The duration of immunity to an inactivated adjuvanted canine parvovirus vaccine. A 52 and 64 week postvaccination challenge study

Dogs were successfully isolated for a period of either 52 or 64 weeks following vaccination with an inactivated, adjuvanted canine parvovirus-2 vaccine. Antibody persisted in all ten vaccinated dogs, although in one case by 52 weeks postvaccination only virus neutralizing antibody, and not hemagglutination-inhibiting antibody, could be detected. Sentinel unvaccinated dogs housed alongside the vaccinated dogs throughout the study remained free of canine parvovirus-2 antibody until challenged. Upon oral challenge with canine parvovirus-2 infected material all unvaccinated dogs developed one or more signs of canine parvovirus-2 disease, shed virus and developed antibody. None of the vaccinated dogs became overtly sick. Of the five vaccinated dogs challenged 52 weeks after vaccination, three shed virus and one showed a significant rise in antibody. At 64 weeks after vaccination only one of the five challenged dogs shed virus and showed a boost in antibody titer.     

The Management of Prostaglandin-controlled Breeding Programs in Beef Cattle - A Five Year Study

A herd of 180 beef cows was synchronized with prostaglandin and bred by artifical insemination for five successive years. Factors influencing the success or failure of estrus synchronizing programs were identified, including the management of nutrition, postpartum interval, cow age and artificial insemination technology. Specific recommendations on the management of prostaglandin-controlled breeding programs resulted in improving the pregnancy rates from 33% in year 1 to 67% in year 5. Improved management and close veterinary supervision were shown to improve the success of an estrus synchronization program.     

The F38-Like Group,a New Group of Caprine Mycoplasmas?

This paper concerns the taxonomic status of the F38-like group (MacOwan), a prime determinant of contagious caprine pleuropneumonia (CCPP). Extensive biochemical and serological investigations on strain F38 are reported. Some complex serological relationships with other mycoplasma species are revealed. The results, taken in conjunction with earlier published work on geno-typic characters, lead to the conclusion that final classification of these organisms should await further comparative studies of a number of field strains with a related group of strains classified as M. capri-colum.The characterization of F38 confirms its partial relationship to the “M. mycoides group” of ovine/caprine/bovine mycoplasmas, and has also revealed a very close phenotypic relationship to the bovine mycoplasma serogroup 7, a finding of potential diagnostic and epidemiological importance.Key words: mycoplasmas, classification, F38-like group     

Endocrine effects of heat stress in boars

The purpose of this study was to describe the temporal changes in peripheral plasma levels of testosterone and Cortisol in boars during and after heat stress. A total of 8 boars were utilized, 4 of them were exposed to 35°C, for 100 h in a climatic room, and 4 served as controls and were kept at 20 °C for 100 h in the climatic room.Blood samples were obtained via permanent vein catheters 3 times daily from 5 days before heat stress until 20 days after termination of heat stress. Testestorone levels were determined by radioimmunoassay and Cortisol by a competitive protein binding technique.For both hormones the pre-exposure levels were similar in both groups of boars. The control boars had significantly higher testosterone levels, while being in the climatic room, than during any other period. The experimental boars had slightly increased testosterone levels during the first day of heat stress and thereafter continuously decreased levels. In the control boars the testosterone levels returned to pre-exposure levels immediately after removal from the climatic room, whereas in the experimental boars the testosterone levels were dramatically increased during the first 5 days after exposure. The differences in Cortisol levels, between the 2 groups of boars were restricted to the period spent in the climatic room. During this period the experimental boars had significantly higher Cortisol levels.Key words: boars, heat stress, testosterone, cortisol     

Colonic perforation after corticosteroid and surgical treatment of intervertebral disk disease in a dog

Colonic perforation after corticosteroid and surgical treatment of intervertebral disk disease in a dog Perforation of the distal segment of the descending colon, after corticosteroid and neurosurgical treatment for an intervertebral disk herniation, resulted in the death of a 3-year-old, male, Lhasa Apso. Initially, the dog was paraparetic in the hindlimbs, but became paraplegic after 4 days of conservative treatment. Corticosteroids were administered before referral and during decompressive hemilaminectomy. Six days after surgery, the dog had improved neurologically, but was depressed, anorectic, and vomiting. Abdominocentesis revealed septic peritonitis. The dog died shortly after a perforation in the descending colon was surgically corrected.