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11.
Sayaka MATSUMOTO Tomomi TANAKA Natsumi ENDO 《The Journal of reproduction and development》2021,67(2):83
Estrus synchronization requires multiple treatments of hormonal drugs, requiring considerable time and cost. The aim of the present study was to develop an estrus synchronization protocol using intravaginal administration of estradiol benzoate (EB) capsules in goats. Two types of capsules were prepared: an EB capsule that melted immediately after administration and a sustained-release (SR) EB capsule that dissolved slowly and reached a peak after 24 h. Goats with functional corpus lutea were intramuscularly treated with prostaglandin F2α (PG). At 24 h after PG administration, goats were administered 1 mg of EB solution intramuscularly (PG + 24IM; n = 6) or 1 mg of EB capsule intravaginally (PG + 24EB; n = 6). The SR EB capsule was administered intravaginally at the time of PG administration (PG + SR; n = 6). The control group (n = 6) received only PG. All groups showed estrus within 72 h after PG administration. The onset of estrus did not differ significantly between the PG + 24IM and PG + SR groups but was earlier than in the control group. Estradiol concentration in the PG + SR group peaked at 11.5 ± 6.1 h after EB and PG administration. Peak estradiol concentrations were not significantly different between the PG + 24IM and PG + SR groups (78.0 ± 25.8 and 64.0 ± 38.1 pg/ml, respectively), and were higher than the PG + 24EB and control groups (27.3 ± 8.8 and 14.6 ± 6.1 pg/ml, respectively). These results suggest that intravaginal administration of an EB capsule with a sustained-drug release base is applicable for estrus synchronization, as an alternative to intramuscular administration. 相似文献
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The spectral data of a new triterpene, cucurbita-5,23-diene-3beta,25-diol, isolated from the seeds of Sicana odorifera, are reported. 相似文献
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New method to evaluate water-soluble antioxidant activity based on protein structural change 总被引:1,自引:0,他引:1
Terashima M Nakatani I Harima A Nakamura S Shiiba M 《Journal of agricultural and food chemistry》2007,55(1):165-169
A simple method to evaluate antioxidant activities of water-soluble ingredients of foods has been developed. Protective effects of antioxidants against hypochlorite radical or hydroxyl radical have been studied by comparing changes in absorbance of myoglobin (a standard reference) at 409 nm. Protective ratio, defined by absorbance changes of myoglobin with or without the antioxidant, was a good indicator to quantitatively evaluate the antioxidant activity against the hypochlorite radical or the hydroxyl radical, respectively. Radar charts indicating the antioxidant activities against DPPH (1,1-diphenyl-2-picrylhydrazyl), hypochlorite radical, and hydroxyl radical clearly differentiated the characteristics of five antioxidants including carnosine, glutathione, and vitamin C. By comparison of the radar charts, antioxidant activity of bonito meat hydrolysate was found to have similar characteristics to that of carnosine. The simple method proposed in this study would be useful for evaluating and characterizing the activities of water-soluble antioxidants contained in various food materials. 相似文献
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Muramatsu Y Hukuta K Satoh S Muramatsu M Nishimura M Nagahata H Ueno H Morita C Tamura Y 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2006,68(9):1007-1008
The indirect fluorescent antibody test (IFAT) revealed seropositivity to Coxiella burnetii in aged non-laying chickens in poultry farms in a prefecture in the central part of Japan. Seropositivity was 7%, and antibody titers ranged from 16 to 64. No DNA fragment specific for C. burnetii was detected in the chickens by nested-PCR. The prevalence of C. burnetii infection in a prefecture of Japan in which poultry farming prospers was 7%. 相似文献
15.
