Prevention of renal carriage of leptospirosis in dogs by vaccination

Dogs vaccinated with a Leptospira interrogans vaccine containing serogroups Canicola and Icterohaemorrhagiae and prepared from cultures grown in a protein-free medium resisted challenge with heterologous representatives of these serogroups. In contrast, control dogs were pyrexic and leptospires were isolated from the blood for nine days following Canicola challenge and six days after Icterohaemorrhagiae challenge. Leptospires were isolated from the urine of controls throughout the post challenge period and from kidneys at post mortem examination of six out of six and four out of six Canicola and Icterohaemorrhagiae challenged controls, respectively. There have been no reports of hypersensitivity reactions to this vaccine since its introduction in 1980.     

槟榔红色素的抗氧化活性

测定槟榔红色素(areca red pigment,AP)对 DPPH·和·OH的清除能力、对脂质体过氧化的抑制能力、对Fe2+的络合能力,并测定其还原能力.结果表明:槟榔色素对DPPH·、·OH的清除能力较强:对脂质体过氧化的抑制能力很强,抑制率高达79.84%;与VE、没食子酸(gallic acid,GA)、BHT相比,槟榔色素的还原力、对Fe2+的络合能力较弱.说明槟榔红色素是较好的抗氧化剂.     

A NEW ESTROGENIC SUBSTANCE PRESENT IN THE NEUTRAL FRACTION OF HUMAN PREGNANCY URINE

In addition to the well-defined phenolic estrogens in human pregnancy urine there appears to be another estrogenic substance which is a neutral non-ketonic compound.