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81.
Evi Pecceu Brittainy Stebbing Yolanda Martinez Pereira Ian Handel Geoff Culshaw Hannah Hodgkiss-Geere Jessica Lawrence 《Veterinary research communications》2017,41(4):249-256
Vasovagal tonus index (VVTI) is an indirect measure of heart rate variability and may serve as a marker of disease severity. Higher heart rate variability has predicted lower tumour burden and improved survival in humans with various tumour types. The purpose of this pilot study was to evaluate VVTI as a biomarker of remission status in canine lymphoma. The primary hypothesis was that VVTI would be increased in dogs in remission compared to dogs out of remission. Twenty-seven dogs were prospectively enrolled if they had a diagnosis of intermediate to high-grade lymphoma and underwent multidrug chemotherapy. Serial electrocardiogram data were collected under standard conditions and relationships between VVTI, remission status and other clinical variables were evaluated. VVTI from dogs in remission (partial or complete) did not differ from dogs with fulminant lymphoma (naive or at time of relapse). Dogs in partial remission had higher VVTI than dogs in complete remission (p = 0.021). Higher baseline VVTI was associated with higher subsequent scores (p < 0.001). VVTI also correlated with anxiety level (p = 0.03). Based on this pilot study, VVTI did not hold any obvious promise as a useful clinical biomarker of remission status. Further investigation may better elucidate the clinical and prognostic utility of VVTI in dogs with lymphoma. 相似文献
82.
Twelve male buffalo calves of 10 to 12 months of age were divided into 3 groups of four each. They were fed wheat straw+concentrate
mixture +3 Kg greens. The chemical composition of the diet was same in all the three groups except fluoride which was added
(as NaF) in concentrate mixture of group B and C to make the final fluoride concentration 30 ppm and 60 ppm respectively.
The animals were kept on scheduled diet for a period of 90 days. Body weights were recorded at the start of the experiment
and at fortnightly interval thereafter. Analysis of data revealed that the dry matter intake decreased non significantly in
group B and C as compared to control group. A significant decrease in serum calcium and a significant increase in phosphorus
concentration were observed in group C animals. A significant increase was observed in alkaline phosphatase activity in group
C animals. A non significant decrease was observed in T4 values in group C animals. On the basis of these results it could be concluded that fluoride in the diet of buffalo calves
@ 30 ppm is a safe level whereas 60 ppm has affected the blood metabolites. 相似文献
83.
Abiodun A. Adesiyun Geoff T. Fosgate Anil Persad Mervyn Campbell Ravi Seebaransingh Alva Stewart-Johnson 《Tropical animal health and production》2010,42(8):1685-1694
The preliminary study was conducted to assess the virulence of a strain of Brucella abortus (1969D) and to compare the susceptibility of water buffalo and cattle calves to infection by the intraconjunctival route.
Seven of each cattle and water buffalo (Bubalus bubalis) calves aged 3–6 months were inoculated intraconjunctivally with counts ranging from 1.5 × 107 to 1.7 × 1010 colony forming units of B. abortus. Animals were monitored over an 8-week period for clinical manifestations and serological and hematological evidence of infection.
At slaughter, eight lymph nodes from each animal were sampled for bacteriological and histopathological assessments. Lymph
nodes from three water buffalo (43%) and five cattle (71%) yielded B. abortus (P = 0.048). Parotid/prescapular lymph nodes were most sensitive in detecting B. abortus. Our data suggest that B. abortus strain 1969D may be used as challenge strain, and water buffalo appeared to have a lower susceptibility to B. abortus infection than cattle. 相似文献
84.