S Kemmochi H Hayashi E Taniai K Hasumi Y Sugita-Konishi S Kumagai K Mitsumori M Shibutani 《Journal of toxicologic pathology》2012,25(2):149-154
Activators of tissue proteolysis including Stachybotrys microspora triprenyl phenol (SMTP)-7 are a new class of agents that are expected to be effective for amelioration of chronic tissue destructive diseases. The present study was performed to examine whether SMTP-7 is effective for the amelioration or protection of early-stage IgA nephropathy (IgAN) induced by nivalenol (NIV) in female BALB/c mice. In Experiment 1, mice were administered NIV at 24 ppm in diet for 8 weeks, and during the NIV treatment, they were intraperitoneally injected with SMTP-7 (10 mg/kg) three times a week. In Experiment 2, mice were injected similarly with SMTP-7 during the last 4 weeks of a 16-week NIV treatment. Immunofluorescence analysis revealed an inhibitory effect of SMTP-7 on the glomerular deposition of IgA in Experiment 1; however, it was ineffective in Experiment 2. On the other hand, SMTP-7 did not affect the serum concentration of IgA in both experiments. These results suggest that SMTP-7 has a potential to decrease the progression of IgAN induced by NIV through inhibition of local accumulation of IgA in the glomerular mesangium, while it was ineffective for suppression of IgA production. On the other hand, SMTP-7 was found to be ineffective for already deposited IgA, suggesting that SMTP-7 may not be effective for ameliorating advanced IgAN. 相似文献
16.
Koji Tanaka Sayaka Nakatsu Zen-nosuke Katsuba Hiroshi Furuya Takao Tsuchiya Takashi Oku 《Journal of General Plant Pathology》2005,71(2):144-146
The pathogenic races of 450 cultures of Xanthomonas oryzae pv. oryzae, isolated from eight locations in the inland mountainous area of Hiroshima Prefecture during 2000 to 2003, were determined with a set of Japanese differentials. The rice cultivars infected with the bacterium are thought to be in the Kinmaze group, which does not have any resistance genes. Five Japanese races IA, IB, II, V, and VII occurred across the area, although the composition of the races in each location altered during the surveyed 4 years. 相似文献
17.
Arata S Hashizume C Kikusui T Takeuchi Y Mori Y 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2008,70(10):1107-1110
Glutamate decarboxylase (GAD) is the primary enzyme in the brain that catalyzes the synthesis of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter. There are two isoforms named according to their molecular weights, GAD67 and GAD65, which are encoded by GAD1 and GAD2, respectively. To investigate the association between GAD genes and temperament in domestic dogs, Canis familiaris, we sequenced the full lengths of the coding regions of these genes and identified three single nucleotide polymorphisms (SNPs) in GAD1 and one in GAD2. When comparing genotype and allele frequencies of SNPs among five breeds with different behavioral traits, statistically significant interbreed differences were observed for three SNPs in GAD1. These results suggest that GAD1 SNPs may be useful for behavioral genetic studies in dogs. 相似文献
18.
Kyoko Kinoshita Sayaka Tamaki Miho Yoshioka Sarawut Srithonguthai Tadao Kunihiro Daigo hama Kouichi Ohwada Hiroaki Tsutsumi 《Fisheries Science》2008,74(1):77-87
ABSTRACT: For bioremediation of organically enriched sediment deposited below fish farms, the extremely high potential for population growth of a deposit-feeding polychaete, Capitella sp. I, in the organically enriched sediment, and the effect on decomposition of organic matter in the sediment, were examined. A mass-culturing technique was conducted for this species. Bioremediation experiments were conducted on the organically enriched sediment in a fish farm in Kusuura Bay, Japan in 2003–2006. Approximately 1.7 million individuals of the worms were placed on the sediment below one net pen in December 2003, 9.3 million individuals in November 2004, and 2.2 million individuals in November 2005. After the worms were spread on the sediment, they rapidly increased in number and reached the highest densities of approximately 134 000 inds/m2 in February 2004, 527 000 inds/m2 in March 2005 and 103 000 inds/m2 in January 2006. In the process of rapid population growth, the decomposition of the organic matter of the sediment was enhanced markedly. Our results demonstrate that the promotion of population growth by spreading cultured colonies of Capitella can enhance the decomposition rate of organic matter markedly in organically enriched sediment below fish farms. This method is promising for minimization of the negative effects of fish farms. 相似文献
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Ayumi Kobayashi Sayaka Takahashi Masaaki Ono Kiyoshi Tanaka Masato Kishima Masato Akiba Ikuo Uchida 《Acta veterinaria Scandinavica》2014,56(1):31