水稻穿梭育种研究初报

 利用浙江南北跨越27°-31°12′N，相距约450公里的不同生态条件进行穿梭育种研究。从F#-2起在嘉兴、杭州、富阳和温州的不同生态条件下进行选择，所选择的单株相互交换，使每一个试点都种植全部选择的株系，允许选育者根据当地的表现进行淘汰和选择。这样便能在不同的生态条件下对每一世代的当选单株进行适应性鉴定，以选育适应性较广的新品种。通过穿梭育种不仅较易选得适应性较广的品系，而且最后所选得的较优良品系几乎没有一个是选育者从自己推荐的组合中连续选择育成的。这表明穿梭育种还可以通过各育种者扬长避短，共同努力，提高选择效果。现初步育成几个新品系。本文还对今后的穿梭育种工作的改进作了讨论。     

天然落叶松林分生长阶段划分与定向经营

林分生长阶段划分是定向经营不可缺少的基础之一。为此采用Ｆｉｓｈｅｒ最优分割法对黑河地区天然落叶松林的１２２块样地进行了林分生长阶段划分。以研究生长阶段和定向经营的关系。结果表明：黑河地区天然落叶松林分胸径成熟至少需３３￣３４ａ。材积成熟至少需４５ａ以上；阴坡生长期比阳坡长３￣７ａ，生长速率比阳坡慢；阳坡宜于发展短周期商品林；阴坡可用作发展中长周期商品林。     

The crystal structure of a T cell receptor in complex with peptide and MHC class II

The crystal structure of a complex involving the D10 T cell receptor (TCR), 16-residue foreign peptide antigen, and the I-Ak self major histocompatibility complex (MHC) class II molecule is reported at 3.2 angstrom resolution. The D10 TCR is oriented in an orthogonal mode relative to its peptide-MHC (pMHC) ligand, necessitated by the amino-terminal extension of peptide residues projecting from the MHC class II antigen-binding groove as part of a mini beta sheet. Consequently, the disposition of D10 complementarity-determining region loops is altered relative to that of most pMHCI-specific TCRs; the latter TCRs assume a diagonal orientation, although with substantial variability. Peptide recognition, which involves P-1 to P8 residues, is dominated by the Valpha domain, which also binds to the class II MHC beta1 helix. That docking is limited to one segment of MHC-bound peptide offers an explanation for epitope recognition and altered peptide ligand effects, suggests a structural basis for alloreactivity, and illustrates how bacterial superantigens can span the TCR-pMHCII surface.     

和谐社会视角下的大学生家政教育研究

如何教育和培养当代大学生,提高他们生存和发展的综合索质,是亟待研究的时代性课题。对当代大学生进行全面系统的家政教育,使其在未来的家庭生活中具备应有的能力,承担应尽的责任,是促进大学生全面发展的重要环节和帮助大学生实现社会化的有效路径。     

杨树扦插育苗密度和造林密度的理论拟合及其应用

根据杨树光合营养器官的形态解剖特征、应用数学方法，推导出杨树扦插理论模型，再换算求解出造林密度模型。应用实例表明，两模型既有严格的理论基础、又容易取得模型参数，且计算简便，易于生产采纳。     

加强闽台农业合作 促进农民增收

农民增收缓慢已成为制约福建省农业和农村经济发展的核心问题。本文通过分析福建省农民增收的制约因素及台湾农业发展的困境,提出闽台农业合作是实现双赢的重大举措,可以促进两地农业发展,增加农民收入。     

2．5cm桦木地板毛坯快速干燥新工艺

用干球温度不变、湿球温度连续降低的干燥新工艺对2．5cm桦木地板毛坯进行快速窑干，使干燥周期较常规窑缩短了40％，干燥质量好，且易于操作。     

农业院校思想道德修养课典范教学法探索

典范教学法是根据思想道德修养课的教学目标，针对农业院校的专业特点和学生思想实际，在学习借鉴班杜拉社会学习理论的基础上创设的，本文对典范教学法的涵义、具体应用进行了探索与实践。     

CAPP中回转体零件信息的描述与输入方法

根据CAPP系统工艺决策时对零件信息的要求,在对回转体零件构成特性分析的基础上,基于形面描述法的思想,对回转体零件的构成形面进行了分类、定义和编码,确定了各形面的描述参数,构建了零件信息模型,并以此模型为基础完成了零件信息的输入与存贮设计。     

Lenalidomide alone or combined with bortezomib inhibits growth and induces apoptosis in KM3 cells

AIM: To investigate the effects of lenalidomide alone or combined with bortezomib on induction of apoptosis in multiple myeloma(MM) KM3 cells.METHODS: The KM3 cells were treated with lenalidomide alone or combined with bortezomib. The number of viable cells was determined by trypan blue exclusion. Apoptotic cells were simultaneously stained with annexin V-FITC and PI and determined by flow cytometry. RT-PCR was used to examine the level of p65 mRNA. Western blotting was used to examine the protein levels of P65, pP65, caspase-3,-8, -9, and poly (ADP-ribose) polymerase (PARP). RESULTS: Lenalidomide-inhibited the cell growth and induced apoptosis of KM3 cells. The mechanism responsible for lenalidomide-mediated inhibition was via NF-κB and activation of caspase-mediated induction of apoptosis. A synergistic effect was observed when combination of lenalidomide with bortezomib was used. CONCLUSION: Lenalidomide inhibits the growth and induces apoptosis in KM3 cells. There is a synergistical effect when combination of lenalidomide with bortezomib is in use.