Yaser Hosny Elewa Mohammad Hafez Bareedy Ahmed Awad Abu Al Atta Osamu Ichii Saori Otsuka Tomonori Kanazawa Shin-Hyo Lee Yoshiharu Hashimoto Yasuhiro Kon 《Veterinary research communications》2010,34(6):557-567
Previously, the distribution of myoepithelial cells (mecs) in the salivary glands was studied by both immunohistochemistry,
and transmission electron microscopy; however, little was elucidated concerning their morphological features, especially in
goats. This study was performed to investigate the correlation between the cytoarchitecture of the mecs in goat major salivary
glands (parotid, mandibular, and sublingual glands) and the nature of the saliva secretion. The cytoarchitectural features
of the mecs were examined by scanning and transmission electron microscopy as well as immunohistochemically. The secretory
endpieces in the parotid gland are of the pure serous type, but in both the mandibular and sublingual glands they are of the
mixed type. In all studied glands, the intercalated ducts were covered by mecs which, unlike the large stellate cells that
surrounded the secretory endpieces, were spindle-shaped with few cytoplasmic processes. Interestingly, the mecs were found
to bulge on the basal surfaces of the serous acini and intercalated ducts in all glands and to be in close contact to the
seromucous tubules surface in the mandibular and sublingual glands forming a continuous network around it. In conclusion,
the differences in the degree of development of the mecs as well as the number of their cytoplasmic processes may be correlated
with the nature of the secretion and the number of the secretory granules. Thus these observations may have some relevance
in the diagnosis of atrophy and pathogenic conditions of these glands. 相似文献
85.
Epizootic hemorrhagic disease virus (EHDV) is a vector-borne disease of ruminants disseminated in the tropic and subtropic
zone of the world. Gazella subgutturosa subgutturosa (goitered gazelle) is native species of Anatolia. Due to risk of extinction, captured gazelles have been taken under protection
in a restricted area at Ceylanpinar state farm. In this study, the presence of EHDV was investigated serologically in 82 goitered
gazelle and 399 cattle. Seropositivity rates in goitered gazelle and cattle were detected as 2.43% and 3.50%, respectively. 相似文献
86.
Krishna Mohan Vijay Kumar Mihir Sarkar B. S. Prakash 《Tropical animal health and production》2010,42(1):21-26
The objective of this study were (1) to establish the duration of behavioral estrus signs and timing of ovulation in Murrah
buffaloes (n = 10) and (2) to determine relationship between behavioral estrus signs with change in plasma estrogen concentrations.
Estrus and its behavioral signs were detected at hourly intervals by visual observations, per recta examination of genitalia
and bull parading four times in a day for 30 minutes each. Among the behavioral signs of estrus, swollen vulva (80%) was the
best indicator of estrus followed by excitement (70%). Among the duration of behavioral estrus signs the first and longest
duration of estrus signs was swollen vulva which was seen upto 19.8 ± 0.8 h after onset of estrus. The mean total duration
of estrus symptoms from appearance to disappearance of all the behavioral estrus symptoms was 23.5 ± 1.7 h. All the behavioral
estrus symptoms were observed during the period of estrogen surge. Endocrine profile during the periestrus period showed that
the mean peak concentrations of total estrogen 23.9 ± 3.9 pg/ml occurred at 8.8 ± 1.7 h after onset of estrus. The average
number of estrus symptoms observed per animal during onset of spontaneous estrus was 5.7. Ovulation occurred after 37.4 ± 1.7 h
after onset of estrus and 13.4 ± 1.0 h after end of total estrogen surge respectively. In conclusion, our results suggest
that all signs of behavioral estrus occurred during the preovulatory rise in estrogens. The first sign of estrus to be observed
was a swollen vulva and this symptom persisted the longest. 相似文献
87.
88.
After very hot summer, 22 sheep from 5 different flocks consisting of approximately 150-200 animals each were diagnosed with facial eczema in September 2005, in southwest Turkey. Photophobia, corneal opacity, severe ulcers of the facial skin, especially localized around the eyes and mouth, and 3% mortality were the most prominent clinical symptoms. GGT levels of the animals were very high and varying between 261- 328 U/l. While the activities of ALT and total bilirubin were elevated and AST was normal in affected sheep. Total bilirubin level was higher than normal. Seven of the 22 sheep were euthanatized and necropsy was performed on all of these animals. Severe icterus, hepatomegaly, enlarged gallbladder, congestion of mesenteric vessels were the common necropsy findings. Histopathological changes of the liver included necrosis of the hepatocytes, cholangiohepatitis characterized by mononuclear inflammatory cell infiltrate in the portal area and mild to severe fibrosis around bile ducts. A diagnosis of sporidesmin toxicosis was made based on the histopathology of the livers, the elevation in liver enzymes, and the development of cutaneous lesions consistent with photosensitization and high spore counts in the ruminal contents. Surviving sheep were treated with procaine penicillin + dihidrostreptomycin sulfate, multivitamin complexes and flunixin meglumine. Additionally, zinc sulphate was also given at a dose of 6 gr per 100 lt drinking water for 28 days. All treated sheep recovered. Pasture spore counts were between 96,300- 267,500 spores/g grass. 相似文献
89.
