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Rúbia Monteiro de Castro Cunha Gleidice Eunice Lavalle Fernanda Camargo Nunes Ayisa Rodrigues de Oliveira Renato de Lima Santos Roberto Baracat de Araújo 《Veterinary and comparative oncology》2023,21(2):240-254
Squamous cell carcinoma (SCC) is an important malignancy in dogs, due to its incidence and clinical presentation, which can be of locally aggressive single or multiple lesions with a metastatic potential. The objective of this investigation was to evaluate SCC response to treatment, anatomopathological and immunohistochemical characteristics, disease-free interval and overall survival time. 54 dogs with histopathologically diagnosed SCC were included in this study. Their mean age was 9.16 years with a range of 1–14 years. Of the 54 animals in the study, 34 (65.4%) had white skin and white fur coats. There was a significant correlation between fur coat colour and the development of tumours in areas of sun exposure (p = .001). Animals with tumours in areas of the body exposed to the sun had longer overall survival time than animals with tumours in areas not associated with sun exposure (p = .001). Surgery combined with electrochemotherapy (ECT) yielded a survival rate 32% higher than using a surgical approach alone (HR = 0.32, p = .038, IC = 0.11–0.94). ECT, with or without surgery, had an objective response rate of 90.9%. Local lymph node and/or distant site metastasis at diagnosis, or at some point during follow-up, occurred in 34.6% (18/52) of animals. Animals with tumours in sun exposed locations had more aggressive histopathological characteristics but had longer overall survival time. This is probably due to individualised therapeutic treatment with both surgery and ECT. 相似文献
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Robson RV Alves Tatiana Soares Elinaldo FL Bento Ricardo S Roldan‐Filho Brbara SS Souza Marcele KN Lima Jssica S Nascimento Luana CBB Coelho Roberto A S Thmarah A Lima Gabriel GA Gonalves Fbio A Brayner Luiz C Alves Daniela MAF Navarro Thiago H Napoleo Patrícia MG Paiva 《Pest management science》2020,76(2):730-736
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Sidney F. Bandeira Roberto S.G. Silva Jaqueline M. Moura 《Journal Of Aquatic Food Product Technology》2017,26(4):447-456
The Whitemouth croaker (Micropogonias furnieri), due to its abundance, is considered one of the most traditional and important species fished in the coastal waters and estuaries of South America. The aim of this work was to produce biopolymeric films of gelatins obtained from skin and bones of Whitemouth croaker. The fish gelatins were characterized through the yield, chemical composition, physiochemical, and rheological properties. The films were characterized by tensile strength (TS), elongation at break (EAB), water vapor permeability (WVP), thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FT-IR), and optical properties. The values of protein yield, hydroxyproline content, gel strength, melting temperature, gelling temperature, and viscosity of the skin gelatin were higher than the values of the bone gelatin. The films obtained of skin gelatin showed all properties and thermal analysis superior in relation to the films of bone gelatin; this can be justified by the best physicochemical and rheological characteristics of the skin gelatin. 相似文献
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The effects of starving and feeding on Dover sole (Solea solea,Soleidae, Linnaeus, 1758) stress response and early larval development
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Chiara Carla Piccinetti Marco Donati Giuseppe Radaelli Giovanni Caporale Gilberto Mosconi Francesco Palermo Lina Cossignani Roberto Salvatori Rocio Penuela Lopez Ike Olivotto 《Aquaculture Research》2015,46(10):2512-2526
In the view of an urgent necessity to improve the quantity and the quality of farmed fish species, there is a strong need to improve our basic knowledge on the effects of first feeding during the developmental stages of fish larvae. High mortality, mainly due to food deprivation or inappropriate food quality, has been observed in many larval fish species, but knowledge about the morphological, biochemical and molecular processes related to this topic is still poorly understood. The understanding of the early larval ontogeny as well as the larval nutritional requirements and the molecular and cellular mechanisms elicited by fish larvae during food deprivation and starvation are thus of primary importance. At this regard, this study investigates, in Dover sole larvae, the effects of starvation and starving/re‐feeding procedures at a morphological, histological, biochemical and molecular level. The results evidenced that starved larvae progressively decrease in growth, lipid content, affected their gastrointestinal tract and muscle development and increased cortisol and heat shock protein 70 levels. On the contrary, starved and re‐fed larvae showed, after the restoration of a favourable feeding condition, a compensatory growth. In conclusion, this is the first study analysing through a multidisciplinary approach the effects of food deprivation on the development of an important economic species, the Dover sole. 相似文献
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Roberto Venegas Thomas Oliver Russell E. Brainard Mudjekeewis Santos Rollan Geronimo Matthew Widlansky 《Fisheries Oceanography》2019,28(2):117-130
We investigated projected changes in sea surface temperature (SST) and the associated impacts on spawning habitat for skipjack tuna (Katsuwonus pelamis) in the Coral Triangle region (CT). A multimodel aggregate of SST CMIP5 models for the CT region, based on a comprehensive skill validation assessment, was used to identify the five best performing of 36 models tested for inclusion in a regional multimodel ensemble. Monthly 1° SST multimodel aggregate projections for the CT region under RCP8.5 show that increases in SST, as high as 2.8°C (mean value), will likely occur by the end of this century. Using these estimates of SST change, we applied three parameterizations of skipjack tuna spawning temperatures to assess the potential for change in spawning habitat within the CT region. The three spawning temperature parameterizations were as follows: (a) a square‐wave function derived from catch data with boundaries at 26 and 30°C; (b) a symmetric Gaussian function derived from the SEAPODYM models; and (c) an asymmetric Gaussian function that modifies the SEAPODYM curve in (b) to include the results of relevant physiological experiments. All three parameterizations show similar geographic patterns, with the amount of favourable spawning habitat decreasing throughout the central, equatorial CT region and increasing at higher latitudes. However, the three parameterizations show marked differences in the modelled magnitude of change, with an asymmetric Gaussian function (ASGF) showing a regionwide average of 66.1% decline in favourable spawning habitat between 2015 and 2099. These projected changes in tuna spawning habitats are likely to have important consequences on local and regional fisheries management in the CT region. 相似文献
18.
Milene Miranda Praa Carlos Roberto Carvalho Wellington Ronildo Clarindo 《Scientia Horticulturae》2009,122(3):501-505
A relatively rapid, practical and reliable procedure for in vitro production of tetraploid tomato using colchicine is described. Using this procedure 11.11% generation of tetraploids was obtained after exposure of seedling shoot meristem explants with 8 mM colchicine for 96 h. Confirmation of tetraploid production (2n = 48), was determined by flow cytometry and verified by cytogenetic analysis of root tip preparations. The results indicate that the procedure is adequate for induction and screening of tetraploid tomato plantlets. 相似文献
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The effects of (S)-(+)-carvone treatments on seed potato tuber dormancy and sprouting 总被引:1,自引:0,他引:1
Summary Potato seed tubers may suffer from premature sprouting during storage, thus limiting their suitability for cultivation. Commonly
used sprout suppressant treatments negatively affect but viability and therefore a reliable method to inhibit bud development
must still be found for seed tubers. The monoterpene carvone ((S)-(+)-carvone) was tested in small scale experiments. The
vapour of this compound fully inhibited bud growth of tubers cv. Monalisa stored at 23°C without affecting bud viability throughout
6 months of treatment. The most effective range of carvone vapour concentrations was between 0.34 and 1.06 μmol mol−1. With these qualities we can expect carvone to become a suitable sprout suppressant for seed tubers. 相似文献