3 cows, and enamel point formation in 1 cow. Radiographically, all the reevaluated fractures had healed, and there were no signs of tooth root infection. CONCLUSIONS: Complications during healing were bone sequestration and loosening of the fixator. None of the cows was removed from production because of fracture-associated complications, but decreased milk yield occurred in 2 cows. Tooth abnormalities developed in 6 cows, but function of the mandible was not altered. CLINICAL RELEVANCE: Mandible fractures involving the molar teeth carry a good prognosis for return to normal function. Radiographic follow-up is necessary to detect bone sequestration. 相似文献
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OBJECTIVE: The purpose of this study was to evaluate globe position, muscle relaxation and changes in ventilatory parameters after intravenous administration of 0.1 mg/kg rocuronium. STUDY DESIGN: Prospective clinical study. ANIMAL STUDIED: Sixteen dogs of different breeds, with a body weight of 22.1 +/- 13 kg and age of 5.6 +/- 2.8 years (mean +/- SD), were anesthetized for a short ophthalmic examination requiring central position of the globe. PROCEDURES: All dogs were premedicated with 0.005 mg/kg medetomidine and 0.1 mg/kg methadone IV. Anesthesia was induced with propofol to effect and maintained with 10 mg/kg/h propofol by continuous rate infusion. Following endotracheal intubation all dogs breathed 100% oxygen via an anesthetic circle system. Neuromuscular function was assessed with an acceleromyograph (TOF-Guard, Organon Teknika NV, Turnhout, Belgium) and by stimulation of the nervus peroneus superficialis. The ventilation parameters were measured using spirometry and capnography. After baseline measurements 0.1 mg/kg rocuronium was administered IV. Minute volume (MV), tidal volume (Vt), respiratory rate (RR), end expiratory carbon dioxide concentration (PE'CO(2)) and maximal depression of the response of the first twitch (T1) of train-of-four (TOF) stimulation and train-of-four ratio (TOFR) was measured. The change in the position of the globe was recorded. RESULTS: T1 decreased to 61 +/- 18% and the TOF ratio to 45 +/- 21% of baseline values. Both parameters returned to baseline after 9 min. There was no significant reduction in MV, TV and RR and no increase in PE'CO(2). The globe rotated to a central position of 45 +/- 7.7 s after administration of rocuronium and remained there for 23 +/- 10.8 min in all dogs. CONCLUSION: Rocuronium administered intravenously at a dose of 0.1 mg/kg to dogs causes a central position of the globe but minimal impairment of ventilation parameters. 相似文献
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ObjectiveTo review the evidence regarding the reversal of neuromuscular block (NMB) in companion animals with emphasis on the development and use of newer agents.Database usedData sources include scientific reviews and original research publications in both human and veterinary literature using Pubmed and Scopus as search data bases. Unpublished and locally published data on reversal of NMB are presented.ConclusionsResidual NMB has been shown to increase morbidity and mortality in humans and needs to be avoided. It can be detected only by adequate neuromuscular monitoring. The proper use of reversal agents avoids residual NMB and recurarization should not occur. Anticholinesterase inhibitors, such as edrophonium and neostigmine have been used to reverse NMB when the need for this has been established. Reversal is influenced by several factors and a number of undesirable side- effects of these drugs have been reported. Sugammadex, a γ-cyclodextrin, which was designed specifically to encapsulate rocuronium, is more rapid in its actions, has fewer side effects and can reverse profound NMB induced by aminosteroidal muscle relaxants. 相似文献
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