Shahbazfar AA Mardjanmehr SH Arab HA Rassouli A Abdollahi M 《Tropical animal health and production》2011,43(4):843-849
Artemisinin has been used for centuries to treat malaria, intestinal tract helminthosis, diarrhea, and used as an antipyretic
and sedative agent, but the usage in veterinary medicine is a new field. Recently, it has been used successfully to control
experimental poultry coccidiosis. The present study aimed to determine the effects of different doses of artemisinin in broiler
chickens with chronic usage. Sixty birds divided into one control and four treatment groups that fed rations mixed with artemisinin
at doses of 17, 34, 68, and 136 ppm for 36 days. During the experiment, birds showed no clinical signs except anemia. In microscopic
examinations, heart, lung, and spleen had no lesion, but liver, kidney, and brain showed various lesions. Degenerative lesions
like intracytoplasmic eosinophilic inclusions were seen in both kidney and liver but fatty change was seen only in liver.
There was no relationship between severity of the liver lesions and drug dosage. Central chromatolysis, scattered neuronal
necrosis, and mild spongy changes were observed in five regions of the brain that were chosen for sectioning (motor cortex,
cerebellar nuclei, midbrain nuclei, and hindbrain nuclei at two separate levels). Severity of lesions in brain was dose-dependent,
and cerebral cortex was the most vulnerable area. Haematologic tests showed lower values for hematocrit and red blood cell
count dose-dependently. In conclusion, artemisinin is a promising drug for prevention and control of coccidiosis in broiler
chickens and its side effects are not too much serious especially at therapeutic doses. 相似文献
90.
Megersa B Biffa D Abunna F Regassa A Godfroid J Skjerve E 《Tropical animal health and production》2011,43(3):651-656
The involvement of Brucella infection in causing abortion was investigated in a breeding female subpopulation of 283 cattle, 756 camels, and 757 goats.
Serum samples were serially tested using the Rose Bengal test and complement fixation test. The study showed that anti-Brucella antibodies were prevalent in 10.6% (95% confidence interval (CI), 7.4, 14.9), 2.2% (95%CI, 1.4, 3.7), and 1.9% (95%CI, 1.1,
3.2) of cattle, camel, and goats, respectively. Abortion was more commonly reported in camels (23.4%) than cattle (13.8%)
and goats (12.4%). The results of this study suggested that Brucella infections contribute significantly to abortion in cattle (odds ratio (OR), = 4.7; 95%CI, 2.0, 10.8) and goats (OR = 6.9;
95%CI, 2.2, 21.7) but not in camels. The number of young animals produced by breeding females seems to be apparently reduced
in seropositive groups. Keeping more than two animal species at household level was found to be the risk factor for cattle
(OR = 3.1; 95%CI, 1.2, 7.9) and camel (OR = 5.3; 95%CI, 1.2–23.5) seropositivity to Brucella infection when compared to those animals from households that keep only two animal species. This may suggest a possibility
of cross species transmission of Brucella infection under such mixed herding. Wet season (OR = 4.8; 95%CI, 1.3, 18.1) was found to be associated with seropositivity
in goats, linked to a coincidence of increased deliveries in flocks with possible excretion of Brucella organisms. The study results suggest that Brucella infection is the likely cause of abortion in cattle and goats while other causes largely outweigh brucellosis as a cause
of abortion in camels in Borana, hence, contributing to reproductive loss. 相似文献